<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21172

Description Mediator of rna polymerase ii transcription subunit 19a
SequenceMDPDSKTFGRGPRELTGAVDLITHFKLLAHHEFFCKKPLSLSISDTHYLHNVVGDTEIRKGEGMQLDQLIQDTSSSKESNSRIQSFDLDVLREAFQLRETAPIDLPPSEKGIPTVAGKSKSESKDKEKKHKKHKDKDKEKDKEHKKHKHRHKDRSKDKDKEKKKDKTGHHDSGADHSKKHHEKKRKHDGEEDVNNVHKHKRNKHKSSKIDEIGAIRVAG
Length219
PositionHead
OrganismNicotiana attenuata (Coyote tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.03
Grand average of hydropathy-1.471
Instability index36.97
Isoelectric point9.51
Molecular weight25148.94
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21172
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.91|      15|      15|     157|     171|       3
---------------------------------------------------------------------------
  157-  171 (27.40/11.28)	D...KDKEKKKDKTGHHD
  175-  192 (22.51/ 7.98)	DhskKHHEKKRKHDGEED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.48|      12|      20|      49|      60|       4
---------------------------------------------------------------------------
   49-   60 (20.20/13.07)	LHNVVGDTEIRK
   66-   77 (19.28/12.21)	LDQLIQDTSSSK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21172 with Med19 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LRETAPIDLPPSEKGIPTVAGKSKSESKDKEKKHKKHKDKDKEKDKEHKKHKHRHKDRSKDKDKEKKKDKTGHHDSGADHSKKHHEKKRKHDGEEDVNNVHKHKRNKHKSSKIDEIGAIRVAG
2) VVGDTEIRKGEGMQLDQLIQDTSSSKESNSRIQS
97
52
219
85










Molecular Recognition Features






MoRF SequenceStartStop




1) SKDKEKKHKKHKDKDKEKDKEHKKHKHRHKDRSKDKDKEKKKDKTGHHDSGADHSKKHHEKKRKHDGEEDVNNVHKHKRNKHKSSKIDEIGAIRVA
123
218