<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21233

Description Mediator of RNA polymerase II transcription subunit 8 isoform X1
SequenceMAAMEGVVQNQPPQPQQQQPPQPMAVERLNDAVQQQLNLESVKTRAISLFKAISRILDDLNAYAYANTTPKWQDILSQYSMVNLELFNIVDEIKKVSKAFVVHPKNVNAENSSVLPVMLSSKLLPEMEVEDNAKREQLLHGLQSLPIGSQIEKLKARIDMIGAACESAEKVLADTRKAYCFGTRQGIPIVPTLDKAQAAKIQEQENLLRAAVNFGEGLRLPVDQRQNTTALPMHLVDVLTVGDGAQPFAETSGMYLKNTPVSSSNLTAQSPLMQVSGSQLMGRPAASPGGTSVSNFDNTTTSPLPYANSPRSSTNMMNTPSPQQQSQQQKQQQQQQQQQKLMQLPQHQQQQLLAQQQFRQSAMQGLGQNQLQQLHDLQQGQAQKFQSLHGQHQMQFSQPLGHQQFQGRQLPSGHVQHGIGQNQLNPGNQMSRHLGQFSGTANSALFNAAQTTPSQMIPNISATMPSQSLLPRMQFELSGNNPQRSHASQMLSDQMFNMGAANTGGMMPLQQQQQQQQQQQQQHGSQGAFGNIPPNAQNLQSNMVALQGTPQNHPNFGQQRQQNQQ
Length565
PositionHead
OrganismPrunus yedoensis var. nudiflora
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Rosaceae> Amygdaloideae> Amygdaleae> Prunus.
Aromaticity0.04
Grand average of hydropathy-0.691
Instability index61.79
Isoelectric point8.95
Molecular weight62322.35
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21233
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     260.16|      45|      45|     324|     368|       1
---------------------------------------------------------------------------
  323-  350 (42.00/ 8.09)	.......................Q...Q........QSQQQKQQQQQQQ..QQKLMQL.PQHQQQ
  351-  395 (68.48/17.76)	QLLAQQQF..RQ...SAMQ.GLGQ...N........QLQQLHDLQQ.GQ..AQKFQSLhGQHQMQ
  398-  443 (48.11/10.32)	QPLGHQQFqgRQlpsGHVQhGIG................QNQLNPGNQM..SRHLGQF.SGTANS
  444-  488 (39.96/ 7.35)	ALFNAAQT..TP...SQM..........ipnisatmPSQSLLPRMQFEL..SGNNPQ...RSHAS
  489-  537 (61.61/15.26)	QMLSDQMF..NM...GAAN.TGGMmplQ........QQQQQQQQQQQQHgsQGAFGNI.PPNAQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.87|      18|      31|     176|     197|       2
---------------------------------------------------------------------------
  176-  197 (28.84/25.86)	RKAYCFGTRQGIPIvptlDKAQ
  209-  226 (31.03/18.12)	RAAVNFGEGLRLPV....DQRQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.58|      30|      48|     242|     271|       3
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  242-  271 (55.90/31.85)	G.DGAQP.......FAET..SGMYLKNTPVSSSN.LTAQSP
  282-  322 (38.68/19.86)	GrPAASPggtsvsnFDNTttSPLPYANSPRSSTNmMNTPSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.00|      22|     540|       1|      22|       4
---------------------------------------------------------------------------
    1-   22 (43.89/16.45)	MAAMEGVVQNQPPQPQQQQPPQ
  543-  564 (43.11/16.03)	MVALQGTPQNHPNFGQQRQQNQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21233 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AETSGMYLKNTPVSSSNLTAQSPLMQVSGSQLMGRPAASPGGTSVSNFDNTTTSPLPYANSPRSSTNMMNTPSPQQQSQQQKQQQQQQQQQKLMQLPQHQQQQLLAQQQFRQSAMQGLGQNQLQQLHDLQQGQAQKFQSLHGQHQMQFSQPLGHQQFQGRQLPSGHVQHGIGQNQLNPGNQMSRHLGQFSGTANSALFNAAQTTPSQMIPNISATMPSQSLLPRMQFELSGNNPQRSHASQMLSDQMFNMGAANTGGMMPLQQQQQQQQQQQQQHGSQGAFGNIPPNAQNLQSNMVALQGTPQNHPNFGQQRQQNQQ
249
565










Molecular Recognition Features






MoRF SequenceStartStop




1) FGNIPP
529
534