<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21149

Description Myosin heavy-chain kinase
SequenceMNISGWGQSVRATWPAPVITPQHYAAVAQAHIAAGDRVNAEASYNAAIQLATAELAKNPGHAREMALANISAEYAAFLAGENASDASSRQLPSVPANHSASAAHRPSFSSDSLPFSIQADNLEGKIVVQNCQGTINAPVQGTNNTVNVHYYSESRELLPQIKEMHTSVGELKTAYLDRFKEQQALELRSKKEPLAVLGQNIEAEYFTVWEEPGEIQDGLAMYVAPQATSLTDKKSFFDLNEAVTTYLAQANDSSQKTQVLLLRGEAGSGKSTFNRHLARRLWQDYSAASGEQPIPLYISLPTIDRPNKNLIGQYLSDKCGFSPEQINALRVSQRFILILDGYDEIPAEQRNLYADEKLDQWQAKILLSCRPEYLMEGYKNHLQPRGRSRVLLEYQLAPFSEQSIETYIHQYVKHTQAQWSAQAYQDRLARIPNVKELLGTPFLLKMALSVLPTLDEARPGQVALTRIKLYEQFVQTWFERSLARLKAIQPKLTGAQQKAFCSLEDEFIGHSQVFNTDFALAMAEAKTTVVEYSAIARRVMPQDKRYEQFLSNKDEEKNLLRFSALLIRQQQQYRFIHKSIQDYLVARAVWEELEEFTGFELSNRSEQLNGREDMRALWEVLDPSIQVDLNALLNRLNVVEDLAVQLFLAERVQQNRALVKPLLAWIKASTSQDGTSMAAANAITILVRAEIYLSKLNLSKVNVRGADLSYGIFDQTCFKGANLSEVKFRNAWLRGANLAEANLEKVDFGELPSLEMDEGVYDCRYSCNKDWLAVSTSNKVHLYQTQTLEIKKACVGKFRSIDFSSDSQVLALGSEDNKVILWHWDEEPGGQKEELVGHEDGVLSINFSKNNKYLASGGKDGQVNLWDLKEPKILYKLEKFMGRVNSVSFSQNNELLASGRSDGVVKIWKLEEEEVSILYNLKGHDDWGVNCVKFSRNNDFLASGGSDKKVKLWKVKDGNEFYTFEGHNGRITSIDFSKDDKILASGSADKTVKLWSIENGSILHTFEGHSSWVSSVNFSTDEQTSSSQSEVLASGSYDGTVRFWKVQHGEMPHVLTRQGSWVSSANLSSDGEYLSSGSEDGIVRLWNVKDGQGSAFHTFKGHDDEVLSLAFSLESKKLASGSKDKTVMLWDVDSKELSGKLEGHESAVLGVSFSPNSAFLVSGSEDGIVKIWDVENKNALYSFEEDSVIKSMNFSLDGKFLAFGNRSGAVKIWSVESQNVEDWIEKYTFHKHSEDVKAVQFSPNGKLVASGSDDKTVRLWEINEEKENSTFAEHGDGISSLNFSKHGSNLLSGSWDGTVKVWSIDEGKCSTTHAGFVGLAGFIVWQESSENNLGMVAGSRGSAVHIWQISKENTSDVGLYWASSQNELMVAGVFGESQGLDPMNARLLEQRQKTSRKNLRKSKELEFINNF
Length1411
PositionTail
OrganismMycoavidus cysteinexigens
KingdomBacteria
LineageBacteria> Proteobacteria> Betaproteobacteria> Burkholderiales> Burkholderiaceae> Mycoavidus.
Aromaticity0.09
Grand average of hydropathy-0.409
Instability index38.57
Isoelectric point5.54
Molecular weight157579.79
Publications
PubMed=29540638

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
kinase activity	GO:0016301	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21149
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            13|     718.96|      41|      41|     941|     981|       1
---------------------------------------------------------------------------
  787-  830 (43.71/24.85)	TLE.I...KKACVG.KFRSIDFSSDSQ.......vLALGSEDNKVILWHWDEepG..G
  831-  872 (60.28/37.56)	QKE.E...LVGHED.GVLSINFSKNNK.......yLASGGKDGQVNLWDLKE..P..K
  873-  916 (53.08/32.04)	ILY.K...LEKFMG.RVNSVSFSQNNE.......lLASGRSDGVVKIWKLEE..EevS
  917-  959 (60.01/37.36)	ILY.N...LKGHDDwGVNCVKFSRNND.......fLASGGSDKKVKLWKVKD..G..N
  960- 1001 (66.31/42.20)	EFY.T...FEGHNG.RITSIDFSKDDK.......iLASGSADKTVKLWSIEN..G..S
 1002- 1050 (64.51/40.81)	ILH.T...FEGHSS.WVSSVNFSTDEQtsssqsevLASGSYDGTVRFWKVQH..G..E
 1051- 1094 (50.04/29.71)	MPH.V...LTRQGS.WVSSANLSSDGE.......yLSSGSEDGIVRLWNVKDgqG..S
 1095- 1135 (59.62/37.06)	AFH.T...FKGHDD.EVLSLAFSLESK.......kLASGSKDKTVMLWDV.D..S..K
 1136- 1178 (54.22/32.91)	ELSgK...LEGHES.AVLGVSFSPNSA.......fLVSGSEDGIVKIWDVEN..K..N
 1179- 1219 (52.55/31.64)	ALY.S...FE.EDS.VIKSMNFSLDGK.......fLAFGNRSGAVKIWSVES..Q..N
 1225- 1266 (58.23/35.99)	EKY.T...FHKHSE.DVKAVQFSPNGK.......lVASGSDDKTVRLWEINE..E..K
 1267- 1308 (61.09/38.19)	ENS.T...FAEHGD.GISSLNFSKHGS.......nLLSGSWDGTVKVWSIDE..G..K
 1309- 1353 (35.30/18.40)	CST.ThagFVGLAG.FIVWQESSENNL.......gMVAGSRGSAVHIWQISK..E..N
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.89|      28|      49|     531|     558|       2
---------------------------------------------------------------------------
  531-  558 (48.83/33.47)	EYSAIARRVMPQDKRYEQF.LSNKDEEKN
  561-  579 (23.89/12.24)	RFSALLIR...QQQQY.RF.IHKS.....
  582-  609 (39.18/25.26)	DY.LVARAVWEELEEFTGFeLSNRSEQLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      28.99|       9|      15|     370|     379|       3
---------------------------------------------------------------------------
  370-  379 (13.37/11.85)	RPEYLMEgYK
  387-  395 (15.62/ 7.76)	RSRVLLE.YQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.80|      22|      41|     169|     191|       4
---------------------------------------------------------------------------
  169-  191 (31.22/31.61)	GELKTAyLDRFKEQQALELRSKK
  213-  234 (37.57/30.92)	GEIQDG.LAMYVAPQATSLTDKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.40|      24|      48|     693|     722|       5
---------------------------------------------------------------------------
  697-  722 (37.78/27.33)	NLSKVN...VRGADLSYGIFDqtCFKGAN
  742-  768 (37.62/14.31)	NLEKVDfgeLPSLEMDEGVYD..CRYSCN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.64|      32|      50|     264|     295|       6
---------------------------------------------------------------------------
  264-  295 (58.10/31.96)	GEAGSGKSTFNRHL..ARRLWQDY.SAASGEQPIP
  312-  346 (48.54/25.61)	GQYLSDKCGFSPEQinALRVSQRFiLILDGYDEIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     132.79|      33|      33|     451|     483|       7
---------------------------------------------------------------------------
  421-  447 (38.17/26.23)	..........AQAYQDRLARIPNVKELL......GTPFLLKMA
  451-  483 (56.39/42.76)	L....PTLDEARPGQVALTRIKLYEQFV......QTWFERSLA
  485-  523 (38.23/26.28)	LkaiqPKLTGAQ..QKAFC..SLEDEFIghsqvfNTDFALAMA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21149 with Med16 domain of Kingdom Bacteria


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




NANANA