<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21520

Description Mediator complex subunit 22
SequenceMAVDRSRTQLDTENHRITHHLGRLEERERKRELWVICRRPRRSRELTPERDFGLKATGPISPASAQGRCLPRLPRRVAAVRERSGDGGREPGLTGRDARSSPPRPSARRAGLCGPGGDRWPQISFPALPEAPAMAQQRALPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRALQEECDRKLIALRDEISIDLYELEEEYYSSSSSLCEANDLPLCEAYWRLDLDTDSADGLSAPVLASPEPSAGPLQAAAPAHSHATGPGPTEHA
Length333
PositionHead
OrganismFelis catus (Cat) (Felis silvestris catus)
KingdomMetazoa
Lineage
Aromaticity0.04
Grand average of hydropathy-0.734
Instability index69.88
Isoelectric point6.06
Molecular weight37143.24
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21520
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     152.40|      45|      55|      26|      78|       1
---------------------------------------------------------------------------
   26-   72 (81.26/44.51)	ER..ERKRELWVICRRPRRSRELTPERDFGLkaTGPI..............SPASAQGRCLPR
   82-  142 (71.14/26.67)	ERsgDGGREPGLTGRDARSSPPRPSARRAGL..CGPGgdrwpqisfpalpeAPAMAQQRALPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.28|      35|      55|     154|     190|       2
---------------------------------------------------------------------------
  154-  190 (53.64/44.76)	RLKDDIKS..IMDNFTEIikTAKIEDETQVSRATQGEQD
  210-  246 (54.63/38.90)	KLVSDLKQflILNDFPSV..NEAIDQRNQQLRALQEECD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21520 with Med22 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ELTPERDFGLKATGPISPASAQGRCLPRLPRRVAAVRERSGDGGREPGLTGRDARSSPPRPSARRAGLCGPG
2) GLSAPVLASPEPSAGPLQAAAPAHSHATGPGPTEHA
45
298
116
333










Molecular Recognition Features






MoRF SequenceStartStop




NANANA