<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21410

Description Kinase-like protein
SequenceMDAFGTDPSATDHRSAMSLDHLESIGDLAASTSSDAMNGYNSQANDGFAASTSAAPSRTFPDAPLRPAGYFYSDEQDPHAASFWTQFNDPHDLAARHIPTDSSAAAAMKAYREYRDRARKPVLATYTILGFLSSGTYGRVYKARLRAAPNQSSSQMPLGMEGQVSRKRAYNMLDSPAGSAGGGGGGGAAGASGHAGSVHGNTPRSLTAVLESHANNDSNSPRNVASPGATNYQQLHQHHSGSANDGQIYAIKKFKPDTKETDPSIYTGISQSAMREISLNRELKHVNIVTLHQVMLEEKAIYMVFEYAEHDLLQIIHHHSTVLRTPIPTPVLKSLLWQLINGVAYLHANWILHRDLKPANILVTSRGVVKIGDLGLARLYSAPLQSLYNGDKVVVTIWYRAPELLLGARHYTTAIDMWSVGCIWGELLALRPMFKGEEAKMDPKTKAAPFQTDQLKRIVEVLGTPNKDRWPAIESMPDYKGWWPHLRLDNYPKNLTRWYTSRNKSEDGYNLFDSLLQYDPIKRLTAQQALQHSWFTESEPRPTANAFVSLPKPESTYPNRRVIHDDLDPKMRSNYLPPIESHHLINNGANNPASSHSLQHGYGPSLQQQSQQLSRTAGTGGGQFPPSSLLRNPIVVGSSGIGSAKAINIGSAGTGGAGGAGGAGGAGGAAAGGGLNPTSGIGGPAAPPPITIGTGSALPLPFNTSTGPATLPTAPPSVQSVQSITNDLGLGGGAGAGGDRDRDRERDRDRDRDGRGGGIGIGIGIAGIDDSLFQLQSASNSSSVASNTSQSHQPQHQLSGSTTNTTTTNTNSSSKNNLVATATRNQQRKRQKI
Length833
PositionKinase
OrganismTesticularia cyperi
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Ustilaginomycetes> Ustilaginales> Anthracoideaceae> Testicularia.
Aromaticity0.07
Grand average of hydropathy-0.515
Instability index48.04
Isoelectric point9.10
Molecular weight89011.96
Publications
PubMed=29771364

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP21410
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.34|      18|      24|     672|     692|       1
---------------------------------------------------------------------------
  648-  666 (26.13/ 7.89)	NIGSAGtGG...AGGAGGAGGA
  667-  687 (27.21/15.32)	GGAAAG.GGlnpTSGIGGPAAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.97|      15|      16|     189|     204|       3
---------------------------------------------------------------------------
  189-  204 (24.62/14.47)	AGASGHAGSvHGNTPR
  208-  222 (25.35/10.97)	AVLESHANN.DSNSPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.45|      17|      17|      17|      33|       4
---------------------------------------------------------------------------
   17-   33 (27.50/17.08)	MSLDHLESIGDLAASTS
   37-   53 (28.95/18.41)	MNGYNSQANDGFAASTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.43|      21|      90|     601|     628|       5
---------------------------------------------------------------------------
  575-  595 (39.75/15.72)	YLPPI..ESHHLI....NNGANNPASS
  602-  628 (29.68/22.42)	YGPSLqqQSQQLSrtagTGGGQFPPSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.23|      16|      21|     142|     162|       6
---------------------------------------------------------------------------
  142-  162 (19.66/26.11)	KARlraAPNQSSSqmPLGMEG
  166-  181 (29.57/18.03)	RKR...AYNMLDS..PAGSAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.20|      17|      21|     774|     791|       7
---------------------------------------------------------------------------
  774-  791 (23.13/18.83)	QLqSASNSSSVASNTSQS
  797-  813 (29.07/18.58)	QL.SGSTTNTTTTNTNSS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP21410 with CDK8 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AINIGSAGTGGAGGAGGAGGAGGAAAGGGLNPTSGIGGPAAPPPITIGTGSALPLPFNTSTGPATLPTAPPSVQSVQSITNDLGLGGGAGAGGDRDRDRERDRDRDRDGRGGGIGIGI
2) KARLRAAPNQSSSQMPLGMEGQVSRKRAYNMLDSPAGSAGGGGGGGAAGASGHAGSVHGNTPRSLTAVLESHANNDSNSPRNVASPGATNYQQLHQHHSGS
3) LFQLQSASNSSSVASNTSQSHQPQHQLSGSTTNTTTTNTNSSSKNNLVATATRNQQRKRQKI
4) YPNRRVIHDDLDPKMRSNYLPPIESHHLINNGANNPASSHSLQHGYGPSLQQQSQQLSRTAGTGGGQFPPSSLLRNP
646
142
772
557
763
242
833
633

Molecular Recognition Features

MoRF SequenceStartStop
NANANA