Description | Mediator of RNA polymerase II transcription subunit 4 |
Sequence | MNAIVQKSFDNLETSLATLVESVASYNPSPAAARAVIAADDGLVESLDQLGEHQQGYQKILALREVSETLDKQLIGLLEGLSEARKELSRVPGTVFEESHGAVPYDELLTYARKISKYTRPPQSSKFTQADPSGSGGDKPEQNNGEASQQSQRSLPLGLSEEDVSALDPSSQLQFTPWPSEEVMKRGALSQMGYEEELKAKGLPLPVMAPVANGQGLGDNRGPVESSMETTVAAPVQVAAAQHHRPAQKVELDLFNPDDE |
Length | 260 |
Position | Middle |
Organism | Tuber magnatum (white Piedmont truffle) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Pezizomycetes> Pezizales> Tuberaceae> Tuber. |
Aromaticity | 0.05 |
Grand average of hydropathy | -0.520 |
Instability index | 51.80 |
Isoelectric point | 4.64 |
Molecular weight | 27980.74 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364141 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP21340 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 83.71| 27| 29| 26| 54| 1 --------------------------------------------------------------------------- 26- 52 (43.49/26.85) YNPSPAAARAVIAADDGLVESLDQLGE 57- 83 (40.22/18.65) YQKILALREVSETLDKQLIGLLEGLSE --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) APVQVAAAQHHRPAQKVELDLFNPDD 2) LQFTPW 3) YDELLTYARKISKY | 234 173 105 | 259 178 118 |
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