<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21333

Description Uncharacterized protein
SequenceMASNYWLSSQCNHWLFTRAQLATARAEDERYAEHPDEVAAIGVWACNMIATLTKRLNLRQRVTATASIYFRRFYARSANAYAATDPALVATACVYVAAKVEETPVHVRSVIAEAHKIWTELGHPDFPSDVAALAEMEFYLFEELDFHLIVHHPYRALLAISGSVGKAALLRADKAAGVGLGLGIPGLNETSFGSGNGGGVDLEMASATAAAAGLDEEQAKAWEADRAALTRGDDGQPLARLEELEEAALQFAWFVLNDTYRADISLLYPPHLIAIAALYLGLLLHPTSRQRMSKSVQLMASRRDKWRHACEEHAVRSAAAGQAHAAAASGSRRAGNGVPPGGGSAQSPQYAYTPSASHASPAPGSSSLRGLASLPMRPAHLPVRPGGVAATSTPSTPFPQQHGAGTTPRSAGGAAYSLDSPGASSAVSTPPDSSAMPSGAPAPAELPRVAPLPPPPAPPPDALTFLAGLNVDIRQIAEIVQDILGMYELWHRLDAPPAESESKPSGASAAAGPAFGATPAGGMISDGSGMLQRIERMRERRRTELLMLAAAGGGAIPNKPSTR
Length563
PositionKinase
OrganismTilletiopsis washingtonensis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Exobasidiomycetes> Entylomatales> Entylomatales incertae sedis> Tilletiopsis.
Aromaticity0.06
Grand average of hydropathy-0.140
Instability index54.17
Isoelectric point6.39
Molecular weight59104.04
Publications
PubMed=29771364

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP21333
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     207.97|      37|      43|     334|     375|       1
---------------------------------------------------------------------------
  339-  375 (69.28/31.76)	PPGGGSAQSPQYAYTPSASHASP..APGSSSLRGLA.SLP
  384-  418 (47.63/16.95)	RPGGVAATSTPSTPFPQQHGAGT..TPRSAG..GAAySL.
  420-  453 (51.67/16.97)	SPGASSAVS...T..PPDSSAMPsgAPAPAELPRVA.PLP
  504-  532 (39.40/12.41)	PSGASAAAGPAFGATPAGGMIS....DGSGMLQ.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.02|      34|      50|      24|      66|       2
---------------------------------------------------------------------------
   24-   61 (53.44/31.23)	ARAEDERYAEHPDEVAAigvwACNMIATLTKRLNLRQR
   75-  108 (55.59/27.95)	ARSANAYAATDPALVAT....ACVYVAAKVEETPVHVR
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP21333 with CycC domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) SAAAGQAHAAAASGSRRAGNGVPPGGGSAQSPQYAYTPSASHASPAPGSSSLRGLASLPMRPAHLPVRPGGVAATSTPSTPFPQQHGAGTTPRSAGGAAYSLDSPGASSAVSTPPDSSAMPSGAPAPAELPRVAPLPPPPAPPPDALTF
2) WHRLDAPPAESESKPSGASAAAGPAFGATPAGGMISDGSGMLQRIERM
317
490
465
537

Molecular Recognition Features

MoRF SequenceStartStop
NANANA