<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21500

Description Uncharacterized protein
SequenceSTESAWASRSLAHSLALSLCPFLCARGGSRIVKTSSPRGEAKMSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAAAAAAAATTATAAPTAVAQQHPPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDVERGVCVHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK
Length569
PositionTail
OrganismFelis catus (Cat) (Felis silvestris catus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Carnivora> Feliformia> Felidae> Felinae> Felis.
Aromaticity0.07
Grand average of hydropathy-0.253
Instability index38.58
Isoelectric point5.78
Molecular weight61194.66
Publications
PubMed=17975172

Function

Annotated function 
GO - Cellular Component
histone deacetylase complex	GO:0000118	IBA:GO_Central

GO - Biological Function
transcription corepressor activity	GO:0003714	IBA:GO_Central

GO - Biological Process
histone deacetylation	GO:0016575	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21500
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     372.95|      40|      40|     377|     416|       1
---------------------------------------------------------------------------
  220-  249 (34.18/14.89)	..............LRGHESE...........VFICAWNPVS.........dlL.ASGS.GDSTAR
  268-  305 (42.91/20.50)	HCirEGGHDVP..S....NKD...........VTSLDWNSDG.........tlL.ATGS.YDGFAR
  306-  335 (31.31/13.05)	I...WTEDGNLASTLGQHKGP...........IFALKWNKKG..........nY............
  336-  387 (44.81/21.72)	IL..SAGVDKTTIIWDAHTGEakqqfpfhsapALDVDWQNNT..........tF.ASCS.TDMCIH
  388-  429 (63.05/33.43)	VC..RLGCDRPVKTFQGHTNE...........VNAIKWDPSG.........mlL.ASCS.DDMTLK
  430-  480 (58.94/30.79)	IW..SMKQDTCVHDLQAHSKE...........IYTIKWSPTGpatsnpnsnimL.ASAS.FDSTVR
  484-  522 (51.45/25.98)	VE..RGVC...VHTLTKHQEP...........VYSVAFSPDG..........kYlASGS.FDKCVH
  523-  564 (46.32/22.68)	IW..NTQSGSLVHSYRG.TGG...........IFEVCWNARG........dkvG.ASASdGSVCV.
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21500 with Med16 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ATAAPTAVAQQHPPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKA
167
217










Molecular Recognition Features






MoRF SequenceStartStop




NANANA