<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21563
Description |
Mediator of RNA polymerase II transcription subunit 11 |
Sequence | MSTEADQQKATDANQQSEKTSEEPKTYRQIAAEHIDTLNEINHQIPKLLKYFATALSQLTNDPIPFQHDAMQCEPGTLEARKEAFRINALFCGTSCELIRQELVKQINALERYKVIPKSHPKFAVTQRQAQKGKDEESEIVDPEKDVKNGGYGEFDVGVLNARANSGQVGAEDVLDRAKAILEELQKRTGGTSSAKAFFITPISSGVVRQQPPINPAPASLHSFVFTASVEPSVRLPSHSLAFAFHCSPEFGYTTIVPLFISGFNTLSASRATSSGTQLNPNETTCPSSLKRAAISDSGVPSLMQLLSRSVKLNQTSDEGNSVRRSSMRASVSAFDGMVSQARTSTPASTSA |
Length | 352 |
Position | Head |
Organism | Stemphylium lycopersici |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Pleosporomycetidae> Pleosporales> Pleosporineae> Pleosporaceae>
Stemphylium.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.433 |
Instability index | 41.52 |
Isoelectric point | 6.67 |
Molecular weight | 38194.36 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | kinase activity GO:0016301 IEA:UniProtKB-KW
transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP21563
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 54.81| 17| 17| 73| 89| 1
---------------------------------------------------------------------------
73- 89 (29.98/16.81) CEPGTLEARKEAFR.INA
92- 109 (24.83/13.03) CGTSCELIRQELVKqINA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 43.07| 15| 19| 28| 46| 2
---------------------------------------------------------------------------
28- 46 (20.67/28.18) RQIAAehidTLNEI.NHQIP
50- 65 (22.41/16.02) KYFAT....ALSQLtNDPIP
---------------------------------------------------------------------------
|