<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21171

Description Mediator of rna polymerase ii transcription subunit 8
SequenceMEGAQDQQQQQPPRAVEGLNPAVQQQLNLESVKTRAISLFKAISRILEDFDAIARTNAVPKWQDILGQFSMVNLELFNIVEDIKKVSKAFVVHPKNVNAENAAILPVMLSSKLLPEMEVEDNAKREQLLHSMQNLSVASQIEKLKVRIDMIGAACESAEKVIADTRKAYFGTRQGPTLLPTIDKAQAAKIQEQESLLRTAVNHGEGLRVPGDQRHITSALPGHLVDVLTITDGPQSFADSSGTYLKNTPPFSSSNVNSQGALLQASGALRAAASPSGTTSFDTTTASPLPHANSPRSSANMMNTPSPQQQSLQQQQQQQQQQQQQLQQQQQQLQQRQKIMQLPQHQQQLLAQQQLRQASMPGLGQLHGQPQMQFSQPLGAQQFQGRQLASGAIHHGMGQSQLNQGNQLNRHLNQFSSPMNTALFNSAQSTPNSQMISNMSAMMTSQTLLPRTQFGMSGGTRNLAAANLSDQMFNMGGNNPGIMPIQQQQQHGTFGNMSQNTQNLQQGMMPLQNTPQTHPSFQQQRPQGQQ
Length530
PositionHead
OrganismNicotiana attenuata (Coyote tobacco)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Nicotianoideae> Nicotianeae> Nicotiana.
Aromaticity0.04
Grand average of hydropathy-0.626
Instability index60.51
Isoelectric point9.32
Molecular weight58154.78
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21171
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     233.58|      66|     172|     247|     317|       3
---------------------------------------------------------------------------
  247-  316 (105.53/55.78)	NTP.........................pFSSSNVNsQGAllQASGALR..AAASPSGTTSFDTTTASP........LPH...ANSPRSSAN....MM...NTPSPQQQSLQQQQ
  368-  453 (72.96/27.73)	GQPqmqfsqplgaqqfqgrqlasgaihhgMGQSQLN.QGN..QLNRHLN..QFSSPMNTALFNSAQSTP........NSQ...MISNMSA......MM.tsQTLLPRTQ......
  455-  525 (55.08/19.61)	..........................................GMSGGTRnlAAANLSDQM.FNMGGNNPgimpiqqqQQHgtfGNMSQNTQNlqqgMMplqNTPQ.THPSFQQQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      72.88|      21|      24|      33|      53|       5
---------------------------------------------------------------------------
   14-   32 (18.64/ 8.26)	..RAVeGLNPAVQQQL.NLESV
   33-   53 (32.70/19.92)	KTRAI.SLFKAISRILEDFDAI
   55-   69 (21.54/10.66)	RTNAV.PKWQ...DILGQF...
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21171 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SFADSSGTYLKNTPPFSSSNVNSQGALLQASGALRAAASPSGTTSFDTTTASPLPHANSPRSSANMMNTPSPQQQSLQQQQQQQQQQQQQLQQQQQQLQQRQKIMQLPQHQQQLLAQQQLRQASMPGLGQLHGQPQMQFSQPLGAQQFQGRQLASGAIHHGMGQSQLNQGNQLNRHLNQFSSPMNTALFNSAQSTPNSQMISNMSAMMTSQTLLPRTQFGMSGGTRNLAAANLSDQMFNMGGNNPGIMPIQQQQQHGTFGNMSQNTQNLQQGMMPLQNTPQTHPSFQQQRPQGQQ
236
530










Molecular Recognition Features






MoRF SequenceStartStop




NANANA