<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21283
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MDQTTIPIRPSRSDRLTTYFRNPEYLRAVGGQLTQYTVLDYFSKSDYYEQGCNNAVLQMQSAASLSAWERRNDPFTIEQELKRFTGLEYVLVHAKQPDLFVIHKRWRSSPTITNTLEAYYVLQGNITMAADILAILGNKFVSTVSSLQQSLEIARNAQPDFNPREGYAWRIAAEAQPEDTTEGEDEQSVDTHPNQSQREEVMAQVASQVETAS |
Length | 213 |
Position | Head |
Organism | Meira miltonrushii |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina>
Exobasidiomycetes> Exobasidiales> Brachybasidiaceae> Meira.
|
Aromaticity | 0.09 |
Grand average of hydropathy | -0.583 |
Instability index | 63.62 |
Isoelectric point | 4.87 |
Molecular weight | 24221.57 |
Publications | PubMed=29771364
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364143
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP21283
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 44.54| 13| 15| 153| 166| 1
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153- 166 (21.02/16.43) IARNAQPDfNPREG
171- 183 (23.52/13.01) IAAEAQPE.DTTEG
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 68.61| 20| 33| 69| 88| 3
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69- 88 (33.84/21.00) ERRNDPFTIEQELKRFTGLE
104- 123 (34.77/21.74) KRWRSSPTITNTLEAYYVLQ
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