<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21417

Description Uncharacterized protein
SequenceMASTPTQLLGGRPLGSPASAPGSSGHAREQPAAAASDPPLEPYQQQPPDWRPSLHPKAPQHPVPDLFPTAPGQPEDDMSQISVRKGFVGRAYVRNESFSAHEMIHERLASKNLLPTLSEWFDEVLLRRAELHRNSIAPSQYKPPSRVTLNEAKLANYVKDLADPNVPLARLSRNVPHGFRGEKLFEMLWAGGALPAASATPFGPTASSSSAPTHGTAGLPASASTTGRTSVEVSRAVWFIRALGAAELSSLRNKSAASVIPETTSNLCSWMAKQLAELNLVQVPESSNTAAPSPATPSAAFPQPRTPSSASILHRRSFHITRTPSGLHPASSPVAASVPGEAATGAVREVCSTLQNEVDEARWIAKWSYSLSLARHLQAQQLLDRSVLVRWIVEAFATSNLVQLPFMLELVHEVLVLMLQRRHLVRPFLTALLHQIPALDARLDRRSSGELRSKLVRLVRVVCESDPDLLVAPRLWYDHAATLTQLLSETDTGDHGASSSVYLVTPEYLERHVRPRAERLLLKRLLSIEQHTKMGQGLSNAPAQVYPASALHADIVALDSFDMKEIDRVFLQALYSANQLPSRKTKAIFDDAAWTPRIETILTWACTDLRAGIARQYLAATLIEKIRFGVAWDEISEGSDNNSLRAFDLDHHSRKARRINVEPMLIKWLSDVESAIGLADAVATTTASAAMPDARTSRLASVDVACVVILVGELARRGIFSYTKYLQRLIARGMTTNTTPVSDAADPLDAVATDTRIEQTPKDSLHLRLLRSLPLYDQPASVYQQRRQAIYGDRSKETYEEAAERRALRQLKAFLPGVFAAEPEPSDQPRGPGHNTAAEEVVETADKARRLEDQLGRLWSASRYVRCKLFRNELLTAAFARAEALTGQDLCRIAAILERGQDFEAMAQLIAALLLRPLSDGLARSTFNLVLEFACIWRSMDIMGTLNQLVRQQLNHSSSVRNDKQAVMASTALLRLRTLMEGTSGRVTAPVSSELATQIVILQHVASIRSRVDALLHTISNADPRLANFEAAERLNNFRSLIIQPDAMTDEIVERAIVESVYESSDTITVSVAARLIEQLYLEASLEIDDRHARWLGHLAARIEQSSAVGQSAGAGSARPLYELLRRLVAQGTLNLQVAMDHLLLPCTFNMVKRMTDPASRSAEPVPRLLELVELLATLFAGVCGVEDDASWQDSRALTSQAMLLLAPANLPGLLKIAVCLICASDEGSPVDTAQRQSLDRFWKGLLGSESMQLAFRSDPRRVLLSLREASRGMWGINVHRVTDLAIGCLAPTSLLLKEAGSIDATAIKQRLDGWNTSMTAVELVEIFERLSVVESSFQARADSKTKSLAAGIFGDIFVTHPNIGPQFLRDSQSVGLASKFADVGLKSLAEATRRQAELLRAEREREAPDTKQAHETSTQATDSAEGSIAKATEENGSAGDAGTAPRRSPELTAVEDEIKTLFRSLLRLCEHQGSFTFTATDAESCARILHQIVLTLESGVGSIKDDAHAYRALAELFQEPLTLDLLCLILRFNCLWSANMKTISTRLVRALLKLAREAGKTVELGSLFVVLLDTIGFVIDELPLVLLTACIPEVEEQIQQPGELATFPRTARWTRFSFNLEGAYGDTGQFTASSAGAALKRGWFTPGGLNPWECPEYLDPAPVPAAATTGAMGSGTQGATAIGAARLASRAVAGSVTFGTNRSGVDGDPGFSTSGLPGAKAGWPFKLVLNSAIPASLLGMRLTRDLVPQYTSPSSPGVVSTPSTDTSHGQQTGHAAAAIPLPAFLESELSYGDRMAGESRFARDLRRGLLPNKRQRL
Length1818
PositionKinase
OrganismTesticularia cyperi
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Ustilaginomycetes> Ustilaginales> Anthracoideaceae> Testicularia.
Aromaticity0.06
Grand average of hydropathy-0.129
Instability index48.33
Isoelectric point6.66
Molecular weight197713.78
Publications
PubMed=29771364

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21417
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     259.15|      73|     675|     858|     936|       1
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  858-  936 (108.48/86.41)	LWSAS.RYVRCKLFRNELLTAAFARaEAltGqdLCRIAAiLERGQDFEAMAQLIAALLLRPLS.DGLARSTFNLVLEFACI
 1174- 1223 (64.81/36.42)	................ELLATLFA......G..VCGVED.DASWQDSRALTSQ.AMLLLAPANlPGLLKIAVCLI....C.
 1536- 1592 (85.85/50.98)	LWSANmKTISTRLVRALL...KLAR.EA...............GKTVE.LGSLFVVLL...DT.IGFVIDELPLVLLTACI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.17|      40|      40|     767|     806|       2
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  767-  806 (67.42/43.17)	LRLLRS.LP.LYDQPASVYQQRRQAIYGDRSKETYEEAAERR
  808-  849 (58.75/36.53)	LRQLKAfLPgVFAAEPEPSDQPRGPGHNTAAEEVVETADKAR
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     235.19|      81|     671|     559|     649|       3
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  559-  649 (122.38/91.50)	DSFDMKEIDRvFLQALYSAN..QL.....PSRKTKAIFDDA..AWTPRIETIltwacTDLRAGIarqyLAAT.LIEKIRFGVAWDEISEGSD..NNSLRAFDL
 1232- 1324 (112.81/62.67)	DTAQRQSLDR.FWKGLLGSEsmQLafrsdPRRVLLSLREASrgMWGINVHRV.....TDLAIGC....LAPTsLLLKEAGSIDATAIKQRLDgwNTSMTAVEL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     256.10|      75|     270|    1051|    1126|       4
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 1051- 1126 (119.34/95.21)	EIVER.AIVESVYES.SDTITVSVAARLIEQLYLEASlEIDD...RHARWLGHLAARI......EQSSAVGQSAGAGSARPLYELLR
 1326- 1401 (100.73/74.62)	EIFERlSVVESSFQArADSKTKSLAAGIFGDIFVTHP.NIGPqflRDSQSVG.LASKF.........ADVGLKSLAEATRRQAELLR
 1766- 1808 (36.04/19.97)	........................................DT...SHGQQTGHAAAAIplpaflESELSYGDRM.AGESRFARDLRR
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     216.55|      49|     270|      18|      68|       5
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   18-   68 (84.33/50.62)	ASAPGSSGHAREQPAAAASDPPLEPYQQQPPDWRPSLHPKAPqhPV...PDLFP
  291-  339 (87.85/47.07)	APSPATPSAAFPQPRTPSSASILHRRSFHITRTPSGLHPASS..PV...AASVP
 1632- 1665 (44.38/19.48)	...............TASSAGAALKRGWF...TPGGLNPWEC..PEyldPAPVP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.73|      16|      20|     401|     417|       6
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  401-  417 (23.40/19.69)	LVQlPFMLELVHEVLVL
  424-  439 (28.33/18.74)	LVR.PFLTALLHQIPAL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.95|      41|     286|     168|     210|       7
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  169-  210 (70.74/46.08)	ARLSRNVPHGFRGeKLFEM................LW...AGGALPAASATPFGPTASSSS
  441-  500 (54.21/26.37)	ARLDRRSSGELRS.KLVRLvrvvcesdpdllvaprLWydhAATLTQLLSETDTGDHGASSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.98|      30|     267|    1421|    1450|      10
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 1421- 1450 (50.61/30.96)	ATDSAEGSIAKATEENGSAGDAGTAPRRSP
 1689- 1718 (52.37/32.32)	ASRAVAGSVTFGTNRSGVDGDPGFSTSGLP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21417 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AELLRAEREREAPDTKQAHETSTQATDSAEGSIAKATEENGSAGDAGTAPRRSPE
2) MASTPTQLLGGRPLGSPASAPGSSGHAREQPAAAASDPPLEPYQQQPPDWRPSLHPKAPQHPVPDLFPTAPGQPEDDMSQISVR
1397
1
1451
84










Molecular Recognition Features






MoRF SequenceStartStop




1) QLLGG
7
11