<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21537

Description mediator of RNA polymerase II transcription subunit 24 isoform X2
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDIFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHIAKLEEASSWTAIEHCLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHSEQLHKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTGELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNSAFEFLLQLTPLLDKADQRCNCDCTNFLLQECSKQGLLSEASTNNLMAKRKADREHAPQLKSDENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHRSEESTKAASVRALLFDISFLMLCHVAQTYGSEVILSESNTGGEVFFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEIKLVQMKWHEACLNISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASSRQKKRQREDIEDYISLFPLDDMQPSKLMRLLSSNEEDANILSSPTDRSMSSNLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFAQWFMEGCVDCLEQGGRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
Length989
PositionTail
OrganismLipotes vexillifer (Yangtze river dolphin)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Artiodactyla> Whippomorpha> Cetacea> Odontoceti> Lipotidae> Lipotes.
Aromaticity0.07
Grand average of hydropathy0.002
Instability index46.74
Isoelectric point6.45
Molecular weight110255.95
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21537
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.67|      47|     538|     404|     451|       1
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  404-  451 (75.46/51.21)	QPNPGLILRAEPtVTNILKTMDADHSKSPEGLLGV......LGHMLSGKSLDLL
  937-  989 (69.21/42.41)	QGGRGSILQFMP.FTTVSELVKVSAMSSPKVVLAItdlslpLGRQVAAKAIAAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     122.17|      40|     538|     177|     231|       2
---------------------------------------------------------------------------
  183-  226 (65.73/59.79)	LEEASSWtaieHCLLK.LGEILANL................SNPQLRSQAEQCGTLIRSIP
  792-  848 (56.44/23.45)	LTDSSKW....HSLMDpPGTALAKLavwcalssysshkgqaSSRQKKRQREDIEDYISLFP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     139.36|      46|     247|      78|     126|       7
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   78-  126 (73.71/63.96)	VLTAISKFD....DFSRD........LCVQALLDIMDIFCDrLSCHG.KAEECIGlcRALLS
  316-  374 (65.65/44.69)	VLVKLKKYShgdkDFTEDvnsafeflLQLTPLLDKADQRCN.CDCTNfLLQECSK..QGLLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.73|      42|     182|     704|     752|       8
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  704-  752 (65.30/64.51)	KRPIKEVLTDIFakVLEKGWVDSRSIHIfdtllHMGGVYWFCNNLIKEL
  894-  935 (75.44/53.93)	RDPLNRVLANLF..LLISSILGSRTAGP.....HTQFAQWFMEGCVDCL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21537 with Med24 domain of Kingdom Metazoa
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