<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20939

Description mediator of RNA polymerase II transcription subunit 24 isoform X3
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHIAKLEEASSWTAIEHCLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHSEQLHKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTGELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVSSAFEFLLKLTPLLDKADQRCNCDCTNFLLQECSKQGLLSEASTNNLMAKRKADREHAPQLKSDENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHRSEESTKAASVRALLFDISFLMLCHVAQTYGSEVILSESNTGGEVFFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEIKLVQMKWHEACLNISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDAMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASSRQKKRQREDIEDYISLFPLDDMQPSKLMRLLSSNEEDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEDCVDCLEQGGRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
Length989
PositionTail
OrganismPhyseter macrocephalus (Sperm whale) (Physeter catodon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Artiodactyla> Whippomorpha> Cetacea> Odontoceti> Physeteridae> Physeter.
Aromaticity0.07
Grand average of hydropathy0.006
Instability index46.98
Isoelectric point6.45
Molecular weight110276.05
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20939
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.92|      25|      68|     471|     496|       1
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  471-  496 (37.90/32.73)	LN.EFTTHRsEESTKAASVRALLFDIS
  540-  565 (41.02/30.02)	LNpDHPCFR.PDSTKVESLVALLNNSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     313.76|     107|     221|      44|     159|       2
---------------------------------------------------------------------------
   44-  154 (172.76/132.03)	EALLEQAMIGPS....PNPLIL..................SYLKYAISSqMVSYSSVLTAISKFD....DFSRD........LCVQALLDIMDMFCDrLSCHG.KAEECIGlcRALLS..ALHWLLRCTAAS...AERLREGLEAG.TPAAG
  261-  408 (141.01/85.30)	QPLVEQLMMVKRmqhiPTPLFVleiwkacfvgliespegtGELKWTAFT.FLKIPQVLVKLKKYShgdkDFTEDvssafeflLKLTPLLDKADQRCN.CDCTNfLLQECSK..QGLLSeaSTNNLMAKRKADrehAPQLKSDENANiQPNPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     157.85|      47|     186|     704|     757|       3
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  704-  757 (73.31/66.62)	KRPIKEVLTDIFakVLEKGWVDSRSIHIfdtllHMGGVYWFCNNLIKELLKETR
  894-  940 (84.54/57.54)	RDPLNRVLANLF..LLISSILGSRTAGP.....HTQFVQWFMEDCVDCLEQGGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.84|      15|      73|     770|     784|       5
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  770-  784 (27.55/17.81)	SIFCL.DMQQVTLVLL
  845-  860 (24.29/14.81)	SLFPLdDMQPSKLMRL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20939 with Med24 domain of Kingdom Metazoa
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