<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21645

Description Serine/threonine-protein kinase SSN3
SequenceMNYSTTSGGPRGPYRKLNNIPSHQQRHHHSQQNQQQYTQQQLQHQQNLQHIMQQHHHHQQQQAQHLQQSQGQLPMRSNMPHHQLPRATSGASGLVGGVGGGVVGGGGGVGGGPGVGGPGGAVPTSSATSRTNSIPQPALMALNSILTLGPFKHRKDLTRESVLSTYQIMGYIAAGTYGKVYKAKLKNDKPNGSMNNNGSSTDDNGNDMLDESIVSPEINLGNGANGNAINNGNAGALPQFYAIKKFKSDNHHHHGNNNGRAGGNNSNNNTVNNLNKNQNQNNQNSIHQDEVLHYTGISQSAIREMSLCRELNNKNITKLVDIILENKSIYMVFEFCEHDLLQIIHYQSHPEFKPIPNSTIKSLIWQILNGVTFLHKNWIFHRDLKPANIMVTSQGVVKIGDLGLARKFKDPLQSLYTGDKVVVTIWYRAPELLLGTRHYTPALDLWAIGCILGEILSLRPMFKGEECKIDLNNKKSVPFQKNQLQKIVEILGTPTTDIWPSLNKYPEYLSFTQNFNQNYINNLSNWFKMINGGNNNNSSTSSSTSTSSTANCLDLLAGLLKYDPEQRLTADQALLHPYFLELPKVTENAFEGLTYKFPNRKIYTDDNDIVTGGGGGNANHHHHQQVQQQQGQQGQQSQQLQSGGPIQIQQVQQLQQQIQSQQLQGYKRGGMDDLSGGIRKKRG
Length683
PositionKinase
OrganismCandida viswanathii
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Candida.
Aromaticity0.07
Grand average of hydropathy-0.714
Instability index43.23
Isoelectric point9.28
Molecular weight75638.69
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats
>MDP21645
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     145.83|      25|      26|      25|      49|       1
---------------------------------------------------------------------------
   25-   48 (44.32/16.16)	....QRHHHSQQNQQQYTQ.....Q...QLQHQQNL
   49-   79 (40.90/14.46)	QhimQQHHHHQQQQAQHLQ.....QsqgQLPMRSNM
  620-  646 (34.47/11.25)	......HHHHQQVQQQQGQqgqqsQ...QLQSGGPI
  647-  664 (26.14/ 7.10)	Q...IQ..QVQQLQQQIQS.....Q...QLQ.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.92|      24|      26|     211|     235|       2
---------------------------------------------------------------------------
  211-  235 (36.87/21.37)	ESIVSPEINLGNGANGNAiNNGNAG
  239-  262 (43.05/21.97)	QFYAIKKFKSDNHHHHGN.NNGRAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.06|      12|      17|      90|     102|       3
---------------------------------------------------------------------------
   90-  102 (19.85/10.68)	GASGlVGGVGGGV
  111-  122 (26.20/10.95)	GGPG.VGGPGGAV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.25|      13|      30|     349|     362|       4
---------------------------------------------------------------------------
  349-  362 (20.76/19.89)	HPEFKPiPNSTIKS
  381-  393 (23.49/16.50)	HRDLKP.ANIMVTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      28.15|       9|      17|     425|     435|       7
---------------------------------------------------------------------------
  425-  435 (11.93/11.76)	IWyrAPELLLG
  445-  453 (16.22/ 7.90)	LW..AIGCILG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.87|      20|     186|     403|     424|       8
---------------------------------------------------------------------------
  403-  424 (31.49/26.73)	GLARKFkdPLQSLYTGDKVVVT
  592-  611 (38.38/25.45)	GLTYKF..PNRKIYTDDNDIVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.41|      24|      30|     471|     499|       9
---------------------------------------------------------------------------
  471-  499 (35.52/33.06)	LNN.KKSVPFQKNQLQKIVEILGTpttdiW
  502-  526 (39.88/24.01)	LNKyPEYLSFTQNFNQNYINNLSN.....W
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21645 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKLKNDKPNGSMNNNGSSTDDNGNDMLDESIVSPE
2) FKSDNHHHHGNNNGRAGGNNSNNNTVNNLNKNQNQNNQNSIHQDE
3) MNYSTTSGGPRGPYRKLNNIPSHQQRHHHSQQNQQQYTQQQLQHQQNLQHIMQQHHHHQQQQAQHLQQSQGQLPMRSNMPHHQLPRATSGASGLVGGVGGGVVGGGGGVGGGPGVGGPGGAVPTSSATSRTNSIPQ
4) TDDNDIVTGGGGGNANHHHHQQVQQQQGQQGQQSQQLQSGGPI
183
246
1
604
217
290
136
646










Molecular Recognition Features






MoRF SequenceStartStop




1) DDLSGGIRKKRG
2) LQGYKRG
3) YAIKK
672
663
241
683
669
245