<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21215

Description Mediator of RNA polymerase II transcription subunit 16
SequenceMSQVKESDDEPVALSLESDKPEIGSIESIEEDEEEEEEEEPVDKPGDPMEEDSVSPAAVFCIRLKQPRSNLQHKMSVPELCRNFSAVAWCGKLNAIACASETCARIPSSNANPPFWIPIHIVIPERPTECAVFNVNADSPRDSVQFIEWSPTSCPRALLIANFHGRITIWTQPSQGPANLVRDASRWQREHEWQQDIAVVTKWLSGVSPYRWLSSKSSAASNAKSTFEEKFLSQQSQNSARWPNFLCVCSVFSSGSVQLHWSQWPPNQNSAAPKWFQTSKGLLGAGPSGIMAADAIITDSGAMHVAGVPIVNPSTVVVWEVTPGLGNGFQLARLFNIRSKTRAKADDPDFSDTVPLHCSPVSNFSAYVSPEAAAQSATTTTWGSGVTAVAFDPTRGGSVIAVVIVEGQYMSPYDPDEGPSITGWRVQRWESSLQTVVLHQIFGNPTSSFGGQAPMQTVWLSKVDTSIQPTNDFKSHQAAASGATSDARKTTDSSLEKSKRVSFDPFDLPSDVRTLARIVYSAHGGEIAVAFLRGGVHIFSGPNFAPVDNYQINVGSAIATPAFSSTSCCSASVWHDSGKDRTVLKIIRVLPPAVSSSQVKANSSTWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVYLNSVIAVLDADFHSLPSTQHRQQYGPSLDRIKCRLLEGTNAQEVRAMVLDMQARLLLDMLGKGIESALINPSALVAEPWQASGETLSGIDPEAMAVEPALVPNIQAYVDAVLDLASHFITRLRRYASFCRTLASHAGSAGTGSNRNMVASPTQSSASPATSQAGQSGTTTSTGNTQMQAWVQGAIAKISSTSDGVPNSTPNPISGPSSFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRTQLPRFVGGAQRNTDANMQKPQPGAPGKVEEVSSVTVKSSSTMVRQDEGQVARAGQIIPGAKGAEEGPAGRSRLGAGNAGQGYTFEEVKVLFLILMDLCRRTATLAHPLPVSQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPICRICPGLEVQMLLVCYSES
Length1053
PositionTail
OrganismPrunus yedoensis var. nudiflora
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Rosaceae> Amygdaloideae> Amygdaleae> Prunus.
Aromaticity0.07
Grand average of hydropathy-0.164
Instability index47.43
Isoelectric point5.60
Molecular weight113439.43
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21215
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     290.68|      95|     107|     287|     393|       1
---------------------------------------------------------------------------
  287-  358 (96.92/55.55)	....................................P.......SGIMAADAIITDSGAMHVAGVPIVNPStVVVWEVtPGLGNGFQ...LARLF.NIRSKTRAKAD.DPDFSDTVPLHC
  359-  467 (135.43/90.08)	SPVSNfSAYVSPEAAAQSATTTTWGSgvtavafdptR.......GGSVIAVVIV..EGQYMSPYDPDEGPS.ITGWRV.QRWESSLQtvvLHQIFgNPTSSFGGQAPmQTVWLSKVDTSI
  791-  848 (58.33/26.92)	SPTQS.SASPATSQAGQSGTTTSTGN...........tqmqawvQGAIAKISS.TSDGVPNSTPNPISGPS.................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     244.55|      80|     177|     472|     558|       2
---------------------------------------------------------------------------
  472-  558 (121.74/111.69)	DFksHqaaaSGATSDARKTTDSSLEKSKRVSFDPFDlPSDVRTL.....ARIVYSAHGGEIAVAFLRGGVHI.....FSGPNFAPVDNYQINVGSAI
  652-  741 (122.81/91.42)	DF..H....SLPSTQHRQQYGPSLDRIKCRLLEGTN.AQEVRAMvldmqARLLLDMLGKGIESALINPSALVaepwqASGETLSGIDPEAMAVEPAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.90|      13|     112|     758|     770|       4
---------------------------------------------------------------------------
  758-  770 (26.05/15.54)	HFITRLRRYASFC
  873-  885 (26.85/16.20)	HFLHRLCQLLLFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.42|      11|      27|       5|      21|       5
---------------------------------------------------------------------------
    5-   21 (15.20/21.28)	KESDDEPValslesDKP
   35-   45 (21.21/12.17)	EEEEEEPV......DKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.73|      11|      26|     103|     114|       6
---------------------------------------------------------------------------
  103-  114 (18.25/15.83)	CArIPSSNANPP
  130-  140 (21.48/12.84)	CA.VFNVNADSP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21215 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GTGSNRNMVASPTQSSASPATSQAGQSGTTTSTGNTQ
2) MSQVKESDDEPVALSLESDKPEIGSIESIEEDEEEEEEEEPVDKPGDPMEE
781
1
817
51










Molecular Recognition Features






MoRF SequenceStartStop




1) MSQVKESDDEPVALSLESDKPEIGSIESIEEDEEEEEEEE
1
40