<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21678

Description Serine/threonine-protein kinase SSN3
SequenceMNYSTTSGGPGGPYRKLNNIPSHQQHHHHAQQNQQQYTQQQLQHQQNLQHIMQQHHHQQQQAQHLQQSQGQLPMRSNMPHHQLPRAASGAGGLVGGVGGGAVGGGGGVGGGPGVGGVGGPGGAVPTSSATFRTNSIPQPALMALNSILTLGPFKHRKDLTRESVLSTYQIMGYIAAGTYGKVYKAKLKNDKPSGSMNNSSSTDDNGNDMLDESIVSPEINLGNGANGNAINNGNAGALPQFYAIKKFKSDNHHHHGNNNGRAGGNNSNNNTVNNLNKSQNQNNQNSIHQDEVLHYTGISQSAIREMSLCRELNNKNITKLVDIILENKSIYMVFEFCEHDLLQIIHYQSHPEFKPIPNSTIKSLIWQILNGVTFLHKNWIFHRDLKPANIMVTSQGVVKIGDLGLARKFKDPLQSLYTGDKVVVTIWYRAPELLLGTRHYTPALDLWAIGCILGEILSLRPMFKGEECKIDLNNKKSVPFQKNQLQKIVEILGTPTTDIWPSLNKYPEYLSFTQNFNQNYINNLSNWFKMINGGNNNNNNSSTSSSTSSTSSTANCLDLLAGLLKYDPEQRLTADQALLHPYFLELPKVTENAFEGLTYKFPNRKIYTDDNDIVTGGGGGNANHHHHHQQVQQQQGQQGQQSQQLQSGGPIQIQQVQQLQQQIQSQQLQGYKRGGMDDLSGGIRKKRG
Length688
PositionKinase
OrganismCandida viswanathii
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Candida.
Aromaticity0.07
Grand average of hydropathy-0.685
Instability index44.51
Isoelectric point9.19
Molecular weight75866.89
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21678
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     140.14|      24|      26|      23|      48|       1
---------------------------------------------------------------------------
   23-   46 (52.98/22.60)	H..QQHHHHAQQNQQ.QYTQQQLQHQQ
   50-   76 (40.51/17.21)	HimQQHHHQQQQAQHlQQSQGQLPMRS
  624-  638 (23.09/ 6.32)	.....HHHHHQQVQQ.QQGQQ......
  639-  655 (23.56/ 6.61)	.........GQQSQQ.LQSGGPIQIQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.12|      14|      16|     508|     523|       3
---------------------------------------------------------------------------
  508-  523 (18.45/13.08)	EYLSFTQNFNQNyiNN
  526-  539 (30.67/15.71)	NWFKMINGGNNN..NN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.25|      13|      29|     350|     363|       6
---------------------------------------------------------------------------
  350-  363 (20.76/17.21)	HPEFKPiPNSTIKS
  382-  394 (23.49/14.27)	HRDLKP.ANIMVTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      28.15|       9|      17|     426|     436|       7
---------------------------------------------------------------------------
  426-  436 (11.93/13.47)	IWyrAPELLLG
  446-  454 (16.22/ 9.02)	LW..AIGCILG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21678 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKLKNDKPSGSMNNSSSTDDNGNDMLDESIVSPE
2) KSDNHHHHGNNNGRAGGNNSNNNTVNNLNKSQNQNNQNSIHQDE
3) MNYSTTSGGPGGPYRKLNNIPSHQQHHHHAQQNQQQYTQQQLQHQQNLQHIMQQHHHQQQQAQHLQQSQGQLPMRSNMPHHQLPRAASGAGGLVGGVGGGAVGGGGGVGGGPGVGGVGGPGGAVPTSSATFRTNSI
4) TDDNDIVTGGGGGNANHHHHHQQVQQQQGQQGQQSQQLQSGGPI
185
248
1
608
218
291
136
651










Molecular Recognition Features






MoRF SequenceStartStop




1) DLSGGIRKKR
2) GPYRKL
3) LQGYKRG
678
12
668
687
17
674