<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP21044

Description mediator of RNA polymerase II transcription subunit 24 isoform X2
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHIAKLEEASLHTSQGLGQGGTRANQPTASWTAIEHCLLKLGEILANLSSPQLRSQAEQCGTLIRSIPTMLSVHSERLHKTGFPTVHAVVLLEGTVNLTGETQPLVEQLVMVQRMQHIPTPLFVLEIWKACFVGLIESPEGTGELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVSSAFEFLLKLTPLLDKADQRCNCDCTNFLLQECSKQGLLSEASTNNLMAKRKADREHAPQLKSDENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHRSEESTKAASVRALLFDISFLMLCHVAQTYGSEVILSESNTGGEVFFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEIKLVQMKWHEACLNISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWQSLMDPPGTALAKLAVWCALSSYSSHKGQASSRQKKRQREDIEDYISLFPLDDMQPSKLMRLLSSNEEDANILSSPTDRSMSSNLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFAQWFMEGCVDCLEQGGRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
Length1008
PositionTail
OrganismDelphinapterus leucas (Beluga whale)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Artiodactyla> Whippomorpha> Cetacea> Odontoceti> Monodontidae> Delphinapterus.
Aromaticity0.07
Grand average of hydropathy-0.008
Instability index46.23
Isoelectric point6.62
Molecular weight112050.85
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP21044
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     263.40|      81|     115|     635|     720|       1
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  635-  720 (126.35/105.53)	LAVCAVAWLVAHV..RMLGLDEREKSLQMIrQLagpLYSENTLQFYNERVVIMSSILEHMCADVlQQTATQIKFPSTGMDTMPYWNLL
  755-  837 (137.05/95.64)	LHMGGVYWFCNNLikELLKETRKEHTLRAV.EL...LYSIFCLDMQQVTLVLLGHILPGLLTDS.SKWQSLMDPPGTALAKLAVWCAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     160.65|      53|      67|     491|     557|       2
---------------------------------------------------------------------------
  491-  545 (84.01/77.14)	N.EFTTHRsEESTKAASVRALLFDISFLMLC....HVAQTYGSEVILSESNT..GGeVFFFE
  560-  619 (76.64/39.65)	NpDHPCFR.PDSTKVESLVALLNNSSEIKLVqmkwHEACLNISAAILEILNAweNG.VLAFE
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.37|      46|     266|      78|     126|       3
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   78-  126 (75.02/51.84)	VLTAISKF...D.DFSRD........LCVQALLDIMDMFCDrLSCHG.KAEECIGlcRALLS
  335-  393 (62.35/33.53)	VLVKLKKYshgDkDFTEDvssafeflLKLTPLLDKADQRCN.CDCTNfLLQECSK..QGLLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.16|      27|      50|     143|     169|       4
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  143-  169 (45.35/28.61)	REGLEAGTPAAGEKQLAMCLQRLEKTL
  196-  222 (47.81/30.57)	QGGTRANQPTASWTAIEHCLLKLGEIL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.56|      13|     115|     311|     323|       5
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  311-  323 (24.04/14.28)	GLI..ESPEGTGELK
  427-  441 (16.52/ 7.57)	GLIlrAEPTVTNILK
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.07|      33|     675|     223|     274|       7
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  223-  260 (48.05/65.89)	ANLSSPQLrsqAEQCGTLIR..SIPTMLSVHseRLHKTGF
  275-  309 (55.02/28.70)	LTGETQPL...VEQLVMVQRmqHIPTPLFVL..EIWKACF
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP21044 with Med24 domain of Kingdom Metazoa
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