<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21149

Description Myosin heavy-chain kinase
SequenceMNISGWGQSVRATWPAPVITPQHYAAVAQAHIAAGDRVNAEASYNAAIQLATAELAKNPGHAREMALANISAEYAAFLAGENASDASSRQLPSVPANHSASAAHRPSFSSDSLPFSIQADNLEGKIVVQNCQGTINAPVQGTNNTVNVHYYSESRELLPQIKEMHTSVGELKTAYLDRFKEQQALELRSKKEPLAVLGQNIEAEYFTVWEEPGEIQDGLAMYVAPQATSLTDKKSFFDLNEAVTTYLAQANDSSQKTQVLLLRGEAGSGKSTFNRHLARRLWQDYSAASGEQPIPLYISLPTIDRPNKNLIGQYLSDKCGFSPEQINALRVSQRFILILDGYDEIPAEQRNLYADEKLDQWQAKILLSCRPEYLMEGYKNHLQPRGRSRVLLEYQLAPFSEQSIETYIHQYVKHTQAQWSAQAYQDRLARIPNVKELLGTPFLLKMALSVLPTLDEARPGQVALTRIKLYEQFVQTWFERSLARLKAIQPKLTGAQQKAFCSLEDEFIGHSQVFNTDFALAMAEAKTTVVEYSAIARRVMPQDKRYEQFLSNKDEEKNLLRFSALLIRQQQQYRFIHKSIQDYLVARAVWEELEEFTGFELSNRSEQLNGREDMRALWEVLDPSIQVDLNALLNRLNVVEDLAVQLFLAERVQQNRALVKPLLAWIKASTSQDGTSMAAANAITILVRAEIYLSKLNLSKVNVRGADLSYGIFDQTCFKGANLSEVKFRNAWLRGANLAEANLEKVDFGELPSLEMDEGVYDCRYSCNKDWLAVSTSNKVHLYQTQTLEIKKACVGKFRSIDFSSDSQVLALGSEDNKVILWHWDEEPGGQKEELVGHEDGVLSINFSKNNKYLASGGKDGQVNLWDLKEPKILYKLEKFMGRVNSVSFSQNNELLASGRSDGVVKIWKLEEEEVSILYNLKGHDDWGVNCVKFSRNNDFLASGGSDKKVKLWKVKDGNEFYTFEGHNGRITSIDFSKDDKILASGSADKTVKLWSIENGSILHTFEGHSSWVSSVNFSTDEQTSSSQSEVLASGSYDGTVRFWKVQHGEMPHVLTRQGSWVSSANLSSDGEYLSSGSEDGIVRLWNVKDGQGSAFHTFKGHDDEVLSLAFSLESKKLASGSKDKTVMLWDVDSKELSGKLEGHESAVLGVSFSPNSAFLVSGSEDGIVKIWDVENKNALYSFEEDSVIKSMNFSLDGKFLAFGNRSGAVKIWSVESQNVEDWIEKYTFHKHSEDVKAVQFSPNGKLVASGSDDKTVRLWEINEEKENSTFAEHGDGISSLNFSKHGSNLLSGSWDGTVKVWSIDEGKCSTTHAGFVGLAGFIVWQESSENNLGMVAGSRGSAVHIWQISKENTSDVGLYWASSQNELMVAGVFGESQGLDPMNARLLEQRQKTSRKNLRKSKELEFINNF
Length1411
PositionTail
OrganismMycoavidus cysteinexigens
KingdomBacteria
LineageBacteria> Proteobacteria> Betaproteobacteria> Burkholderiales> Burkholderiaceae> Mycoavidus.
Aromaticity0.09
Grand average of hydropathy-0.409
Instability index38.57
Isoelectric point5.54
Molecular weight157579.79
Publications
PubMed=29540638

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
kinase activity	GO:0016301	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21149
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            13|     718.96|      41|      41|     941|     981|       1
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  787-  830 (43.71/24.85)	TLE.I...KKACVG.KFRSIDFSSDSQ.......vLALGSEDNKVILWHWDEepG..G
  831-  872 (60.28/37.56)	QKE.E...LVGHED.GVLSINFSKNNK.......yLASGGKDGQVNLWDLKE..P..K
  873-  916 (53.08/32.04)	ILY.K...LEKFMG.RVNSVSFSQNNE.......lLASGRSDGVVKIWKLEE..EevS
  917-  959 (60.01/37.36)	ILY.N...LKGHDDwGVNCVKFSRNND.......fLASGGSDKKVKLWKVKD..G..N
  960- 1001 (66.31/42.20)	EFY.T...FEGHNG.RITSIDFSKDDK.......iLASGSADKTVKLWSIEN..G..S
 1002- 1050 (64.51/40.81)	ILH.T...FEGHSS.WVSSVNFSTDEQtsssqsevLASGSYDGTVRFWKVQH..G..E
 1051- 1094 (50.04/29.71)	MPH.V...LTRQGS.WVSSANLSSDGE.......yLSSGSEDGIVRLWNVKDgqG..S
 1095- 1135 (59.62/37.06)	AFH.T...FKGHDD.EVLSLAFSLESK.......kLASGSKDKTVMLWDV.D..S..K
 1136- 1178 (54.22/32.91)	ELSgK...LEGHES.AVLGVSFSPNSA.......fLVSGSEDGIVKIWDVEN..K..N
 1179- 1219 (52.55/31.64)	ALY.S...FE.EDS.VIKSMNFSLDGK.......fLAFGNRSGAVKIWSVES..Q..N
 1225- 1266 (58.23/35.99)	EKY.T...FHKHSE.DVKAVQFSPNGK.......lVASGSDDKTVRLWEINE..E..K
 1267- 1308 (61.09/38.19)	ENS.T...FAEHGD.GISSLNFSKHGS.......nLLSGSWDGTVKVWSIDE..G..K
 1309- 1353 (35.30/18.40)	CST.ThagFVGLAG.FIVWQESSENNL.......gMVAGSRGSAVHIWQISK..E..N
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.89|      28|      49|     531|     558|       2
---------------------------------------------------------------------------
  531-  558 (48.83/33.47)	EYSAIARRVMPQDKRYEQF.LSNKDEEKN
  561-  579 (23.89/12.24)	RFSALLIR...QQQQY.RF.IHKS.....
  582-  609 (39.18/25.26)	DY.LVARAVWEELEEFTGFeLSNRSEQLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      28.99|       9|      15|     370|     379|       3
---------------------------------------------------------------------------
  370-  379 (13.37/11.85)	RPEYLMEgYK
  387-  395 (15.62/ 7.76)	RSRVLLE.YQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.80|      22|      41|     169|     191|       4
---------------------------------------------------------------------------
  169-  191 (31.22/31.61)	GELKTAyLDRFKEQQALELRSKK
  213-  234 (37.57/30.92)	GEIQDG.LAMYVAPQATSLTDKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.40|      24|      48|     693|     722|       5
---------------------------------------------------------------------------
  697-  722 (37.78/27.33)	NLSKVN...VRGADLSYGIFDqtCFKGAN
  742-  768 (37.62/14.31)	NLEKVDfgeLPSLEMDEGVYD..CRYSCN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.64|      32|      50|     264|     295|       6
---------------------------------------------------------------------------
  264-  295 (58.10/31.96)	GEAGSGKSTFNRHL..ARRLWQDY.SAASGEQPIP
  312-  346 (48.54/25.61)	GQYLSDKCGFSPEQinALRVSQRFiLILDGYDEIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     132.79|      33|      33|     451|     483|       7
---------------------------------------------------------------------------
  421-  447 (38.17/26.23)	..........AQAYQDRLARIPNVKELL......GTPFLLKMA
  451-  483 (56.39/42.76)	L....PTLDEARPGQVALTRIKLYEQFV......QTWFERSLA
  485-  523 (38.23/26.28)	LkaiqPKLTGAQ..QKAFC..SLEDEFIghsqvfNTDFALAMA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21149 with Med16 domain of Kingdom Bacteria
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