<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21243

Description Mediator of RNA polymerase II transcription subunit 25 isoform X2
SequenceMAEKQLIVAVEGTAAMGPYWSTVISDYLDKIIRCFCGNELSGQKPSTSTVELSLVTFYTHGSYCGCLVQRSGWTRDLDLFLQWLSAIPFSGGGFSDAAIAEGLSEALMFLRLHFKLTFTILLLCNSDVPYVQNGNQNQQNVDCQKHCILVAASNPHPLPTPVYRPQMQNLEQNESIDAQTENRLYDAEAVAKSFPQCSVSLSVICPKQLPKLRAIYNAGKRNPRAADPPIDNAKNPQFLVLISENFMEARATLSRPGSTNLPSNQSPVKMDIAPVASVTGTPPTSMPSVNGSVMNRQPVAVGNVPPATVKVEPSTVSSMVAGPAFPHIPSVRPPSQGVPSLQTSSPSSASQEMTTNNENVPDLKPVVSGVTHPSRPVGSILNNISQARVMNSAALTGGTSIGLQTMGQNPMAMHVSNMISSGMASSVGAAQNVFSSSGSGTLTQVAQNSGLSSFTSANSNVSGNNNLGISQPMSNLQGGVSMGQSVPGMSQGNLSGPQMVQSAIGMNPNMMSALGSSGSSSGTGTMIPTPGMPQQVQAGIQSLGANNSSAPNVPLSQQTSSALQSAQSKYVKVWEGNLSGQRQGQPVFITRLEGYRSASASETLAANWPPTMQIVRLISQDHMNNKQYVGRADFLVFRAMNQHGFLGQLQEKKLCAVIQLPSQTLLLSVSRQSLPLDWNAFSWGEIAILITADCDYLLLFFFKIKF
Length706
PositionUnknown
OrganismPrunus yedoensis var. nudiflora
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Rosaceae> Amygdaloideae> Amygdaleae> Prunus.
Aromaticity0.06
Grand average of hydropathy-0.115
Instability index46.40
Isoelectric point8.41
Molecular weight75094.51
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP21243
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.65|      20|      22|     262|     283|       1
---------------------------------------------------------------------------
  274-  297 (28.00/12.48)	PVAsVTGTPP...tsmPSVNGSV.MNRQ
  298-  324 (26.65/11.28)	PVA.VGNVPPatvkvePSTVSSMvAGPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     282.31|      80|      81|     418|     498|       2
---------------------------------------------------------------------------
  344-  442 (94.98/34.81)	.........SSPSSASQEMTTNNeNVPDLKPVvsgvthpsrpvgsilnnisqarvmnsAA.LTGGTSIGLQ..TMGQNPMAMHVSNMISS..GMASS.VGAAQNVFSSSGSGTL
  443-  526 (131.66/53.67)	TQVAQnSGLSSFTSANSNVSGNN.NLGISQPM..........................SN.LQGGVSMGQS..VPGMSQGNLSGPQMVQSaiGMNPNmMSALGSSGSSSGTGTM
  533-  582 (55.67/17.91)	PQQVQ.AGIQSLGANNSSAP....NVPLSQQT..........................SSaLQ...S.AQSkyVK.VWEGNLSGQR............................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     142.40|      37|      38|     129|     165|       3
---------------------------------------------------------------------------
  129-  165 (71.78/41.96)	P...YVQN.GNQNQQNVDCQKHCIL.....VAASNPH.PLPTPVYRP
  167-  206 (41.34/21.16)	.....MQN.LEQN.ESIDAQTENRLydaeaVAKSFPQcSVSLSVICP
  210-  239 (29.27/12.91)	PklrAIYNaGKRNPRAADPP....I.....DNAKNPQ.FL.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.76|      14|      38|     328|     341|       4
---------------------------------------------------------------------------
  328-  341 (26.22/13.91)	IPSVRPPSQGVPSL
  367-  380 (25.55/13.36)	VSGVTHPSRPVGSI
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP21243 with Med25 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) ATLSRPGSTNLPSNQSPVKMDIAPVASVTGTPPTSMPSVNGSVMNRQPVAVGNVPPATVKVEPSTVSSMVAGPAFPHIPSVRPPSQGVPSLQTSSPSSASQEMTTNNENVPDLKPVVSGVTHPSRPVGSILNN
2) QVAQNSGLSSFTSANSNVSGNNNLGISQPMSNLQGGVSMGQSVPGMSQGNLSGPQMVQSAIGMNPNMMSALGSSGSSSGTGTMIPTPGMPQQVQAGIQSLGANNSSAPNVPLSQQTSS
251
444
383
561

Molecular Recognition Features

MoRF SequenceStartStop
NANANA