<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21315

Description Uncharacterized protein
SequenceMGTQKGKKREQDDARGSSLSNDSSRSADEADGPPAAAGGPNDERRHDDKKHKQKKRRGANACVICRRLKMRCVPLEPELADRDNPGPPCQRCARLGHECRFDSLPRGMRAQQARLLLLQQHLQREASAPPPGSSVNVAEGKDKEGMMLLAKLEEARRQLEAHNARQQASRAPAGSEAEVALQQQQQQQQQQQQQQQKPWLATTGATQGNQTSPVSSNSGGSAWTATDTPWIEHDGVHWPFASSSLTTSVTGASQELPFQTVIPGAGAGSGSSTSSGPQSRRESRQREKKRRKLGPLLPSDSLMDPLGMLAEASLGNDGDEAKIGGDEDEEKGGKGLVNATTPVAAAAAAANAGQEVTSERYFRRKNKAAPFRRGNEECHGHRLLESGLLLWADVCTFFDVFFDRCAQHFLLLDANFHTPDLVASRSAFLLAAICTVASRYVGDERRAGLNGECFDEATRLAAQCLTKGTKSVEIVQGLLLLSMWMPASKHWEDDRAWVYSGLAMRIATDLGLSYHQGAFDDMPYDVRLEVVNRQRTWLCCYAVDKSFSALMGKPDMLHDDDLIVHCRWWCLSASDGREDERLARPWHAAIAAFVDLLRTLCRQLKHLRSWNLSRPTTTTTMTMMAKTTTTTKAGSTHEDDGHDAKMVSINIFNEELDEWNSFWNSRKLFTLPERCKTAELDRDSKLLLSLHQQWPLRLSYARLIVNSFGLQHCLNRQKRRGKEGVDVGLFFAVCWRSARGVILAAKDGMRGSLRWGADTQLVMVTYASVFLLKLVRSQAKLAEYHNKAEAIALVRDAADLLGSLAAGKTHTATLYASFLRSLLDAQPQADTDATQEQQQQQQQQPTPTQPHTAPTIPTTADSFDMPLNGPDTFNFLAAQSQDDPAISAEWISSLEDLPAFHNTLMNLPEDGILNDSFWSELLPSYGYSQPHPYDAAPSALQPVNLPFQHSST
Length952
PositionTail
OrganismAcaromyces ingoldii
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Exobasidiomycetes> Exobasidiales> Cryptobasidiaceae> Acaromyces.
Aromaticity0.07
Grand average of hydropathy-0.549
Instability index54.04
Isoelectric point6.55
Molecular weight105171.94
Publications
PubMed=29771364

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW
DNA-binding transcription factor activity, RNA polymerase II-specific	GO:0000981	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21315
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     176.31|      37|      45|     102|     138|       1
---------------------------------------------------------------------------
    5-   47 (30.24/12.41)	.............KG......KKREQddARGSSLSNDS.SRsadEADGPPaaaggPNDERRHD
   53-   96 (50.34/25.70)	QKKR.........RGanacviCRRLK..MRCVPLEPELaDR...DNPGPP.....CQRCARLG
  102-  138 (61.03/32.77)	DSLP.........RG......MRAQQ..ARLLLLQQHL.QR...EASAPP.....PGSSVNVA
  144-  180 (34.71/15.37)	EGMMllakleearRQ......LEAHN..AR..........Q...QASRAP.....AGSEAEVA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     130.55|      26|      45|     203|     229|       2
---------------------------------------------------------------------------
  183-  204 (29.20/10.41)	..QQQQQQQQQQQQQ.QKPWLAT.......................tG
  205-  251 (31.42/12.88)	ATQGNQTSPVSSNSG.GSAWTATDTPwiehdgvhwpfassslttsvtG
  252-  277 (28.42/ 9.73)	ASQELPFQTVIPGAGaGSGSSTSSGP......................
  833-  857 (41.52/17.23)	ATQEQQQQQQQQPTP.TQPHTAPTIP......................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.17|      31|      78|     338|     378|       3
---------------------------------------------------------------------------
  338-  378 (41.89/48.00)	NATTP..VAA......AAAAANAGQEVTSERyfrrknKAApfrrGNEEC
  415-  453 (47.28/27.63)	NFHTPdlVASrsafllAAICTVASRYVGDER......RAG....LNGEC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.56|      32|      51|     745|     780|       4
---------------------------------------------------------------------------
  745-  780 (39.67/42.76)	AKDgMRGSLRWGaDTQLVMVtYASvFLLKLVRSQAK
  797-  828 (54.89/35.46)	AAD.LLGSLAAG.KTHTATL.YAS.FLRSLLDAQPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.93|      14|      88|     478|     497|       6
---------------------------------------------------------------------------
  483-  497 (27.16/26.40)	MWMPASKHwEDD.....RAW
  551-  569 (24.77/ 7.29)	MGKPDMLH.DDDlivhcRWW
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21315 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MGTQKGKKREQDDARGSSLSNDSSRSADEADGPPAAAGGPNDERRHDDKKHKQKKRRGAN
2) QPQADTDATQEQQQQQQQQPTPTQPHTAPTIPTTADSFD
3) RAQQARLLLLQQHLQREASAPPPGSSVNVAEGKDKEGMMLLAKLEEARRQLEAHNARQQASRAPAGSEAEVALQQQQQQQQQQQQQQQKPWLATTGATQGNQTSPVSSNSGGSAWTATDTPWIEHDGVHWPFASSSLTTSVTGASQELPFQTVIPGAGAGSGSSTSSGPQSRRESRQREKKRRKLGPLLPSDSL
1
826
109
60
864
302










Molecular Recognition Features






MoRF SequenceStartStop




1) NACVI
2) RHDDKKHKQ
3) RLLLL
60
45
114
64
53
118