<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21176

Description Mediator of rna polymerase ii transcription subunit 23
SequenceMYAERLISVRSAASETMSDQEMKYDLAASIQKGSLDWERALRILKHALRNTPSPDWWRRVLLVAPCHRLHAQAPTPGAVFTSEMVCEAAIERIVELLNFYLFFLLSAEINCWQEWLIFSDIFFFLVKSGCVDFVEFVDKLVLRLQEGDQQILRTNHVTWLLAQIIRVELVMNALNTDSRKVETTRKILSFHKEEKSSDPNNPQSILLDFISSCQNLRIWTLNTATREYLNNEQLQKGKQIDEWWRQVNKGERIMDYMNLDDRSIGMFWVVSYTMAQPACETVMHWLTSAGVTELLPGPNLQSNERLMVMREVSPLPISLLSGFSTNLCLKLAFQMEESMFSGQVLTMVSSSILYDFVNRLVGLPCPLFLVVLFALIMLFGRDIIRSHLLQLYYHTNSTLTESKPGAKVFSKIDLRSGYHQLRIRESDVPKIAFRTRYGHYEFLVMSFGLTNAPTAFMDLMNRVFRTYLDSFVIVFIDDILIYSRSQEEHEQHLRVVLQTPRDSQLYAKFSKCEFWLSSAAFLGHVVSAEGIQVDPKKIEAVKETTVINQCTQLLSPSADPTYVMTYINHSFPQHRQYLCAGAWILMHGHPENINCINLGRVLREFSPEEVTANIYTMVDVLLHHIHLELQRGHPLQDLMLKACGNLSIFIWTHELLPPDILLLALIDRDDNPHALRIVVCSL
Length682
PositionTail
OrganismNicotiana attenuata (Coyote tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.10
Grand average of hydropathy0.021
Instability index46.67
Isoelectric point6.10
Molecular weight78603.20
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21176
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.71|      17|      17|      95|     111|       1
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   95-  111 (29.73/18.99)	ELLNFYLFFLLSAEINC
  114-  130 (31.98/20.98)	EWLIFSDIFFFLVKSGC
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     230.47|      77|     290|     137|     314|       2
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   14-   91 (134.60/145.46)	SETMSDQEMKYDLAASIQKGSLdW..ERALR..ILKHALRNTPSPD.WWRRV.........................LLVAP.C....HRLHAQAPT...PGAVFTSE...MVCEAAIE
  197-  314 (95.86/128.42)	SDPNNPQSILLDFISSCQNLRI.WtlNTATReyLNNEQLQKGKQIDeWWRQVnkgerimdymnlddrsigmfwvvsyTMAQPaCetvmHWLTSAGVTellPGPNLQSNerlMVMREVSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.69|      18|     354|     136|     153|       5
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  136-  153 (30.91/21.43)	FVDKLVL..RLQEGDQQILR
  475-  494 (27.78/18.54)	FIDDILIysRSQEEHEQHLR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21176 with Med23 domain of Kingdom Viridiplantae
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