<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21125

Description mediator of RNA polymerase II transcription subunit 24 isoform X2
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDQLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGIPAAREKQLAMCLQRLEKTLSSTKNRALLHIAKLEEASLHTSQGLGQGGTRANQPTASWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPAMLSVHSEQLHKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCTNFLLQECSKQGLLSEASMTNLVAKRTADREHAPQLKSAENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIHLNEFTTHGNEESTKPASVRALLFDISFLMLCHVAQTYGSEVILSESSTGAEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCSLSSYSSHKGQASSRQKKRHREDIEDYISLFPLDDMQPSKLMRLLSSNEEDANILSSPTDRSMSSSLSASQLHKVNMRDPLNRVLASLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
Length1008
PositionTail
OrganismTrichechus manatus latirostris (Florida manatee)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Afrotheria> Sirenia> Trichechidae> Trichechus.
Aromaticity0.07
Grand average of hydropathy-0.002
Instability index46.90
Isoelectric point6.51
Molecular weight112222.24
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21125
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.53|      22|      25|      96|     120|       1
---------------------------------------------------------------------------
   96-  120 (35.45/24.40)	ALLDIMDMFcdqLSCHGKAEECI..GL
  123-  146 (33.07/15.08)	ALLSALHWL...LRCTAASAERLreGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     156.60|      47|     181|     723|     776|       2
---------------------------------------------------------------------------
  723-  776 (73.21/62.01)	KRPIKEVLTDIFakVLEKGWVDSRSIHIfdtllHMGGVYWFCNNLIKELLKETR
  913-  959 (83.40/52.79)	RDPLNRVLASLF..LLISSILGSRTAGP.....HTQFVQWFMEECVDCLEQGSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.57|      23|      29|     327|     355|       3
---------------------------------------------------------------------------
  327-  349 (40.64/33.69)	FTF.LKIPQVLVKLKKYSHGD.KDF
  357-  381 (33.93/14.44)	FEFlLKLTPLLDKADQRCNCDcTNF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.44|      17|     186|     228|     245|       4
---------------------------------------------------------------------------
  228-  245 (28.29/21.86)	PQLRSqAEQC......GTLIRSIP
  412-  434 (24.15/13.22)	PQLKS.AENAniqpnpGLILRAEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     172.27|      54|      67|     500|     565|       6
---------------------------------------------------------------------------
  500-  558 (85.69/82.15)	ESTKPASVRALLFDISFLMLChvaQTYGSEVILSESSTGAEVpfFETWMQTCMPEEG..KI
  569-  624 (86.58/50.80)	DSTKVESLVALLNNSSEMKLV...QMKWHEACLSISAAILEI..LNAWENGVLAFESiqKI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     165.96|      48|     116|     669|     717|      10
---------------------------------------------------------------------------
  669-  717 (81.66/49.86)	LYSENTLQFYNERVVIMSSILEHMCADVlQQTATQIKFPSTGMDTMPYW
  787-  834 (84.30/47.75)	LYSIFCLDMQQVTLVLLGHILPGLLTDS.SKWHSLMDPPGTALAKLAVW
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21125 with Med24 domain of Kingdom Metazoa
Unable to open file!