<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21183

Description Heat shock 70 kDa protein
SequenceMATKEGKAIGIDLGTTYSCVGVWLNDRVEIIPNDQGNRTTPSYVAFTDTERLVGDAAKNQVAMNPHNTVFDAKRLIGRRFTDPSVQSDMKLWPFKVLSGPGEKPMIEVSYKGEKKQFSAEEISSMILNKMKETAENFLGFKVKNSVVTVPAYFNDSQRQATKDAGAISGMNILRIINEPTAAAIAYGLDKKSSRIGEQHVLVFDLGGGTFDVSVLTIDEGIFEVKATAGDTHLGGEDFDNRLVNHFVSEFRRKHKKDLSGNARALRRLRTSCERAKRTLSSTTQTTIEVDSLFEGIDFYATITRARFEELCMDLFMKCMEPVEKCLRDAKIDKSKIHEVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILTGEGDEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQIFSTYSDNQPGVLIQVYEGERARTRDNNLLGKFELSGIPPAPRGVPQINVTFDIDANGILNVTAEDKTAGVKNKITITNDKGRLSKDEIDKMVRDAERYKAEDEEVKKKVEAKNGLENYAYNMRNTIKDEKIASKLSQEDKEKIEKGVQETIEWLDKNQLAEVDELEDKLKELEGICNPIIARMYQGGGGGGGAGGGVSMDDDQRPGGGTSGGASGTTGTGPKIEEVD
Length659
PositionUnknown
OrganismNicotiana attenuata (Coyote tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.454
Instability index32.57
Isoelectric point5.36
Molecular weight72273.01
Publications









Function






Annotated function

Probably plays a role in facilitating the assembly of
multimeric protein complexes inside the ER.



ECO:0000256	ARBA:ARBA00003955

GO - Cellular Component
endoplasmic reticulum lumen	GO:0005788	IEA:UniProtKB-SubCell

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
ATPase activity	GO:0016887	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21183
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     134.60|      33|      74|     496|     528|       1
---------------------------------------------------------------------------
  496-  528 (52.62/34.51)	EDK...TAGVKNKITITNDKGRLSK.DEIDKMVRD...AE
  533-  565 (40.74/25.04)	EDE...E..VKKKVEAKNGLENYAY.N.MRNTIKDekiAS
  570-  605 (41.23/25.43)	EDKekiEKGVQETIEWL.DKNQLAEvDELEDKLKE...LE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.39|      10|      21|     619|     628|       3
---------------------------------------------------------------------------
  619-  628 (20.68/ 9.57)	GGGGGGAGGG
  635-  644 (20.71/ 9.60)	QRPGGGTSGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.36|      17|      45|     426|     444|       7
---------------------------------------------------------------------------
  426-  442 (29.66/16.28)	PTKKEQIFSTYSDNQPG
  473-  489 (27.71/14.16)	PRGVPQINVTFDIDANG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.02|      17|      21|      37|      54|       8
---------------------------------------------------------------------------
   37-   54 (26.39/25.59)	NRT..TPSYVAFtDTERLVG
   59-   77 (26.62/19.57)	NQVamNPHNTVF.DAKRLIG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21183 with Med37 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MYQGGGGGGGAGGGVSMDDDQRPGGGTSGGASGTTGTGPKIEEVD
615
659










Molecular Recognition Features






MoRF SequenceStartStop




1) AGGGVSMDDDQRPGGGTSGGASGTTGTGPKIEEVD
625
659