<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21760

Description Uncharacterized protein
SequenceMPLRLRNGGHAPHHKAPPFSSSSAHTLSSDNHDRPSGFQPRARVTDRYRIVGFISSGTYGRVYKAVSRPSAGPPPQSVASDGAPFSSEVAIKKFKPDKEGEQISYTGISQSAIREMSLCSELRHANVIRLVEILLEDKCIFMVFEYAEHDLLQIIHHHTQQPRHPIPPATVKSIMFQLLNGCQYLHTNWVLHRDLKPANIMVTSAGEVKIGDLGLARRFDKPLHSLFSGDKVVVTIWYRAPELILGAFHYTPAIDMWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMQKIVDIMGMPTRERWPLLPTMPEFSQLSTLQAPSTHHHFQQQQQHHHHYQQQQQQAQHHAHHLQHHHAHSGSASSSPQRAGAPGSLLEKWYYNTISNAGLGSGSSSAAPSPLSSLGPEGYRLLAGLLEYDPVKRLTAAQALQSSFFSTGDRVSANAFDGLKVEYPHRRVSQDDNDIRTSSLPGTKRSGLPDDSLLRPPKRMKE
Length496
PositionKinase
OrganismOphiocordyceps sp. 'camponoti-leonardi'
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Ophiocordycipitaceae> Ophiocordyceps.
Aromaticity0.08
Grand average of hydropathy-0.500
Instability index52.36
Isoelectric point9.38
Molecular weight55383.17
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP21760
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.97|      19|      31|     363|     385|       1
---------------------------------------------------------------------------
  363-  385 (31.40/25.43)	SGSASSSPqragAPGSLLEKWYY
  395-  413 (35.57/18.98)	SGSSSAAP....SPLSSLGPEGY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.95|      18|      32|      19|      46|       2
---------------------------------------------------------------------------
   19-   36 (32.70/ 9.50)	FSSSSAHTLSSDNHDRPS
   53-   70 (31.25/21.06)	FISSGTYGRVYKAVSRPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.64|      21|      32|     191|     211|       4
---------------------------------------------------------------------------
  191-  211 (35.78/27.88)	LHRDLKPANIMVT...SAGEVKIG
  223-  246 (29.86/22.01)	LHSLFSGDKVVVTiwyRAPELILG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.84|      18|      23|     324|     341|       7
---------------------------------------------------------------------------
  324-  341 (37.48/16.60)	QAPSTHHHFQQQQQHHHH
  345-  362 (36.35/15.93)	QQQQAQHHAHHLQHHHAH
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP21760 with CDK8 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) FDGLKVEYPHRRVSQDDNDIRTSSLPGTKRSGLPDDSLLRPPKRMKE
2) MPLRLRNGGHAPHHKAPPFSSSSAHTLSSDNHDRPSGFQPR
3) TLQAPSTHHHFQQQQQHHHHYQQQQQQAQHHAHHLQHHHAHSGSASSSPQRA
450
1
322
496
41
373

Molecular Recognition Features

MoRF SequenceStartStop
1) EKWYY
2) RIVGFISSGTYGR
3) SLLRPPKRMKE
381
49
486
385
61
496