<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21277

Description Mediator of RNA polymerase II transcription subunit 17
SequenceMDGKMEISLDKLPIKRLDVIEENGLERFPPDVGYEEKRQSLIRRIDFAWAVEKDENKKQKKSSKESAATQWQWQSMVENLQLAHQELSVIIDLINTVETNDAVTVASMTRPKPFHDEVMSDLAVSAATKLQCFRHLGKYFKQSAKALERQVAREARFYGALIRLQQNWKVKRQRVAASASGNEGFTIDLFDNSLYDPAAIFRPSSLSTVRVDHDSAGMLAINLPPNSYRSLQFGFLGCDPGVSPIESSQTKIRLSSEAEKESVFDLVNREAFNQSLGVNVTGIQENYLQLNIGQGTSVFISLVPSRGEQIVESPSTQNLENTILPLDTLDGLELAEDKPDTVKKTSVIPDQISCEIYLQQIFHQHVFVKAKDRPTSAGARVPGQLAKEGPGLLGHFCMSLAHRIFSNKVLKALENVVKGVPYLQLLSHPTWHSRTSSWMLFVKIPESILHACQTRTSDMHHMRNITKSQFHTKVVVTDDCINVEGEGAPNVVGLFKGNSEEICLMNRYDCDLADLPVIILQQVASQVIRWLHEEALMVGIKANRDFLCLSFELDQGETLSLVAHVDPEDGEGCISWWLVMMVVL
Length584
PositionHead
OrganismPrunus yedoensis var. nudiflora
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Rosaceae> Amygdaloideae> Amygdaleae> Prunus.
Aromaticity0.07
Grand average of hydropathy-0.222
Instability index45.72
Isoelectric point5.72
Molecular weight65472.05
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21277
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     171.18|      52|     317|     181|     233|       1
---------------------------------------------------------------------------
  181-  233 (87.38/67.33)	GN..EGFTIDLFDNSLYD.PAAIFRPSSLSTVRVDHDSAGMLAINlPPNSYRSLQF
  497-  551 (83.80/59.73)	GNseEICLMNRYDCDLADlPVIILQQVASQVIRWLHEEALMVGIK.ANRDFLCLSF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.89|      25|     317|      12|      42|       2
---------------------------------------------------------------------------
   12-   42 (33.47/38.30)	LPIKRLDVIEengLERFPPDVgyeEKRQSLI
  324-  348 (42.42/27.28)	LPLDTLDGLE...LAEDKPDT...VKKTSVI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.08|      33|     221|     129|     161|       4
---------------------------------------------------------------------------
  129-  161 (57.58/40.73)	KLQCFRHLGKYFKQS..AKALERQVAREARFYGAL
  351-  385 (54.50/38.18)	QISCEIYLQQIFHQHvfVKAKDRPTSAGARVPGQL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21277 with Med17 domain of Kingdom Viridiplantae
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