<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21568

Description Tbc domain-containing protein
SequenceMAQESIQDVPGIGGYSRFELELECLANPVYLNYLAQQKTLDKPDFVAYLGYLQYFKDPKYAKFLQKHWRQLDDFHSLTDLKIHVSSHKEPQITAGLRSVCWKIFLVFKTLDRSSWPTHLSQARKTYESLRSHYLRAIHNPDEFESTVDPLSELSESPWIALRADEELRAEIFQDIERCMPDNVYFRQPATQNMMLDILFVWCKMHPNIGYRQGMHEILAPVLWVVERDAMKAVDQKAGARDHILAEMMDFAYIEHDTHMLFSVIMQTAKLFYAPADTGSTTKDTPMLSRSSRIFEHYLPKVDPELHAHLVKLDIVPQIFLLRWIRLLFGREFSLDAVFDMWDALFAIDSTLELVDMISVAMLLRIRWELMAADTNEAFAFLLRYPEPATPPYTFIKDALYLRDHLTRQGGAEVVTRYGKKAPAIEPETASSPRDPSPSPSFVSSRTRNSLGSPRSFVTQQGAGFEALIQGAAKNVMDRGSQWGVGKALRDAVGEVKKNVEAYQSGASSGQVTPRSGGREFRKPAQLAAAAANGRPSLERVHSANTFKRMEELDRRNKSLAKMLEVAVGDLWEYHRERDEAQRAKKDDEKGKEAMEALSLAIAKVQFVQVYLEDSSIPLPVDEVTEQASTAQATATLASPVSQSLAQPVQAAKIPPISLTTSSQPAAPLTTISNDPSPLSSRPTSPPARALSPPSKMASTLSPRSRPHLTSSNFSWMLGEDSASSNFASGTAHSTFSSDEKRRMKGKGFLFGDDDDNEDGTNEAKRGSASVKTSAKGGKNAKGKHTPETEVEEEVIDLANMGKRGVI
Length806
PositionMiddle
OrganismStemphylium lycopersici
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Pleosporomycetidae> Pleosporales> Pleosporineae> Pleosporaceae> Stemphylium.
Aromaticity0.08
Grand average of hydropathy-0.418
Instability index53.50
Isoelectric point6.27
Molecular weight90008.01
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21568
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.58|      32|      35|     698|     731|       2
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  698-  731 (50.86/34.92)	STLSPRSRPHLTSSNFswMLGEDSA...SSNFAS.GTA
  733-  768 (46.72/25.12)	STFSSDEKRRMKGKGF..LFGDDDDnedGTNEAKrGSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.61|      16|     240|     420|     435|       3
---------------------------------------------------------------------------
  420-  435 (29.48/14.86)	KAPAIEPETASSPRDP
  652-  667 (29.13/14.60)	KIPPISLTTSSQPAAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.61|      22|      23|     178|     200|       4
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  178-  200 (37.61/31.37)	C.MPDNVYFRQpATQNMMLDILFV
  202-  224 (40.00/27.34)	CkMHPNIGYRQ.GMHEILAPVLWV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     118.04|      35|      35|     470|     504|      10
---------------------------------------------------------------------------
  442-  478 (33.75/20.13)	.....VSSRTRNSLGSPRSFVtqqgagfEALIQGAAK.NVMDR
  479-  514 (53.21/36.23)	GSQWGVGKALRDAVGEVKKNV.......EAYQSGASSgQVTPR
  517-  542 (31.07/17.92)	GREFRKPAQLAAAAANGRPSL.......ERVHS..........
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21568 with Med31 domain of Kingdom Fungi
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