<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21497

Description Mediator of RNA polymerase II transcription subunit 13
SequenceMTAAANWVANGASLEDCHSNLFSLAELTGIKWRRYNFGGHGDCGPIISAPAQDDPILLSFIRCLQANLLCVWRRDVKPDCKELWIFWWGDEPNLVGVIHHELQVVEEGLWENGLSYECRTLLFKAIHNLLERCLMDKNFVRIGKWFVRPYEKDEKPVNKSEHLSCAFTFFLHGESNVCTSVEIAQHQPIYLINEEHIHMAQSSPAPFQVLVSPYGLNGTLTGQAYKMSDPATRKLIEEWQYFYPMVLKKKEELKEEEELGYDDDFPVAVEVIVGGVRMVYPSAFVLISQNDIPVPQSVAGAGGHITVGQQGLGSVKDPSNCGMPLTPPTSPEQAVMGESGGTQSAVSHLGSQDGGMITMHSPKRSGKIPPKLHNHMVHRVWKECILNRTQSKRSQMSTPTLEEEPANNPATWDFVDPTQRVSCSCSRHKLLKRCAVGPSRPPAASQPGFGAGPSSSSSLPPPASKHKTTERPEKGDKLQKRPLIPFHHRPSVADEFCVEQDTPGQKLGLAGIDSSLEVSSSRKYDKQMAVPSRNTSKQMNLNPMDSPHSPISPLPPTLSPQPRGQETESLDPPSVPVNPALYGNGLELQQLSTLDDRTVLVGQRLPLMAEVSETALYCGIRPLNPESSDKSWNSYRLPPVDDAEFRPPELQGERCDAKMEVNSESTALQRLLAQPNKRFKIWQEKQPQMQPLHFLDPLPLSQQPGDSLGEVNDPYTFEDGDIKYIFTANKKCKQGAEKDSLKKNKSEDGFGTKDVTTPGHSTPVPDGKNAMSIFSSATKTDVRQDSAAGRAGSSSLTQVTDLAPSLHDLDNIFDNSDDDELGAASPALRSSKMPAVGAEDRPLGKDGRAAVPYPPTVADLQRMFPTPPSLEQHPAFSPVMNYKDGISSETVTALGMMESPMVSMVSTQLTEFKMEVEDGLGSPKPEEVKDFSYVHKVPTFQPFVGSSMFAPLKMLPSQCLLPLKIPDACLFRPSWAVPPKIEQLPMPPAAIFSRDGYNNVPSVGSLADPDYLNTPQMNTPVTLNSAAPASNSGAGVLPSPATPRFSVPTPRTPRTPRTPRGGGTASGQGSVKYDSTDQGSPASTPSTTRPLNSVEPATMQPIPEAHSLYVTLILSDSVMNIFKDRNFDSCCICACNMNIKGADVGLYIPDSSNEDQYRCTCGFSAIMNRKLGYNSGLFLEDELDIFGKNSDIGQAAERRLMMCQTTFLPQVEGARKSQEPPISLLLLLQNQHTQPFASLSFLDYISSNSRQTLPCVSWSYDRVQADNNDYWTECFNALEQGRQYVDNPTGGKVDEALVRSATVHSWPHSNVLDISMLSSQDVVRMLLSLQPFLQDAIQKKRTGRTWENIQHVQGPLTWQQFHKMAGRGTYGSEESPEPLPIPTLLVGYDKDFLTISPFSLPFWERLLLDPYGGHRDVAYIVVCPENEALLEGAKTFFRDLSAVYEMCRLGQHKPICKVLRDGIMRVGKTVAQKLTDELVSEWFNQPWSSEENDNHSRLKLYAQVCRHHLAPYLATLQLDGSLLIPPKYQSPPAAAQGQATPGNAGPLASNSGSAAPSAGSAFNPTSSSSSGNPAAGSSASGSSVPPVSASAPAPAPVVNQISTTSSSGFSASVGGQNPGSGAGSADRTQGSAGCGGDPEPGQSSSQPSQDGQESVTERERIGIPTEPDSADSQAYPPAVVIYMVDPFTYTADEDSTSGNFWLLSLMRCYTEMLDNLPEHMRNSFILQIVPCQYMLQTMKDEQVFYIQYLKSMAFSVYCQCRRPLPTQIHIKSLTGFGPAASIEMTLKNPERPSPIQLYSPPFILAPIKDKQTELGETFGEASQKYNVLFVGYCLSHDQRWLLASCTDLHGELLETCIVNIALPNRSRRSKVSARKIGLQKLWEWCIGIVQMTSLPWRVVIGRLGRLGHGELKDWSILLGECSLQTISKRLKDVCRMCGISAADSPSILSACLVAMEPQGSFVVMPDAVTMGSVFGRSTALNMQSSQLNTPQDASCTHILVFPTSSTIQVAPANYPNEDGFSPNNDDMFVDLPFPDDMDNDIGILMTGNLHSSPNSSPVPSPGSPSGIGVGSHFQHSRSQGERLLSREAPEELKQQPLALGYFVSTAKAENLPQWFWSSCPQAQNQCPLFLKVRFGAVQRSVLAHVQSGHPGPHLLPSRPLCGAHSVVQRHHEHTLIGEALVLSGSVPPPCSLSPRNLLHSARAPHALLERPLSTVLHCDYSSAGTCHFCSVHYQSDALTLLSWTWKLP
Length2248
PositionMiddle
OrganismFelis catus (Cat) (Felis silvestris catus)
KingdomMetazoa
Lineage
Aromaticity0.07
Grand average of hydropathy-0.365
Instability index57.21
Isoelectric point5.80
Molecular weight245800.48
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21497
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     113.00|      28|      28|    1033|    1060|       1
---------------------------------------------------------------------------
  973- 1002 (25.18/ 8.58)	..PSWAVP.PKIEQLPmppaaiFS........RDGYNNVPS.
 1007- 1040 (38.15/17.62)	ADPDY.LNTPQM.NTP......VTlnsaapasNSGAGVLPSP
 1041- 1068 (49.68/25.66)	ATPRFSVPTPRTPRTP......RT........PRGGGTASGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.69|      27|      29|    1856|    1884|       2
---------------------------------------------------------------------------
 1856- 1884 (44.42/31.29)	C..IVNI.ALPNRSRRSKVSarKIGLQKLWEW
 1885- 1914 (42.27/23.71)	CigIVQMtSLPWRVVIGRLG..RLGHGELKDW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      73.42|      16|      19|    1614|    1630|       3
---------------------------------------------------------------------------
 1563- 1576 (20.51/ 6.57)	...NPTSSSSSGNPAA.G
 1614- 1630 (26.07/16.20)	GGqNPGSGAGSADRTQ.G
 1635- 1651 (26.84/11.89)	GG.DPEPGQSSSQPSQdG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.86|      27|      28|    2072|    2099|       4
---------------------------------------------------------------------------
 2072- 2099 (41.86/33.56)	HFQhSRSQGERL...LSREAPEELKQQPLAL
 2101- 2130 (46.00/31.15)	YFV.STAKAENLpqwFWSSCPQAQNQCPLFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.55|      25|      28|    1126|    1150|       5
---------------------------------------------------------------------------
 1126- 1150 (51.64/31.43)	NFDSC.CICACN..MNIK.GADVGLYIPD
 1153- 1181 (36.91/20.38)	NEDQYrCTCGFSaiMNRKlGYNSGLFLED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.82|      27|      57|    1524|    1555|       6
---------------------------------------------------------------------------
 1524- 1555 (45.61/30.81)	IPPKYQSPPAAAqgqatP.GNAGPLASNSGSAA
 1584- 1611 (45.21/21.29)	VPPVSASAPAPA.....PvVNQISTTSSSGFSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.69|      12|      28|     542|     553|       7
---------------------------------------------------------------------------
  542-  553 (24.80/14.12)	NPMDSPHSPISP
  568-  579 (22.89/12.21)	ESLDPPSVPVNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.37|      18|      28|    2021|    2043|       8
---------------------------------------------------------------------------
 2021- 2043 (25.52/22.75)	SPNNDdmfvDLPFPDDmDNDIGI
 2052- 2069 (34.86/15.45)	SPNSS....PVPSPGS.PSGIGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     141.09|      36|      56|     865|     900|       9
---------------------------------------------------------------------------
  756-  793 (24.76/ 7.79)	.TTPG...HS..TPVPDGKNAMsifSSATKTdvrqdsAAGRAGS.
  865-  900 (65.66/33.44)	PTPPSLEQHPAFSPVMNYKDGI...SSETVT......ALGMMESP
  923-  956 (50.67/24.04)	PKPEEVKDFSYVHKVPTFQPFV...GSSMFA......PLKML..P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.60|      19|      27|    1742|    1768|      10
---------------------------------------------------------------------------
 1731- 1752 (26.25/19.11)	CQYMLQTMKDEQvfyIQYLKSM
 1758- 1776 (35.35/29.77)	CQCRRPLPTQIH...IKSLTGF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.95|      25|      27|      60|      84|      12
---------------------------------------------------------------------------
   60-   84 (48.05/34.53)	FIRCLQANLLCVWRRDVKPDCKELW
   86-  110 (47.90/34.40)	FWWGDEPNLVGVIHHELQVVEEGLW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.01|      26|      28|     363|     390|      13
---------------------------------------------------------------------------
  363-  390 (43.33/33.78)	KRSGKIPPKLHNHMVHR..VWKecILNRTQ
  392-  419 (42.69/25.64)	KRSQMSTPTLEEEPANNpaTWD..FVDPTQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.84|      15|      18|     596|     613|      14
---------------------------------------------------------------------------
  598-  613 (21.25/18.05)	TVLVGQRlPLMAEVSE
  615-  629 (28.59/11.88)	ALYCGIR.PLNPESSD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.36|      14|      20|    1375|    1388|      15
---------------------------------------------------------------------------
 1375- 1388 (27.65/13.96)	SPEPLPI..PTLLVGY
 1396- 1411 (21.71/ 9.16)	SPFSLPFweRLLLDPY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.27|      32|    1265|     156|     189|      16
---------------------------------------------------------------------------
  156-  189 (52.23/39.17)	PVNKSeHLSCAFTFFlHGESNVCTSVEIAQHQPI
 1424- 1455 (59.04/35.46)	PENEA.LLEGAKTFF.RDLSAVYEMCRLGQHKPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.61|      18|      27|     461|     478|      17
---------------------------------------------------------------------------
  461-  478 (31.61/18.00)	PPASKHKTTERPEKGDKL
  490-  507 (32.00/18.32)	PSVADEFCVEQDTPGQKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      75.90|      17|      17|    1232|    1248|      22
---------------------------------------------------------------------------
 1207- 1223 (25.78/11.35)	FLPQVEGARKS..QEPPIS
 1224- 1240 (25.13/10.86)	LLLLLQNQHTQ..PFASLS
 1241- 1259 (24.99/10.76)	FLDYISSNSRQtlPCVSWS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.41|      14|      17|     225|     240|      23
---------------------------------------------------------------------------
  225-  238 (24.00/22.81)	YKMSDPATRKLIEE
  243-  256 (23.41/10.97)	YPMVLKKKEELKEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.85|      11|      21|     817|     827|      25
---------------------------------------------------------------------------
  817-  827 (18.95/ 9.12)	DDDELGAASPA
  839-  849 (19.90/ 9.96)	EDRPLGKDGRA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21497 with Med13 domain of Kingdom Metazoa
Unable to open file!