<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21316

Description Uncharacterized protein
SequenceMTSNFWQSSQCNHWLLSRRQLAIARSEDLQYARNAEELAALRIWFTNCICSLTKRLSLRQRITATAIVFFNRFYSCSPANSLSSTDPALVATACVYVASKVEETPVHIRNIVSEATKMWNSLGYFAFPAEVTDVAEMEFYLLEDLQFHLVVHHPYKSLITIATAAGKGRSMVDFEKKRLSSKGAGGAAAAAQAGGVGLGLSTPLPISLDSSSLGPSSDASNLFDADLAYGTPGTSANGATKAADMDKVAQMRALEQTIEERNRMMLHQGDDGMPIARLEELDEQALQMAWFLLNDTYRTDVILLYPPHLIAIASIFLALVLHDSSRTKMLSSKRWMDSRRSRYEAMVRGQGPSELLTKPPVPASTPTASASEGASASSTMPGKTASTPRPGAGNSATSPSASSGATPSNAPLRPHANSNPWRSSAQRPGNSSSQAQTATTPSTAASPATASTPYDTPRQALDASPAPSPIDQASPATAPPLPPHAAAAAQQPPPPKEQAPLPPPPAPPPDAMTFLATLNVDLSLVGEVVQEMLSLYALWHRIGAEAGAGAGAGASSSGGAEQDDIGPIDIADGSAMLKRLNRMRERRFQDLAQTRPSAS
Length599
PositionKinase
OrganismAcaromyces ingoldii
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Exobasidiomycetes> Exobasidiales> Cryptobasidiaceae> Acaromyces.
Aromaticity0.06
Grand average of hydropathy-0.259
Instability index59.18
Isoelectric point6.44
Molecular weight63574.91
Publications
PubMed=29771364

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP21316
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     124.08|      24|      24|     463|     486|       1
---------------------------------------------------------------------------
  386-  417 (30.48/ 8.45)	STPrpgagnsatSPSASSGATPSNA.PLRPHAN
  463-  486 (49.30/17.69)	ASP.........APSPIDQASPATAPPLPPHAA
  489-  511 (44.30/15.23)	AQQ.........PPPPKEQA.PLPPPPAPPPDA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.57|      20|      26|      50|      69|       2
---------------------------------------------------------------------------
   50-   69 (34.12/25.12)	CSLTKRLSLRQR.ITATAIVF
   76-   96 (32.45/23.49)	CSPANSLSSTDPaLVATACVY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.16|      21|      26|     179|     203|       3
---------------------------------------------------------------------------
  183-  203 (34.91/16.86)	GAGGAAAAAQAGGVGLGLSTP
  212-  232 (32.25/10.64)	SLGPSSDASNLFDADLAYGTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.55|      19|     245|      21|      45|       4
---------------------------------------------------------------------------
   21-   45 (26.61/31.52)	LAIARSEDLqyarnaEELAALRIWF
  273-  291 (35.94/24.26)	MPIARLEEL......DEQALQMAWF
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP21316 with CycC domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) GAGAGAGASSSGGAEQDDIGPIDIADGSAM
2) RRSRYEAMVRGQGPSELLTKPPVPASTPTASASEGASASSTMPGKTASTPRPGAGNSATSPSASSGATPSNAPLRPHANSNPWRSSAQRPGNSSSQAQTATTPSTAASPATASTPYDTPRQALDASPAPSPIDQASPATAPPLPPHAAAAAQQPPPPKEQAPLPPPPAPPPDAMTFLAT
547
339
576
517

Molecular Recognition Features

MoRF SequenceStartStop
NANANA