<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20979

Description mediator of RNA polymerase II transcription subunit 24 isoform X1
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLALCLLRLEKTLSSTKNRALLHIAKLEEASLHTSQGLGQGGTRANQPTASWTAIEHSLLKLGEILASLSNPQLRSQAEQCGTLIRSIPTMLAVHSEQLHKTGYPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYCHGDKDFTEDVSCAFEFLLKLTPLLDKADQRCNCDCTKFLLQECSKQGLLSEASVTNLMAKRAADREHAPQLKSGENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHGNEELAKAASVRALLFDISFLMLCHVAQTYGSEVILSESSTGAQVPFFETWMQTCMPEEGKILNPDHPCFWPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCSNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASSRQKKRHREDIEDYISLFPLDDMQPSKLMRLLSSNEEDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLSLGRQVAAKAIAAL
Length1008
PositionTail
OrganismEnhydra lutris kenyoni
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Carnivora> Caniformia> Mustelidae> Lutrinae> Enhydra.
Aromaticity0.07
Grand average of hydropathy0.032
Instability index46.01
Isoelectric point6.49
Molecular weight111959.01
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20979
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     442.07|     118|     194|     162|     282|       1
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  113-  159 (41.97/25.07)	......................................................................................KAEECIGLCRAL..LSALH.WLLRCTAASAERLREGLEAGTPAAGEKQLA
  162-  282 (183.71/161.05)	LLRLEKTLSSTKNRAlLHIAK........LEEASLhtSQGLGQG..GTRANQPTASWTAIEH.SLLKLGEILASLS....NPQLRSQAEQCGTLIRSIPTMLAVHSEQLHKTGYPTVHAVVLLEGTMNLTGETQPL
  285-  356 (70.60/50.77)	QLMMVKRMQHIPTP..LFVLE........IWKACF...VGLIESpeGTE....ELKWTAF...TFLKIPQVLVKLKkychGDKDFTEDVSCA............................................
  360-  469 (145.78/115.54)	LLKLTPLLDKADQRC......ncdctkflLQECS...KQGLLSE..ASVTNLMAKRAADREHaPQLKSGENANIQP....NPGLILRAEP..TVTNILKTMDADHSKS..PEGLLGVL......GHM.LSGKSLDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     266.49|      81|     194|     566|     734|       2
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  566-  646 (136.58/196.58)	FWPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFES.IQKITDNIKGKVCSLAV.CAVAWLVAH
  761-  843 (129.91/53.35)	YWFCSNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSkWHSLMDPPGTALAKLAVwCALSSYSSH
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20979 with Med24 domain of Kingdom Metazoa
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