<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21183

Description Heat shock 70 kDa protein
SequenceMATKEGKAIGIDLGTTYSCVGVWLNDRVEIIPNDQGNRTTPSYVAFTDTERLVGDAAKNQVAMNPHNTVFDAKRLIGRRFTDPSVQSDMKLWPFKVLSGPGEKPMIEVSYKGEKKQFSAEEISSMILNKMKETAENFLGFKVKNSVVTVPAYFNDSQRQATKDAGAISGMNILRIINEPTAAAIAYGLDKKSSRIGEQHVLVFDLGGGTFDVSVLTIDEGIFEVKATAGDTHLGGEDFDNRLVNHFVSEFRRKHKKDLSGNARALRRLRTSCERAKRTLSSTTQTTIEVDSLFEGIDFYATITRARFEELCMDLFMKCMEPVEKCLRDAKIDKSKIHEVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILTGEGDEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQIFSTYSDNQPGVLIQVYEGERARTRDNNLLGKFELSGIPPAPRGVPQINVTFDIDANGILNVTAEDKTAGVKNKITITNDKGRLSKDEIDKMVRDAERYKAEDEEVKKKVEAKNGLENYAYNMRNTIKDEKIASKLSQEDKEKIEKGVQETIEWLDKNQLAEVDELEDKLKELEGICNPIIARMYQGGGGGGGAGGGVSMDDDQRPGGGTSGGASGTTGTGPKIEEVD
Length659
PositionUnknown
OrganismNicotiana attenuata (Coyote tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.454
Instability index32.57
Isoelectric point5.36
Molecular weight72273.01
Publications

Function

Annotated function Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
GO - Cellular Component
endoplasmic reticulum lumen	GO:0005788	IEA:UniProtKB-SubCell
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
ATPase activity	GO:0016887	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP21183
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     134.60|      33|      74|     496|     528|       1
---------------------------------------------------------------------------
  496-  528 (52.62/34.51)	EDK...TAGVKNKITITNDKGRLSK.DEIDKMVRD...AE
  533-  565 (40.74/25.04)	EDE...E..VKKKVEAKNGLENYAY.N.MRNTIKDekiAS
  570-  605 (41.23/25.43)	EDKekiEKGVQETIEWL.DKNQLAEvDELEDKLKE...LE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.39|      10|      21|     619|     628|       3
---------------------------------------------------------------------------
  619-  628 (20.68/ 9.57)	GGGGGGAGGG
  635-  644 (20.71/ 9.60)	QRPGGGTSGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.36|      17|      45|     426|     444|       7
---------------------------------------------------------------------------
  426-  442 (29.66/16.28)	PTKKEQIFSTYSDNQPG
  473-  489 (27.71/14.16)	PRGVPQINVTFDIDANG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.02|      17|      21|      37|      54|       8
---------------------------------------------------------------------------
   37-   54 (26.39/25.59)	NRT..TPSYVAFtDTERLVG
   59-   77 (26.62/19.57)	NQVamNPHNTVF.DAKRLIG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP21183 with Med37 domain of Kingdom Viridiplantae

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