<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21227

Description Mediator of RNA polymerase II transcription subunit 23 isoform X1
SequenceMDQNQRSSSSSASASRAYQFHPARAAIVNLFDLYLGRSSRQKPEDSVREPPNKSQKRVVALNRELPPRNEQFLLDFEQLQSQFPDQDQLRVVTESVLISLVVQCSNHAPRAEFLLFALRSLCTIGHINWDSFLPSLLSSVSAAEMSVGQGSQAMPAVSSQSGMLQSSNNIPHSSNFQSSNPASPLPAVHGIGSPGQSAIEPSCVTMSPVKSSDMPCNGQQATARVNSSIRDNAISSLRQLCCKIILTGLEFNLKPVTHADIFSHMLNWLVNWDQKQLGVDESDGVKSWRPGKALIEWLHSCLDVIWLLVDEDKCRVPFYELLRSGLQFMENIPDDEALFTLILEIHRRRDMMAMHMKMLDQHLHCPTFGTHRIFSQTTPSVSGEAVASLRYSPITYPSVLGEPLHGEDLATSIPKGSLDWERALRCIRHALCTTPSPDWWKRVLLVAPCYRSPSQGPTPGAVFTSEMICEGTIDRIVELLKLTNSDINCWQEWLVFSDIFFFLIKSGCVDFVDFVDKLVSRLTEGDQHILRTNHVTWLLAQIIRVELVMSALNADARKVETTRKILSFHKEDRSSDPNSPQSILLDFISSCQNLRIWSLNTTTREYLNNEQLQKGKQIDEWWRQASKGDRMVDYMNMDDRSIGMFWVVSYTMAQPACETVINWLSAAGVAESLPGTNLQSNERLMVMREVSPLPMSLLSGFSINLCLKLAYQMEESLFSGQVVPSIAMAETYTRLLLIAPHSLFRSHFSHLAQRNPSVLSKPGVTLLVLEILNYRLLPLYRYQGKSKALMYDVTKIISALKSKRGDHRVFRLAENLCMNLILSLRDFFLVKREGKGPTEFTETLNRITVVTLAIIIKTRGIADADHLLYLQTMLEQILATSEHTWSDETLRFFPPLLRDFLITRIDKRGLAIQAWQQAETTVINQCTQLLSPSADPTYVMTYISHSFPQHRKYLCAGAWILMQGHPENINSVNLARVLREFSPRK
Length985
PositionTail
OrganismPrunus yedoensis var. nudiflora
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Rosaceae> Amygdaloideae> Amygdaleae> Prunus.
Aromaticity0.08
Grand average of hydropathy-0.143
Instability index51.54
Isoelectric point7.13
Molecular weight111330.75
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21227
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.99|      21|      27|     277|     303|       1
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  277-  303 (31.38/33.19)	LGVDESdgvKSWRPgkaLIEWLHSCLD
  307-  327 (38.61/22.37)	LLVDED...KCRVP...FYELLRSGLQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     288.63|      89|     289|     597|     692|       2
---------------------------------------------------------------------------
  597-  692 (144.93/92.95)	WSLNT......TTREYLNNEQLQKGKQIDEWwrQASKGDRMVDYMNMDDRSIGMFWVVSY.TMAQPACE...TVINWLSAAGVAESLPGTNLQsneRlmVMREVSP
  885-  983 (143.70/75.53)	WSDETlrffppLLRDFLITRIDKRGLAIQAW..QQAETTVINQCTQLLSPSADPTYVMTYiSHSFPQHRkylCAGAWILMQGHPENINSVNLA...R..VLREFSP
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     132.78|      35|     222|     151|     185|       3
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  118-  140 (23.24/ 7.52)	...............LRSLCTIG.......H.INWDSFLPSllSSV
  151-  185 (61.85/30.41)	SQAMPAVSSQ..SGMLQSSNNIP.......HSSNFQSSNPA..SPL
  375-  418 (47.69/22.01)	SQTTPSVSGEavASLRYSPITYPsvlgeplHGEDLATSIPK..GSL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     194.18|      63|     323|     435|     518|       4
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  444-  518 (99.17/111.90)	LLvaPCYRspSQGPTPGAVFtsemicegTIDRIVELLKLTNSDINCWQ..EWLVFSDIF....FFLIK...SGCVDFVDFVDKL
  776-  847 (95.01/57.41)	LL..PLYR..YQGKSKALMY........DVTKIISALKSKRGDHRVFRlaENLCMNLILslrdFFLVKregKGPTEFTETLNRI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21227 with Med23 domain of Kingdom Viridiplantae
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