<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21286

Description Uncharacterized protein
SequenceMSGSFGPSPVASGSQKHETKNAIQGATKPIVYELIPPKWRPRLHPGSRAIGAPDIYIRRPKEPGPPEDEMSEVNVRNGLNARPAVGNETFSAHDMIYDRLKGKQVVNQLGSLFEEVAQRRKQLAGLRCGPTASQYRQPQRVTLNEVKLAAYVKDLADPSVPIGKLARSVPHGYRGERMLDMLWNGGSVSGAMAAMKSQPSIGSSSSNGVNASTPGGERNGLPNSVEISRAVWFIRVVGASEISSSRLRQGNSAFYTSEWTATMMGWLRRQIVELIITHHHSSVSDSPAAPPSPMPSRNRSSISTPQHNEEPYALILEDDFRDRWMAKWNYSVALLRALANEGLIDCQVAARFSIDMFRTANVAQIFITLALFQEFLDIIANSITLSHLALTVLTSKLKDLEEQVTSSSTFIQKEITAMLLYVFNTRPDSFVSPSCWQDLSRIINEARKSGASDCKLKSIAERNEKLLASFTNFTSADDEQSTDLARLQDLMILDRIPAHEDLQSTFELYFGRYCASISDRIRTLLVWATCDWRVGTHRPFAVATMLNMYIRYQPSRSQKRATHKSKDGKRMVLDRIDLDAIVMSWITDVDLAKKQNVGEEESEGNQKSLRWQNVLFSTSLHEMIILIGELYRLGCFSFPKYLQRLTARGLTAMGGREIRPDSEGTNGKHQEIPVADSLHSKLLRSVPLIACPAPLEHQRRVAIYGNRAKESWEEAMERRALRELSSALPWLSGSQDASEAQGKSEHFDLQRKLPRFWGSSRYIRSRIVQLHLLPSFREYVYGQEVLQDYQLSQFASLLIEAQEFAALQEVLEDISQHPQTYSETIIKVANSYAKQNRLVLLCMGSVFRTDYESGINAEKADPQQGEGNSAAKELGVPRDEDDLSTFSSSLRTFSEGRLPESMEMMKNHYASPRSLLSVANEYLSAGQEGNIKLISNWFRSLLLAYKGESQRWVQDLSNCLQDTSLSNNDVDILVNLSIVQISSQPSSFSDIVRNFCLPTLITYAGGSEANDTASLRAVVGILSSVFIPSDGLKRSWVVLDINFRSTDSHWTLSADILRMISALRKAENVNQQSSLLNDLEILRTSICRDENVRCLLQMNLKDSIDLVRSTVPAGDFHTVMRDLLPARWPWTSDDELITGMSRIFENADQWRWSQMLCENAITIEAIRSKTKEGSISSNKLNELARLFSERVLSSVDAACSSISITGLFGSLSSSNGAVFCIGLVDERLRVLNKQLEATFTDERLLQSELESLLRLWQKMAPMTISASALSAQAFRFVTEWLESNLPASPVQEVVSDQQNSDITTSEADLPNGELAVRLGILCFLMKLDNILMLPITKAFAPRLFCAIIQIALSLSRRPGMSERKVETLLDVARYLLQQAPLELQQTMRQRASEQIETGLLTHPSPLDRVTETIGRLVNIDADALGSNLTSNIGGKKISLIEAQSSSSAISDGQFAAVQIKPWDLHPNVEALVQGKSVATADAGQGSAHPIASFTEMNSLNNNGPISLQHFRAYRTLDRLPERSSLPLRKRTALDNSSLKVPFILPSEQNYGMNLAGQPIYARDAKRGLLVTSSNTAKMGLSAHDLQQLVPALCPPPKHDHEDTAIDKQGKDASNGAKKSNTANEKSPVKPSIAKGKADKKETANGKSTDSKTAGGNANSTARKRKTSNASVQDQKAAKATTTAASRKRTKK
Length1691
PositionKinase
OrganismMeira miltonrushii
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Exobasidiomycetes> Exobasidiales> Brachybasidiaceae> Meira.
Aromaticity0.06
Grand average of hydropathy-0.339
Instability index51.00
Isoelectric point8.51
Molecular weight187488.67
Publications
PubMed=29771364

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21286
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      94.19|      20|      23|    1633|    1653|       1
---------------------------------------------------------------------------
 1612- 1630 (31.48/16.69)	ASNGAKKSNTANEKS.PVKP
 1633- 1652 (32.33/17.48)	AKGKADKKETANGKSTDSKT
 1657- 1676 (30.38/16.58)	ANSTARKRKTSNASVQDQKA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.98|      23|      23|     766|     788|       2
---------------------------------------------------------------------------
  766-  788 (41.47/25.61)	RIVQL.HLLPSFREYVYGQEVLQD
  790-  813 (31.51/17.76)	QLSQFaSLLIEAQEFAALQEVLED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.18|      21|      23|     714|     734|       3
---------------------------------------------------------------------------
  714-  734 (36.03/21.39)	EAMERRALRELSSALPWLSGS
  739-  759 (39.15/23.92)	EAQGKSEHFDLQRKLPRFWGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.36|      12|      21|    1186|    1199|       5
---------------------------------------------------------------------------
 1186- 1199 (16.25/14.64)	LFSErvLSSVDAA..C
 1207- 1220 (20.11/10.54)	LFGS..LSSSNGAvfC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.23|      17|      20|    1410|    1428|       6
---------------------------------------------------------------------------
 1410- 1426 (27.84/21.51)	TETIG..RLVNIDADALGS
 1429- 1447 (22.39/ 8.49)	TSNIGgkKISLIEAQSSSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.64|      22|      22|    1065|    1086|       8
---------------------------------------------------------------------------
 1065- 1086 (34.13/24.04)	KAENVN..QQSSLLNDLEILRTSI
 1088- 1111 (30.50/20.61)	RDENVRclLQMNLKDSIDLVRSTV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      99.07|      23|      23|     914|     936|       9
---------------------------------------------------------------------------
  884-  907 (32.18/20.90)	STFSSSLRTFSEGRlPESMEMMKN
  914-  936 (35.77/24.23)	SLLSVANEYLSAGQ.EGNIKLISN
  940-  958 (31.12/19.91)	SLL.LA..YKGESQ.RW.VQDLSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.30|      14|      16|     439|     452|      10
---------------------------------------------------------------------------
  439-  452 (22.08/13.20)	LSRIINEARKSGAS
  456-  469 (21.22/12.39)	LKSIAERNEKLLAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.95|      17|      17|    1483|    1499|      11
---------------------------------------------------------------------------
 1483- 1499 (28.91/19.01)	GQGSAHPIASFTEMNSL
 1503- 1519 (29.05/19.14)	GPISLQHFRAYRTLDRL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21286 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GLSAHDLQQLVPALCPPPKHDHEDTAIDKQGKDASNGAKKSNTANEKSPVKPSIAKGKADKKETANGKSTDSKTAGGNANSTARKRKTSNASVQDQKAAKATTTAASRKRTKK
2) IGAPDIYIRRPKEPGPPEDEMSEVNVRNGLNARPAV
1579
50
1691
85










Molecular Recognition Features






MoRF SequenceStartStop




1) IAKGKADKKETANG
2) IQGATKPIVYELIPPKWRPRLHPGSRAIGAPDIYIRRPKE
3) TARKRKTSNASVQDQKAAKATTTAASRKRTKK
1632
23
1660
1645
62
1691