<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21194

Description Mediator of rna polymerase ii transcription subunit 34
SequenceMGRTEELFEELMNVEVELHDVQVIFLLRALLSCAPRRWPLLQRPHRLKLVGPKLFQAASDKAVKHMGTVAPSSSANGSSHSDISSPSSIVLCPSSMAVASEAAPAKAGGVISRPPASDGPSSIASSSSPVLRCAEVTLQAPSSEEIVVHAPIDVTAGPTIPVNICRQGFHALFLPATLLAFLDIPIAAGSKEKVHIEDACPISSRIGGGDMSFWMEEDKLLNFEKFLGVSFEGKEDRVLELLREIEQQSFYDGAGKELGQGVKQNNLGGCSGVPEKGPAGNAGDIFLIWDDRSLEVNEIKKGVFSLAALVKDRADFGSFAYLARWMQREGVRAPFRFKNMWLKVPRFGDKVKEWWTSYGVSGTPSFRLSKKLKLLKGDIIRWNKEVFGRVDVKMRELMHELGELERGEGARELDGSEKARLGEVKREIVELAIAQETSWRQKSRALWLKEGDSNTKFFHRVAVANRRRNFIESLAVDGVRIEGEEEVKGAIVGFYENYTKNQIKLLLDRQEKLHERQSELKALLESCESSSGPGDDNAAVSVDDWSRLFVWDSQADDIRFNVFGISKYRANQREIINAIMSGRDVLVIMAAGGGKSLCYQLPAVLRDGMALVVSPLLSLIQDQVMGLAALGIPAFMLTSTTSKENEKFIYKALEKGDDELKILYVTPEKISKSKRFMSKLEKCHHAGRLSLISIDEAHCCSQWGHDFRPDYKNLGILKTQFPNVPVIALTATATKKVQDDLMEMLRIPRCVKFVSSVNRPNLYYMVREKSSVGKTVVDEIAEYIRTSYPNNESGIVYCFSRKECEQVAQELRERGISADHYHADMDVNAREKVHLRWSSGKLQVIVGTVAFGMGINKPDVRFVVHHSLSKSMETYYQESGRAGRDGLPSECVLFFRPADVPRQSSMVFYENSGLKNLYDIVRYCQSKRECRRSAFFQHFAEPLQECNGMCDNCAFSNEVKELDVSSHAKLIVSMLKDIQENDQRITMLQLVEKLKVNQKNLGSDLKKDELEQLVIKLILDHVLKEEYQHTAYATNAYVTVGPLGMQVLQGKEIITVEMSTRQSRTSSSTRSSKRERSSGLDDKLGELRKELASIHGGIFPHSVLSMQQISTLTAQKPKSIEELEKIIGKLKTEKYGSRILEEIASYKSDPQQDADGSKESKGNAVKKLKTKKALVVLESSEDEA
Length1184
PositionUnknown
OrganismNicotiana attenuata (Coyote tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy-0.329
Instability index46.96
Isoelectric point7.91
Molecular weight132228.92
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21194
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     307.89|     104|     154|     209|     320|       1
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  209-  320 (160.66/138.88)	GDMSFWMEED.KLL..NFEKFLGVSFeGKED.RVLELLREIEQQSFYDGAgKELgQGVKQNNLGGCS.GVPEKGPAGNAGdifliWDDRS....LEVNEIKKGVFSLAALVKDRADF.GSFA
  362-  475 (147.22/102.66)	GTPSFRLSKKlKLLkgDIIRWNKEVF.GRVDvKMRELMHELGELERGEGA.REL.DGSEKARLGEVKrEIVELAIAQETS.....WRQKSralwLKEGDSNTKFFHRVAVANRRRNFiESLA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     352.62|     117|     150|     747|     882|       2
---------------------------------------------------------------------------
  681-  808 (103.64/109.83)	.............................EKCH...HAGRLSLISIDEAhccsqWGhdfrpdyknLGILKtqfPNV.PVIaLTATATKKVQDDLME.....mlrIP.RCVKFVSSVNRPNLYYMVREKSSVGKTVVDeiaeyirtsypnnesgIV.YCFSRKECEQVA
  809-  934 (185.66/155.30)	QELRERGISAdhyHADM......DVNAR.EKVHLRWSSGKLQVIVGTVA.....FG.........MGINK...PDV.RFV.VHHSLSKSMETYYQESGRAgrdgLPsECVLFFRPADVPRQSSMVFYENSGLKNLYD................IVrYCQSKRECRRSA
  957- 1033 (63.32/38.18)	NEVKELDVSS...HAKLivsmlkDIQENdQRITMLQLVEKLK..VNQKN.....LG.........SDLKK...DELeQLV.IKLILDHVLKEEYQHTAYA....................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     198.32|      46|      47|     107|     152|       3
---------------------------------------------------------------------------
   67-  103 (53.51/30.12)	..GTVA.PSSSANGSSHSDISSP....SSIVL.CPSSMAVASE..A.A
  107-  152 (76.48/46.15)	AGGVISRPPASDGPSSIASSSSPVLRCAEVTLQAPSSEEIVVH..API
  156-  202 (68.32/40.46)	AGPTIPVNICRQGFHALFLPAT.LLAFLDIPIAAGSKEKVHIEdaCPI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21194 with Med34 domain of Kingdom Viridiplantae
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