<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21181

Description Putative mediator of rna polymerase ii transcription subunit 26b
SequenceMAKSFGTLEKWRDYFRTANSDIFDIIEHAVMVAATDCPKEFKLRRDKIAEMLFTCKVTRCFGCDKVELAVPLANDDEGKNKNKSEFGGGFEAKESKANSSIDHHIELNVNQVSNYSYGDAEALTEEIEEETQTLGEVLRIKDIIDNSQHESAEVYECLRRLQLMALSVETLKATEIGKSVNALRKHSSKDIRHLSRTLIEDWKVLVDEWVNATAAFTGTESTPESMKVSVVDQEEEGLPSPPLDDLAFFAAQTTSMELSQFFDGMDDDGNPRNSGEFNENRGNGRKSSLDNQNNPVRKKQSADFFDAAPKERKGEQQKKQETVIKKQTPVMRPNKPSGGDSGPGRPIQPASEQKLKMSEMNFQQKSDKGTVQRRPVPTQQNKLRRSDEDAVQVKLEATKRKLQERYQEAENAKRQRTIQVMELHDIPKQGISNQGLGLKNPHTRPGNNNRHWANGRR
Length457
PositionUnknown
OrganismNicotiana attenuata (Coyote tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.06
Grand average of hydropathy-0.940
Instability index50.99
Isoelectric point6.38
Molecular weight51668.16
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP21181
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.18|      25|      26|     334|     359|       1
---------------------------------------------------------------------------
  334-  359 (41.52/27.40)	NKPSGGDSG..PGRPIqPASEQKLKMSE
  361-  387 (40.66/22.36)	NFQQKSDKGtvQRRPV.PTQQNKLRRSD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     179.77|      59|     183|      75|     141|       2
---------------------------------------------------------------------------
   75-  141 (80.52/68.11)	DDEGKNKNKSEFGggfEAKESKANSSIDHHielNvNQVSNYSYGD.AEALTEEIEEETQTLGEVLrIK
  266-  325 (99.25/58.02)	DDDGNPRNSGEFN...ENRGNGRKSSLDNQ...N.NPVRKKQSADfFDAAPKERKGEQQKKQETV.IK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.84|      19|      29|     215|     238|       3
---------------------------------------------------------------------------
  215-  238 (22.91/31.31)	AFTGTESTpeSMKVSvvdQEEEGL
  247-  265 (34.93/24.67)	AFFAAQTT..SMELS...QFFDGM
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP21181 with Med26 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) SQFFDGMDDDGNPRNSGEFNENRGNGRKSSLDNQNNPVRKKQSADFFDAAPKERKGEQQKKQETVIKKQTPVMRPNKPSGGDSGPGRPIQPASEQKLKMSEMNFQQKSDKGTVQRRPVPTQQNKLRRSDEDAVQVKLEATKRKLQERYQEAENAKRQRTIQVMELHDIPKQGISNQGLGLKNPHTRPGNNNRHWANGRR
259
457

Molecular Recognition Features

MoRF SequenceStartStop
1) KKQTPVM
2) PASEQKLKMSEMNF
325
349
331
362