<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21372

Description Uncharacterized protein
SequenceMNPANFSNVGGGMNGGVRPHNQMQLQQKQSETNQVILNQVGQALQAQGQYSGWRADVNIKERAVKVYQMLTSLRLIQPRIDIQHAAHAALTFEQKAFKDAREKVDYERECNEKLHHIRDTRARQAAVMQGGIMPQGPAAGMPGVGQSPYPPRMNQSVPASQMSGQQQMQMGMGDLTQQAAMQQRQQSQQQHQNMLQQQQQQQPQQPQPQQQRPQQRPGNGSALSDDLNTLSAQEYDQVCRVANQIISKTPQEDLEKIKVNLQNMTPEQRGYLARKNMDPITYFFRSQALNQLRRHKRSRMEMARAPGTGVDPNSAIMGDPMHPQRQMFQNMMNLQRNSFSMGGQQNLDPSSFIGNVENIQGQQADGLRSQEAGQLVVPASSSQMNQPPFTTQQNMFPVGGQLGQNAQGNMNGSGISPQFIAQQHAQNAQNMQQDRPQQASQFPAQPQAQNQSAQDQARVQAAAKVQFAMSHQNQPNARMQHQMTQQSPAMPMLNRPMAPGQMSPAQVAAQVRPPSRPPGMGQPPASAQTMNGQTPIPRPQIPPNLPPAVQEQLNSMSNEQLSMVLLNNQRRAMANNQAALARANASQQSMPMQQNLSQSGQGQQMVNGQMMNGQMGNGQNLRAMNLQQIAGMAGAQQPNQMLPNQMSVQQRQQQQQQQRQQDAYKLQILRQHGGGGGPEMSQEQVKEMDRLNFPPAVLNSSNPSVAAVPKNLRSWGQLKQWVASNPQPMGGLDLGKLIALQRIHLLQIASQSKDAGRNPEQGSWMPMQFQGQPQPLMNPQLQAGQQQMPVNMPPVRSITAQELQLARVRLGSQAQNISDEQLRDLIMKNRQRQMHMARQAHVQQQALVAQQQAQQAQQAQPAPQAPVTVPPNMPEIKQESQPPQLTAPQTQQSLTTKAQAQPVPPVKSAKGPPAKQAPKRKLQNDEPAESQSTTPTQKPNQPATSQPGPVPAQARSNIPFTREQLASMSPQQRAAFEAHLRRQQLQGRGSVNRASAEESWNNLPEKIRQVYNELSKTLPQAEPVPITSEQKAAMSQQIRDTTDYLGRMDALVQFIAKVPGQERNVRSLLQMRVLLMRQFKAGPDWALNDQITVTPDYFTGTTNYIKRLFHHMIARVNQQQNQPQGQRPGVAQGAPVPQATQPNMPALNASNLQQLQQQEEALQRARRASSQTVSGAAAIPQAPFGAPSPQGVPHAYGPASMPPEQLKLPPPKKRKQSHAGALPASGTPVSKTQSSKPADFKSTGVAPGGAFKCGVPDCQNHYQGFATQNALDKHVEEAHKVEEPIDNPLEFALESFRNSLIKEEDRNELQGMKGIPQASGKPGTTSSPSKNEIKLEGATPVLGSATPMARAASQLGPKPGSPTLNQQLTPRTSAGKAPTSSPLKPTTAKDGKKEPVKPTEPGQASGDAVARDPWADSAVSLEAIQETFLDFGDEGGLGFGAMDEFLNPEMFTNNQAKDTPDSVETGLVTQTPKDSELPKLDDLNGKKGDMTDDNWIPADWISFPGRPEDGFLMNDSWEDFDWDMVDRKDGAINVDDSAIAICAI
Length1544
PositionTail
OrganismAspergillus heteromorphus CBS 117.55
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
Aromaticity0.04
Grand average of hydropathy-0.839
Instability index63.42
Isoelectric point9.46
Molecular weight169394.56
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21372
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|    1798.00|     407|     456|     133|     588|       2
---------------------------------------------------------------------------
   13-  416 (534.70/142.46)	...................................MNGGV..RPHNQMQLQQKQSE.TNQVILNQVgqalQAQGQYS.GWR..ADVNIKERAVKVYQMLTSL..R..LIQ......PRIDIQHAAHAALtfeqkafkdaREKVDyeR...ECNEKLHHI.....RDTRA.......RQAAVMQggiM........PQGPAAGMPGVGQSPYPP..RM.NQSVPA.SQ.....MSGQQQMQMGMGDLTQQAAMQQR....QQSQQQHQNMLQQQQQQQPQQPQPQQQR......PQQ..RPG..NGSALS.......DDLNTLSAqeydqVCRVANQIISktpqedlekikvnlqnmtpEQRGYLA..RKNMDPITYFFRSQALNQLRRHKRSRMEMARAPGTGVDPnsaiMGDPMHPQRQMFQNMMNLQRNSFSMGGQQNLD......PSSFIGNVENI.............QGQQADGLRSQ.EAGQLVVPaSSSQMNQPPFTTqQNMFPVGGQLGQNAQGNMNGSGIS
  436-  811 (576.78/131.72)	PQQASQFPAQPQAQNQSAQDQAR..VQAAAKVQFAMSHQN..QPNARMQHQMTQQS.PAMPMLNRP....MAPGQMS.PAQVAAQVRPPSRPPGMGQPPASA..Q..TMNGQT.PIPRPQIPPNLPPAV..........QEQLN..S...MSNEQLSMVLLNNQRRAMANNQAALARANASQQ..sM........PMQQNLSQSGQGQ.......QMvNGQMMN.GQ.....MGNGQNLR.AM.NLQQIAGMAGA....QQPNQMLPNQMSVQQRQQQQQQQRQQDAyklqilRQH..GGG..GGPEMSqeqvkemDRLNFPPA.....VLNSSNPSVA..........................avPKNL.......RSW..GQLKQWVASNPQ....PMGGLD.....LGKLIALQR.....IHLLQIASQSKDAGRNPE......QGSWMP..MQF.............QGQPQPLMNPQlQAGQ.....Q..QM...PV....NMPPVRSITAQELQLARVRLG..
  812- 1169 (463.76/104.38)	....SQ......AQNIS.DEQLRdlIMKNRQRQMHMARQAhvQQQALVAQQQAQQAqQAQPA...P....QAPVTVP.PN..MPEIKQESQPPQLT.APQTQ..QslTTKAQAqPVP.PVKSAKGPPAK..........Q......................APKRKLQNDEPAESQSTTPTQ...K........PNQPATSQPG....PVPA..QA.RSNIPF.TReqlasMSPQQRAAF.EAHLRRQ.QLQGRgsvnRASAEESWNNLPEKIRQ..VYNELSKTL......PQA..EP....VPITS.................................................EQKAAMS..QQIRDTTDYLGRMDALVQF.........IAKVPGQERNV............RSLLQMRVLLMRQ.FKAGPDWALNdqitvtPDYFTGTTNYIkrlfhhmiarvnqQQNQPQGQRPG.VAQGAPVP.QATQPNMPALNA.SNL....QQLQQQEEALQRARRAS
 1170- 1412 (222.75/43.17)	SQTVSGAAAIPQAPFGAPSPQGV..PHAYGPASMPPEQLK..LPPPKKRKQ..SHA.GALPASGTP....VSKTQSSkPADFKSTGVAPGGAFKCGVPDCQNhyQ..GFATQN.ALDK.HVEE..AHKV..........EEPID..NpleFALESFRNSLIKEEDRN....................elqgmkgiPQ..ASGKPGTTSSPSKNeiKL.EGATPVlGS.....ATPMARAASQLGPKPGSPTLNQ.....QLTPRTSAGKAPTSSPLKPTTAKDGKKE......PVKptEPGqaSGDAVA.......RD....................................................................................................................................................................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.91|      13|      17|    1421|    1434|       3
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 1421- 1434 (18.49/17.80)	LEAIQEtFLD...FGDE
 1439- 1454 (19.42/12.43)	FGAMDE.FLNpemFTNN
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.87|      18|      19|    1483|    1500|       4
---------------------------------------------------------------------------
 1483- 1500 (36.92/21.19)	LNGKKGD..MTDDNWIPADW
 1503- 1522 (31.95/17.36)	FPGRPEDgfLMNDSWEDFDW
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21372 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AREKVDYERECNEKLHHIRDTRARQAAVMQGGIMPQGPAAGMPGVGQSPYPPRMNQSVPASQMSGQQQMQMGMGDLTQQAAMQQRQQSQQQHQNMLQQQQQQQPQQPQPQQQRPQQRPGNGSALSDDLNTLSAQE
2) FFRSQALNQLRRHKRSRMEMARAPGTGVDPNSAIMGDPMHPQRQMFQNMMNLQRNSFSMGGQQNLDPSSFIGNVENIQGQQADGLRSQEAGQLVVPASSSQMNQPPFTTQQNMFPVGGQLGQNAQGNMNGSGISPQFIAQQHAQNAQNMQQDRPQQASQFPAQPQAQNQSAQDQARVQAAAKVQFAMSHQNQPNARMQHQMTQQSPAMPMLNRPMAPGQMSPAQVAAQVRPPSRPPGMGQPPASAQTMNGQTPIPRPQIPPNLPPAVQEQLNSMSNEQLSMVLLNNQRRAMANNQAALARANASQQSMPMQQNLSQSGQGQQMVNGQMMNGQMGNGQNLRAMNLQQIAGMAGAQQPNQMLPNQMSVQQRQQQQQQQRQQDAYKLQILRQHGGGGGPEMSQEQVKEMDRLNFPPAVLNSSNPSVA
3) IASQSKDAGRNPEQGSWMPMQFQGQPQPLMNPQLQAGQQQMPVNMPPVRSIT
4) MDEFLNPEMFTNNQAKDTPDSVETGLVTQTPKDSELPKLDDLNGKKGD
5) MIARVNQQQNQPQGQRPGVAQGAPVPQATQPNMPALNASNLQQLQQQEEALQRARRASSQTVSGAAAIPQAPFGAPSPQGVPHAYGPASMPPEQLKLPPPKKRKQSHAGALPASGTPVSKTQSSKPADFKSTGVAPGGAFKC
6) MNPANFSNVGGGMNGGVRPHNQMQLQQKQSET
7) VCRVANQIISKTPQEDLEKIKVNLQNMTPEQRGYLARKNM
8) VRLGSQAQNISDEQLRDLIMKNRQRQMHMARQAHVQQQALVAQQQAQQAQQAQPAPQAPVTVPPNMPEIKQESQPPQLTAPQTQQSLTTKAQAQPVPPVKSAKGPPAKQAPKRKLQNDEPAESQSTTPTQKPNQPATSQPGPVPAQARSNIPFTREQLASMSPQQRAAFEAHLRRQQLQGRGSVNRASAEESWNNLPEK
9) YNELSKTLPQAEPVPITSEQKAAMSQQIRD
10) YQGFATQNALDKHVEEAHKVEEPIDNPLEFALESFRNSLIKEEDRNELQGMKGIPQASGKPGTTSSPSKNEIKLEGATPVLGSATPMARAASQLGPKPGSPTLNQQLTPRTSAGKAPTSSPLKPTTAKDGKKEPVKPTEPGQASGDAVARDPWADS
100
283
748
1442
1112
1
238
808
1011
1262
234
706
799
1489
1253
32
277
1006
1040
1417










Molecular Recognition Features






MoRF SequenceStartStop




1) AYKLQILR
2) NWIPADWISF
663
1494
670
1503