<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21327

Description Uncharacterized protein
SequenceMDRRDAPASMSSSSSAPAAPLDGDKKRGPQWNAGHPDQLSADDGQMMPVSYALRPPPWRPRLHPGSTAIGVPDLFRPGEGRPEDDMSETTVRNGLSLKPVVANETFSAHDMIYDRLKATGLVTNLATLFDEVVTRRFELNMARKGLVSDHQFKQPPRVTLNDVKLNAYIKELADPDVPLKKLARSVPHGYRGERMLEMLWTGAATGAALKGTSAVAAAAAAAAAAAAAAASSSSSSSAEASDAGRKCVDIDRAVWFIRVVGASEIASSKARQTNVANYTAEWTSVVTGWLKRQISELTAAVTTSSPSSSPATAGRLAAAMTPTGLRGSGPKEPTGSLLLDTETSKRWVSKWTYSLNLVRALAMQRILDRRALIRWAIDQLRAAHPWQAPFVLVLVQENFEYASSDVQLLHLLIDTVCHKLAEYSKSQVMPSPTMVILELKRLLVVAFDANPEAFINPARWVRHASTILATIREAKVSEEQRLPLVEERNMKLVAPKAAGMKTRSKELEEYEDIHLLDSFQADDDAIQLFTDLSLLQSGTIRTLRDKVATLLTWATTTRRCGVHRPILAARLLQLLEERWSKGKSRGRRSTNDKLDLDTMLIDWVSSVDAAMEGPTSILTSIDLASLVTLVGELIRRRCFSFPRYIQRLTARGLTASTSSSKAVKNNARESLLVKLLRSVAVEDCPASLQHQRRTAIYGNRTKESYEEAMERRATRELLAELSWLQQPRSNGVIGEHQAEGDGDLNAPSGVPHFWASSRYVKNRLVARLVMGPIRAHGPEALFTTPRRLEQLAQLLGDAEEFADLYEILDRCLQSDDKSLIAPVCAVMLRHSLIWASLGDPSPLLRRIAALVTEGAMSGLQMIVAVRTLSVFGLLQPMGTQRANDPTKPDAAALERLRTAIRSIQASQDTVAPDVVAAEISSGALNAELVLRELCVRRDVSDEGSFTTAQGDASLIAWLVEVVASSLQSATLEEWDDAAKRVFQDERESPSRFVKFAVELVGRGILSPRIFLLDVLAPVASDCAQGKLDDGAKEALLKSTTLLIDAQSSTLSPLQGASLPVLLRRDCRAAFCTLLINLCIVGSGSGSPGETALCDVICRKPEVRAALYPHLLDIVGTIKSICVATWRAGVNVDTEATLSHILSLLVDDEWNAGLAAPQISHPVELDPAYILDRLQPFSFSQTLAELAGVVLERLERAEGGLQARAQSKLQALAKCTFDRLFSGRAGLELGIHLLRESSARSFAGMVLEEALSRLLARTSDAESTLGDKNADADSLYALLTLSHEQHTVTTASGTANSAALLRILIEQLESAATDAEANAIPTASTHLLVRLVNLLLLVDNLWSAASRPQAPRLFASLVKLCVSVDLHSFDVNLSQDVDGEDADEDIIAPLLDTATNLLVQVPTDVAASCLHLAKASLPRQEGDDDETLLSFVDPPLSNEVLRRLTWLFGSFSIASTLSAPLSNATASGQSAGGTRASSNSVSGGSLQTSTAGNATMIDVQASSASAAFVNGHFLTVEERPWDWHDNVEFAQAISGTTHVTAAATSKQGSAEGDEGYGGEAGMESVPLLNSASISLARFGAVKTRDRVPTLCVEEGGRGSNGLAPPPQLDSELDYGERFGGEPLYARDARRGIVEQGVVGLAFGGGVDPTVFEDQDEELDVVKDEDASKAGPKRKRSSTGIHPHSFMYF
Length1687
PositionKinase
OrganismAcaromyces ingoldii
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Exobasidiomycetes> Exobasidiales> Cryptobasidiaceae> Acaromyces.
Aromaticity0.05
Grand average of hydropathy-0.107
Instability index43.17
Isoelectric point5.59
Molecular weight182076.47
Publications
PubMed=29771364

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21327
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     165.20|      53|      69|     215|     283|       1
---------------------------------------------------------------------------
  228-  283 (78.72/78.62)	AAASSSSSSSAEASdAGRKCVDIDRAVwfIRVVGASEIASSKARQTNVAN.YTAEWT
  299-  352 (86.48/50.84)	AAVTTSSPSSSPAT.AGRLAAAMTPTG..LRGSGPKEPTGSLLLDTETSKrWVSKWT
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     133.03|      37|     521|     939|     975|       2
---------------------------------------------------------------------------
  779-  814 (26.35/13.24)	...EALF.TTPRrleqlaqllGDAEEFADLYEILDRCLQS................
  939-  975 (68.23/48.45)	VSDEGSF.TTAQ.........GDASLIAWLVEVVASSLQSA.......TLEE..WD
 1480- 1521 (38.45/23.42)	VSG.GSLqTSTA.........GNATMI....DVQASSASAAfvnghflTVEErpWD
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     141.51|      44|      45|     629|     672|       3
---------------------------------------------------------------------------
  629-  672 (70.09/44.19)	LVGELIRRRCFSFPRYIQRLTARGLTASTSSSKAVKNNARESLL
  675-  718 (71.42/45.17)	LLRSVAVEDCPASLQHQRRTAIYGNRTKESYEEAMERRATRELL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.41|      23|      45|    1365|    1389|       4
---------------------------------------------------------------------------
 1365- 1389 (32.11/23.89)	LHSFDVNLSQDvDGEDaDEDIIA....PL
 1409- 1435 (34.31/17.17)	LHLAKASLPRQ.EGDD.DETLLSfvdpPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.15|      16|      24|    1186|    1201|       5
---------------------------------------------------------------------------
 1186- 1201 (27.01/14.16)	AGVVLERLERAEGGLQ
 1212- 1227 (27.14/14.26)	AKCTFDRLFSGRAGLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.32|      24|      32|    1040|    1067|       6
---------------------------------------------------------------------------
 1040- 1067 (36.95/32.76)	TLLID...AQSSTLSPLQGASLPVLlrrdCR
 1072- 1098 (39.37/24.09)	TLLINlciVGSGSGSPGETALCDVI....CR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      81.77|      21|      46|    1249|    1269|       9
---------------------------------------------------------------------------
 1249- 1269 (31.96/19.32)	ALSRLLARTSDAESTLGDKNA
 1273- 1291 (22.24/10.85)	SLYALLT.LSHEQHTVTTAS.
 1298- 1318 (27.57/15.49)	ALLRILIEQLESAATDAEANA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.14|      19|      45|     526|     546|      10
---------------------------------------------------------------------------
  510-  528 (32.11/23.09)	YEDIHLLDS..FQADDDAIQ.L
  529-  550 (21.03/20.72)	FTDLSLLQSgtIRTLRDKVAtL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.76|      21|      39|    1576|    1597|      13
---------------------------------------------------------------------------
 1576- 1597 (33.52/28.44)	RFGA..VKTRDRVPTLcVEEGGRG
 1616- 1638 (33.24/21.42)	RFGGepLYARDARRGI.VEQGVVG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21327 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MDRRDAPASMSSSSSAPAAPLDGDKKRGPQWNAGHPDQLSADDGQMMPVSYALRPPPWRPRLHPGSTAIGVPDLFRPGEGRPEDDMSETTVRNGLSLKP
1
99










Molecular Recognition Features






MoRF SequenceStartStop




1) TGIHPHS
1677
1683