<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21262

Description Mediator of RNA polymerase II transcription subunit 33B
SequenceMDFEPEFPKTTNTRYKCAACYKQYKKKEHLVEHINVSFHSVHQPRCGVCKKHFKSFESQREHVTGPLAKENCKRVFSEQGCDLCLKIFDSPNSLSAHKFMCRLSAPVPLVTMMERCEEFKHDINSSNEYHVGDGTEAIALDCEMVAGGSDGSLDLCARVCLIDEDETILFHTYVQPQYPVVNYRYEVTGLTEELLRDGMPLQKVQDKVLQILYNGKTKLLVGHSLENDLDCLRINYPDYLLRDTANYHPLMKTNLVSHPLKYLTRTYLGYDIQSGFHDPYEDCVSAMRLYKRFCALDHQKEGNVASLAMLCAKDIPGSFDSWETDKLEKMTLHELYEMSRPNYKYFICVIRIPYRVRSFCPVVHVMRCLKVKRVSYSPSPLRTRTATRSSGRFRLSSSLNSAAVALPSVELAHLLVSHICWANHVPITWKFLEKALTVKIVPPMLVLALLSTKVVPNRQLHPAAYRLYMELLKRHTFLFASQLNGPNCQKIIKSIDDVLHLSQLYGLQVCEPGVVIVEFVFSIICELLDASLDDEGLLELTPDKKSRWSTRPEDMEIDGHDCFNEKRSEQNEGLQKVNTAMAIEIIVELLQNKVTSRILCLTRRNLPSHWGGFIQKIQVLAANSSVLRTLKHITPESLLQLTSDTRRLLTRECKIIARKEFHAVLSSGSLRSSASQSHGVSSSAFWLPIDLFLEDAMDGSEVAIISAVETLTGLVKALQAVNGTTWHNTFLGLWIAALRLVQRERDPREGPVPRLDTCLCMLLSITTLAVTNIIEEEEAELMEEIEGDRTNQRKEQAPGKRRKAKAIMSRSGLTVSNGYYESVSVNDMPINCMGNLRHLIVEACIARNLLDTSAYFWPGYVSARSSQVLRNVPGQVPGWSSIMKGSPLTPSLVNALVATPASSLAEIEKIYEIAVNGSDEEKISAVTILCGASLIRGWNIQEHICLFIINLLSPPVPADYSGSDSHLISYASFFNVLLVGVSSVDTVQIFSLLGLVPLLAAALMPICEVFGSSIPNISWTPTTGEELSCHTVFSNAFTLLLRLWRFDHPPLEHMMGDSPTVGNQAGPEYLLVLRNSRLASFGNSPMDRIKSRRVSKFITFPSKTITMDCFPKLRLWFQQHQKCICSTLSGLVPGTPIHQIVDALLTMMFRKINRSSQPLTPVTSGSSNSSASGTDESSIRLKVPAWDILEATPFVLDAALTACAHGRLSPRELATGLKELADYLPATLATIVSYFSAEVTRGIWKPACMNGTDWPSPAANLSLVEQQIKKILAATGVDVPSLAVGGSAPAMLPLPFAALVSLTITYKLDRASERALTLIGQP
Length1322
PositionTail
OrganismPrunus yedoensis var. nudiflora
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Rosaceae> Amygdaloideae> Amygdaleae> Prunus.
Aromaticity0.07
Grand average of hydropathy-0.033
Instability index46.96
Isoelectric point7.34
Molecular weight147259.63
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
3'-5' exonuclease activity	GO:0008408	IEA:InterPro
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro
rRNA processing	GO:0006364	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21262
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     192.56|      61|      71|      45|     110|       1
---------------------------------------------------------------------------
   45-  110 (101.28/67.12)	RCGVCKKHFKSfeSQREHV.TGPLA.KENCKRVF..SEQGCDLCLKI..FDSPNSLSAHKFmcrLSAPVPLV
  115-  181 (91.28/48.31)	RCEEFKHDINS..SNEYHVgDGTEAiALDCEMVAggSDGSLDLCARVclIDEDETILFHTY...VQPQYPVV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.03|      28|      72|     789|     816|       2
---------------------------------------------------------------------------
  789-  816 (47.45/31.66)	RTNQRKEQAPGKRRKAKAIMSRSGLTVS
  864-  891 (51.59/35.11)	RSSQVLRNVPGQVPGWSSIMKGSPLTPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     176.27|      56|     356|     586|     702|       3
---------------------------------------------------------------------------
  629-  689 (84.88/160.79)	TLKHITPESLLQLTSDTrrLLTRECKIIAR.KEFHAVLSSGSLRSSASqshGVSSSAFWLPI
 1127- 1183 (91.38/40.76)	TLSGLVPGTPIHQIVDA..LLTMMFRKINRsSQPLTPVTSGSSNSSAS...GTDESSIRLKV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21262 with Med33 domain of Kingdom Viridiplantae
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