<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21556

Description Uncharacterized protein
SequenceMTTAHRPTFDPAQGKEALRGPAYHQRLLPAYMHLKTRQPGQGGEADGPRDLRAELLAAEAAHFAKTKGVTDEARTEPVPKTKRDLEDDAEANLDAEDIEAKRRRILEETRDIDADSIGSESDSSEEESDDEEDEAAELMRELEKIKRERQEQKEKEEREREAQEQEQREYDIARGNPLLNPQDFNMKRRWDDDVVFKNQARGSEVKRGPEFVNVENPDNAYTAVGAYNLNVEATALVRAAEDLLSLTRFMKEAWLFEKLNTVGEDEHDTRRNQKLEEDVAAVKEAVQKGLLGDNDVNGEKK
Length301
PositionHead
OrganismTalaromyces amestolkiae
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Trichocomaceae> Talaromyces> Talaromyces sect. Talaromyces.
Aromaticity0.05
Grand average of hydropathy-1.156
Instability index52.31
Isoelectric point4.73
Molecular weight34271.14
Publications
PubMed=28649280

Function

Annotated function Involved in pre-mRNA splicing. 
ECO:0000256	ARBA:ARBA00003777
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
spliceosomal complex	GO:0005681	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
mRNA splicing, via spliceosome	GO:0000398	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions











Repeat regions





Repeats

>MDP21556
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.00|      27|      27|      11|      37|       1
---------------------------------------------------------------------------
   11-   37 (50.68/32.68)	PAQGKEALRGPAYHQRLLPA.YMHL.KTR
   39-   67 (39.32/23.77)	PGQGGEADGPRDLRAELLAAeAAHFaKTK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     137.50|      32|     102|      71|     102|       2
---------------------------------------------------------------------------
   71-  102 (51.28/20.56)	DEARTEPV..PK...TKRDLEDDAEANLDAEDIEAKR
  107-  138 (43.28/16.52)	EETRDIDA..DS...IGSESDSSEEESDDEEDEAAEL
  171-  207 (42.94/16.35)	DIARGNPLlnPQdfnMKRRWDDDVVFKNQARGSEVKR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21556 with Med22 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MTTAHRPTFDPAQGKEALRGPAYHQRLLPAYMHLKTRQPGQGGEADGPRDLRAELLAAEAAHFAKTKGVTDEARTEPVPKTKRDLEDDAEANLDAEDIEAKRRRILEETRDIDADSIGSESDSSEEESDDEEDEAAELMRELEKIKRERQEQKEKEEREREAQEQEQREYDIARGNPLLNPQDF
1
184










Molecular Recognition Features






MoRF SequenceStartStop




1) AELMRE
2) AKRRRILE
3) GKEALRGPAYHQRLLPAYMHLKTRQPGQG
4) GPRDLRAELLAAEAAHFAKTKGV
136
100
14
47
141
107
42
69