<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21284

Description Kinase-like protein
SequenceMEAYRAFRDKVRQPVLSTYNILGFLSSGTYGRVYKASLKNLPAGYRHPSGQHSNSSMNDDETSGLVFAIKKFKPDKEDHATYTGISQSAMREIALNRELQHENIVQLREVILEDKAIYMVFHYASHDLLQLIHHHSTALRTQISLPVLKSLLFQLLNGVHYLHCHFVLHRDLKPANILLTCDGVVKIADLGLARVYHAPLQSLYSGDKVVVTIWYRAPELLLGARHYNSKIDMWAIGCIWGELLALRPMFKGEEAKMDPKTKTTPFQSDQISRIVEIMGMPNKERWPDIEFMPDHKHIWSKLRMENFPNILYSWYEQRANSSSGFDLFDALLQYDPNKRISAKDALMHPWFQENDPLPTMNAFASLPNGNTIYPARRLIKDESDPKMVITQLPAQGSGSNTLTAQAGGGTIHYGAGTNTGAGATAGGGGGGVQGMMGSGGNGSNSLASIAAAAANSMAGGGQAHSALGQQPLSASAFLSAVGPPAPPPAPGSAGSVGPPSSLNSVGPSSSIGQATNHSSAANSNAPSNSRNIGGGAGGGSNLVATATANAANAANRQAKRTKHR
Length564
PositionKinase
OrganismMeira miltonrushii
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Exobasidiomycetes> Exobasidiales> Brachybasidiaceae> Meira.
Aromaticity0.07
Grand average of hydropathy-0.305
Instability index48.39
Isoelectric point9.21
Molecular weight60597.85
Publications
PubMed=29771364

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21284
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     116.60|      28|      29|     409|     437|       1
---------------------------------------------------------------------------
  411-  437 (46.07/17.92)	..IHYGAGTNT.....GAGATAGGGGGGVQGMMG
  439-  468 (37.29/13.44)	G....GNGSNSlasiaAAAANSMAGGGQAHSALG
  475-  502 (33.25/14.28)	SaFLSAVGPPA.....PPPAPGSAGSVGPPSSL.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.03|      23|      24|     508|     531|       2
---------------------------------------------------------------------------
  508-  530 (38.71/22.78)	SSSIGQ...ATNHSSAANSNAPSNSR
  535-  560 (32.32/13.45)	GAGGGSnlvATATANAANAANRQAKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.97|      12|      22|     174|     185|       5
---------------------------------------------------------------------------
  174-  185 (21.82/12.45)	PANILLTCDGVV
  199-  210 (21.15/11.88)	PLQSLYSGDKVV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.39|      21|      34|     310|     331|       6
---------------------------------------------------------------------------
  310-  331 (32.47/25.93)	ILYSWYeQRANSSSGFDLFDAL
  346-  366 (39.92/27.17)	LMHPWF.QENDPLPTMNAFASL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21284 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AGGGQAHSALGQQPLSASAFLSAVGPPAPPPAPGSAGSVGPPSSLNSVGPSSSIGQATNHSSAANSNAPSNSRNIGGGAGGGSNLVATATANAANAANRQAKRTKHR
2) DPKMVITQLPAQGSGSNTLTAQAGGGTIHYGAGTNTGAGATAGGGGGGVQGMMGSGGNGSNSLASIAA
458
384
564
451










Molecular Recognition Features






MoRF SequenceStartStop




1) NLVATATANAANAANRQAKRTKHR
541
564