<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21546

Description Uncharacterized protein
SequenceMADTAPATAAPPAAATTAPAAAPSQHQFQTTTQPQASETSSAQSPNASTATATNGQSQAPAPAQFQSQTQTQTQSQAQAQAQAAQAQAQAAAAVAVVGNQSNTNGNAGIEEFPCMWQGCTERCANPETLYEHVCEKHVGRKSTNNLNLTCQWGNCRTTTVKRDHITSHIRVHVPLKPHKCELCGKAFKRPQDLKKHVKTHADDSVLIRSPGPTDVRGQEIPYGMMNNPKGFPAGAHYFEQPMNPVHAGQGYHPQAQYYQGQPHPQPPNAAYGNVYYTLNAGDNHTVYDSRKRIFDSVNAFFGDTKRRQFDPTSYAAIGQRLGGLQGLQLPLNAGPGADYHMGGGIPVGPGGGYGPALAAPAYHLPPMTNARTKSDLLDLDRMLETIHTTVYESDDHVAAAGIAQPGATYIPRMSHGGTTHQTPPITLPSSHATATTTNMSNASIIAATSPGSTPALTPPSSAVSYASSHHSPGSYSHRVSPPHDHDMAMYPRLPSTTAHEMAGGYTASANAAPPSTLSNSFEYNDRRRWMGGVLERSRPDDYAKSSIDDMLEDGERTPTRKDPLDHDSNESDDKFNHNLIDPALQQQETRSSSSPDAEAAKRAAQAATEATRRGEEEWLENVRILEQLRAYVRDRLARGDYEEEGESKSDNAASSGAASSEDDHMEGVEHTEHSHSTEERQKSEDSNPLAALKELTTSSPSSTQGLYPTLKGIEDDAESTKME
Length723
PositionTail
OrganismTalaromyces amestolkiae
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Trichocomaceae> Talaromyces> Talaromyces sect. Talaromyces.
Aromaticity0.06
Grand average of hydropathy-0.803
Instability index56.70
Isoelectric point5.77
Molecular weight77668.98
Publications
PubMed=28649280

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21546
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.65|      15|      19|     229|     247|       1
---------------------------------------------------------------------------
  229-  244 (25.52/ 9.97)	KGFPAGAHYFE.QPmNP
  249-  264 (28.13/11.10)	QGYHPQAQYYQgQP.HP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.02|      29|      30|     422|     450|       2
---------------------------------------------------------------------------
  432-  462 (42.94/17.07)	ATATTTNMSNASIIAATSP......gsT.PALTPPSSA
  463-  497 (38.05/14.32)	VSYASSHHSPGSYSHRVSPphdhdmamY.P..RLPSTT
  498-  520 (26.03/ 7.57)	AHEMAGGYT.ASANA.............aPPSTLSNS.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     165.10|      52|     249|     368|     422|       3
---------------------------------------------------------------------------
  371-  422 (93.69/41.26)	RTKSDLLDLDRMLETIHTTV........YESD.....DHVAAAGIAQPGATYIPRMSHGGTTHQT
  613-  677 (71.41/29.22)	RGEEEWLENVRILEQLRAYVrdrlargdYEEEgesksDNAASSGAASSEDDHMEGVEHTEHSHST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     136.59|      34|      34|      10|      43|       4
---------------------------------------------------------------------------
   10-   32 (34.54/12.83)	..............AP.PAAATTAPAAAPSQHQFQTTT
   33-   69 (51.69/23.00)	QPQASETSSAQspnAS.TATATNGQSQAPAPAQFQSQT
   70-   92 (23.61/ 6.35)	QTQTQSQAQAQ.....aQAAQAQAQAAA..........
  586-  607 (26.75/ 8.21)	QQETRSSSSPD...AE..AAKRAAQAA...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.17|      23|      45|     122|     146|       5
---------------------------------------------------------------------------
   98-  138 (31.48/25.66)	GNQSNTNG.......nagieefpcmwqgcteRCANPetLYEHVCE.............KHV
  139-  197 (22.68/11.56)	GRKSTNNLnltcqwgncrtttvkrdhitshiRVHVP..LKPHKCElcgkafkrpqdlkKHV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      46.65|      10|      17|     320|     330|       6
---------------------------------------------------------------------------
  320-  330 (14.86/11.21)	RLGGlQGLQLP
  340-  346 (15.68/ 6.75)	HMGG..G..IP
  356-  365 (16.11/ 7.15)	ALAA.PAYHLP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21546 with Med3 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GIAQPGATYIPRMSHGGTTHQTPPITLPSSHATATTTNMSNASIIAATSPGSTPALTPPSSAVSYASSHHSPGSYSHRVSPPHDHDMAMYPRLPSTTAHEMAGGYTASANAAPPSTLSNSFEYNDRRRWMGGVLERSRPDDYAKSSIDDMLEDGERTPTRKDPLDHDSNESDDKFNHNLIDPALQQQETRSSSSPDAEAAKRAAQAATEATRRGEEEWLE
2) MADTAPATAAPPAAATTAPAAAPSQHQFQTTTQPQASETSSAQSPNASTATATNGQSQAPAPAQFQSQTQTQTQSQAQAQAQAAQAQAQAAAAVAVVGNQSN
3) VRDRLARGDYEEEGESKSDNAASSGAASSEDDHMEGVEHTEHSHSTEERQKSEDSNPLAALKELTTSSPSSTQGLYPTLKGIEDDAESTKME
401
1
632
620
102
723










Molecular Recognition Features






MoRF SequenceStartStop




1) SNPLAALKELTTS
2) TQGLYPTLKGIEDDAESTKME
686
703
698
723