<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21192

Description Mediator of rna polymerase ii transcription subunit 33a
SequenceMAPMVSSVQIQSNLWDGVMELTKSAQQKGTDPLMWAIQLSSNLNSAGLSMPSTDVANLLVSHICWANNVPIAWKFLEKALTLRVVPPMFVLALLSTRVIPARRSYPVAYRLYMELLKRYAFSLASLINGPNYQKIMEAINDALHLYQIFGLQGSESGLIVVEFVFAIVWELLDASLDDEGLMELTAEKKSRWPITSQDMGLNNHDGFAGGRTEKHEGLCKMNTVMAIEIIGEFFRDKVTSAILYLARKNMPGHWESFTQNLRLLVSNSSALRNSKNISPEALLQLTSDNHVVLSRKRKTSSQKKFHAVVASGSLASSADQCHGASPSVLWLPFDLFLEDTIDGSQVAATSAAETLTGLVKALQAVNSTTWQDTFLGLWIAALRLVNRERDPSEGPVPRLDTCLCLLLSITPLAIANLIEEEERNCSSTNQTKESSRKRHQDLLSSLQQLDDYEGLLTPPLPAAPLANQAAAKAMMFLSGLRVGSGYFEGMSLNDMPVNCAGNLRHLIVEACIARNILDTSAYLWPGYVKGRCDQVPRSVSGQMPGWSSLMKGSPLTPPMVSSLVSTPASSLAEIEKIYDIAVNGSDDDKISAATILCGASLARGWNIQEHTVLFITRLLSPPVPANYSGTESHLIGYARFLNVLLIGVSSIDCVQIFSLHGLVPQLAGALMPICEAFGSCAPNVTWIVMSEEISSHAIFSNAFTLLLKLWRFDQPPRENVMDVVPVGSRLTPEYLLLVRNSQLASSDDLQKDQSKIKRLSRLSSPLSGEPIFMDSFPKLKLWYRQHQACIGSPLSGLLPGTPVHQIVEALLNFMFRKINRTGQSLAPTTSGSSSSSGPGNEDVFLHLKLPAWDILEAVPFVLDAALTACAHGRLSPRELATGLKDLADFLPASLATMVSYFSAEVTRGIWKLASMNGTDWPSPAANLATVEQQIKKILAATGVNVPSLTVGGNSPATLPLPLAALVSLTITYKLDRSTDRFLNLMGPALSNLATACPWPCMPVMVALWAQKVKRWSDFLVFSASRTVFHHNSDAVVQLLRMCFAATLGLTTSSIASNGGVGALLGHGFGSHFSGGISPVAPGILYLRVHRAVRNAMFMTEEVVSLLMHFVRDIASSGLPAEKLEKLKKSKYGMRYGQVSLAAAMTRVKLAASLGASLVWITGGVALVQSLIKETLPSWFISAHGSEPSGGMSGGLVAMLGGYALAYFAVLSGTFAWGVDSSSPASKHRSIILGGHLEFLASALDGKISLGCNKATWRAYVSGFVSLMVGSTPGWMLEVDVDVLKRLSTGLKQWNEEELALALLGSSGVGAMGTAAEMIIESGFNFVR
Length1327
PositionTail
OrganismNicotiana attenuata (Coyote tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.07
Grand average of hydropathy0.172
Instability index46.73
Isoelectric point7.57
Molecular weight143413.21
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21192
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.46|      30|      32|    1182|    1212|       1
---------------------------------------------------------------------------
 1182- 1212 (50.71/37.42)	AHGSEPSGGMSGGLVAMLGGYaLAYFA.VLSG
 1215- 1245 (48.75/30.79)	AWGVDSSSPASKHRSIILGGH.LEFLAsALDG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     126.04|      33|      33|     682|     714|       2
---------------------------------------------------------------------------
  682-  714 (60.85/37.74)	P..NVTWIVMSEEISSHAIFSNAFTLLLK...LW.RFD..Q
  716-  750 (30.70/15.19)	PreNVMDVV...PVGSR..LTPEYLLLVRnsqLA.SSDdlQ
  762-  787 (34.50/18.03)	.........LSSPLSGEPIFMDSFP.KLK...LWyRQH..Q
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.06|      12|      29|       3|      14|       3
---------------------------------------------------------------------------
    3-   14 (21.31/ 9.73)	PMVSSVQIQSNL
   32-   43 (22.76/10.81)	PLMWAIQLSSNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.25|      27|      34|      51|      83|       4
---------------------------------------------------------------------------
   51-   77 (50.25/41.26)	PSTDVANLLVSHICWA.NNVPIAWK.FLE
   86-  114 (40.01/19.64)	PPMFVLALLSTRVIPArRSYPVAYRlYME
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.68|      11|      30|     338|     348|       5
---------------------------------------------------------------------------
  338-  348 (18.87/10.15)	EDTIDGSQVAA
  371-  381 (20.81/11.94)	QDTFLGLWIAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.42|      26|      34|     442|     467|       6
---------------------------------------------------------------------------
  442-  467 (44.86/22.38)	LLSSLQQLDDY.EGLLTPPLPAAPLAN
  476-  502 (43.56/21.54)	FLSGLRVGSGYfEGMSLNDMPVNCAGN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     157.69|      28|      29|     864|     891|       7
---------------------------------------------------------------------------
  862-  889 (44.25/19.76)	LD..............AALTACAH.......GRLSPREL...ATGLKDLADF
  890-  915 (38.87/16.58)	LP..............ASL.ATMV.......SYFSA.EV...TRGIWKLASM
  920-  957 (22.72/ 7.04)	WPspaanlatveqqikKILAAT.........GVNVP.SL...TVGGNSPAT.
  958-  995 (27.45/ 9.84)	LP..............LPLAALVSltityklDRSTDRFLnlmGPALSNLATA
  996- 1018 (24.40/ 8.03)	CP..........wpcmPVMVAL................W...AQKVKRWSDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.09|      17|      25|     173|     189|      10
---------------------------------------------------------------------------
  173-  189 (27.43/21.61)	DASLDD.EGLMELTAEKK
  198-  215 (26.66/20.74)	DMGLNNhDGFAGGRTEKH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.78|      25|     524|     119|     153|      12
---------------------------------------------------------------------------
  119-  153 (28.78/66.97)	YAFSLASLINGpnyqkiMEAInDALhlyQIFGLQG
  637-  661 (46.00/43.84)	YARFLNVLLIG......VSSI.DCV...QIFSLHG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.68|      13|     524|     545|     557|      13
---------------------------------------------------------------------------
  545-  557 (26.88/14.61)	GWSSLMKG..SPLTP
 1067- 1081 (21.80/10.35)	GFGSHFSGgiSPVAP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21192 with Med33 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




NANANA