<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21144

Description transcription elongation factor A protein 2
SequenceMGKEEEIARIARRLDKMVTKKSAEGAMDLLRELKAMPVTLHLLQSTRVGMSVNALRKQSSDEEVTTLAKSLIKSWKKLLDASDAKAGEQRSASLASPPSKDTSEAKVHSRKRPELPKTPSTPRMTTFPPTPVTCDAVRNKCREMLAAALQTDDDHVAIGADCEHLSAQIEECIFRDVGSTDVKYKNRVRSRISNLKDAKNPGLRRSVLRGAIAPQRIAEMTSEEMASDELKEIRKAMTREAIREHQMARAGGTHTDLFTCGRCKRKSCTYTQVQTRSSDEPMTTFVVCNECGNRWKVG
Length298
PositionUnknown
OrganismTrichechus manatus latirostris (Florida manatee)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Afrotheria> Sirenia> Trichechidae> Trichechus.
Aromaticity0.03
Grand average of hydropathy-0.647
Instability index58.07
Isoelectric point9.41
Molecular weight33174.72
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
translation elongation factor activity	GO:0003746	IEA:UniProtKB-KW
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21144
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.45|      19|     217|      58|      76|       1
---------------------------------------------------------------------------
   58-   76 (32.52/21.30)	QSSDEEVTTLA..KSLIKSWK
  276-  296 (32.93/21.65)	RSSDEPMTTFVvcNECGNRWK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.62|      18|      18|      82|      99|       2
---------------------------------------------------------------------------
   82-   99 (30.01/16.06)	SDAKAGEQRSASLASPPS
  103-  120 (31.61/17.23)	SEAKVHSRKRPELPKTPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.20|      11|      18|     136|     146|       3
---------------------------------------------------------------------------
  136-  146 (19.09/10.59)	AVRNKCREMLA
  157-  167 (19.11/10.60)	AIGADCEHLSA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21144 with Med26 domain of Kingdom Metazoa
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