<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20938

Description mediator of RNA polymerase II transcription subunit 24 isoform X1
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLQRLEKTLSSTKNRALLHIAKLEEASLHTSQGLGQGGTRANQPTASWTAIEHCLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHSEQLHKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTGELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVSSAFEFLLKLTPLLDKADQRCNCDCTNFLLQECSKQGLLSEASTNNLMAKRKADREHAPQLKSDENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHRSEESTKAASVRALLFDISFLMLCHVAQTYGSEVILSESNTGGEVFFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEIKLVQMKWHEACLNISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGMDAMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASSRQKKRQREDIEDYISLFPLDDMQPSKLMRLLSSNEEDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEDCVDCLEQGGRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
Length1008
PositionTail
OrganismPhyseter macrocephalus (Sperm whale) (Physeter catodon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Artiodactyla> Whippomorpha> Cetacea> Odontoceti> Physeteridae> Physeter.
Aromaticity0.07
Grand average of hydropathy-0.010
Instability index46.36
Isoelectric point6.55
Molecular weight112152.04
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20938
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     263.84|      81|     115|     635|     720|       1
---------------------------------------------------------------------------
  635-  720 (126.15/113.25)	LAVCAVAWLVAHV..RMLGLDEREKSLQMIrQLagpLYSENTLQFYNERVVIMSSILEHMCADVlQQTATQIKFPSTGMDAMPYWNLL
  755-  837 (137.68/103.30)	LHMGGVYWFCNNLikELLKETRKEHTLRAV.EL...LYSIFCLDMQQVTLVLLGHILPGLLTDS.SKWHSLMDPPGTALAKLAVWCAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     182.37|      58|      66|     500|     558|       2
---------------------------------------------------------------------------
  500-  558 (99.12/65.54)	ESTKAASVRALLFDISFLMLC....HVAQTYGSEVILSESNT..GGeVFFFETWMQTCMPEEGKI
  569-  632 (83.25/50.47)	DSTKVESLVALLNNSSEIKLVqmkwHEACLNISAAILEILNAweNG.VLAFESIQKITDNIKGKV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     115.24|      25|      66|      92|     116|       3
---------------------------------------------------------------------------
   92-  116 (45.63/30.90)	LCVQALLDIMDMFCDRLSCH.GKAEE
  120-  140 (35.03/21.82)	LC.RALLSALHWL...LRCT.AASAE
  160-  185 (34.57/21.42)	MCLQRLEKTLSSTKNRALLHiAKLEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.62|      36|      48|     244|     291|       5
---------------------------------------------------------------------------
  235-  275 (51.27/58.65)	EQCGTLIR..sIPTMLSVHseQLHKTGFptVHAVVLLEGTMNL
  284-  322 (61.35/35.45)	EQLMMVKRmqhIPTPLFVL..EIWKACF..VGLIESPEGTGEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.45|      16|     115|     208|     225|       8
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  208-  225 (24.12/23.47)	WTAIehCLLKLGEILANL
  324-  339 (29.33/19.93)	WTAF..TFLKIPQVLVKL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20938 with Med24 domain of Kingdom Metazoa
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