<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21302
Description |
Mediator of RNA polymerase II transcription subunit 4 |
Sequence | MASHQVDLDQIALKRVLLDLLDHHAELSHALLTSSTAVVDTPESIRPLLSSVSASDYAEGEKVGARAGPSTEKDSQVQDTLAQLQQADRALRSLLPFISLHRAAHDSLAQQTERVHLLSSQFSKAFGDVNDLNTELGDLVRNAKAQVKSSTRATKRPLNVEHLLSLASVVGYQTSKPWGSVGSATGRKKAKVNKAEASADDRMAEDRAPGVNGEEAPTVAHTNHEPRTLSRSPTPAPQHPSQLEQHLPYPSQNILRSGSLGSDPPSWNEFRRQRRLEMREVGQEAERTAPEEHVQDANGQQEEVLTWTATQRERGRADEDAFSLDL |
Length | 326 |
Position | Middle |
Organism | Ceraceosorus guamensis |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina>
Exobasidiomycetes> Ceraceosorales> Ceraceosoraceae> Ceraceosorus.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.702 |
Instability index | 44.95 |
Isoelectric point | 5.82 |
Molecular weight | 35735.05 |
Publications | PubMed=29771364
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364141
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP21302
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 298.02| 98| 112| 26| 136| 1
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29- 136 (143.34/99.92) HALLTSSTAVVDTPESIRPLLSSVSASDYAEGEK...VGARAGpstEKDSQVQDtlAQLQQADRALRSLLPFISLHRA...AHDSLAQQTervhlLSSQFSKAFGDVNDLNTEL
144- 247 (154.68/80.74) KAQVKSSTRATKRPLNVEHLLSLASVVGYQTSKPwgsVGSATG...RKKAKVNK..AEASADDRMAEDRAPGVNGEEAptvAHTNHEPRT.....LSRSPTPAPQHPSQLEQHL
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