Description | Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MTSSQEPQYGGFSRFELELEFVQCLANPGYLQYLAMQKLFEKPDFVAYLGYLQYFKEPQYSKYLHHPGPTLRTLELLQNERFRRDVMSPELVNNLMVQGQRNAVPDKKD |
Length | 109 |
Position | Middle |
Organism | Periconia macrospinosa |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes> Pleosporomycetidae> Pleosporales> Massarineae> Periconiaceae> Periconia. |
Aromaticity | 0.14 |
Grand average of hydropathy | -0.618 |
Instability index | 42.51 |
Isoelectric point | 6.10 |
Molecular weight | 12870.54 |
Publications | PubMed=29679020 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro |
Binary Interactions |
Repeats | >MDP20781 No repeats found |
MoRF Sequence | Start | Stop |
1) PQYGGFS 2) QRNAVPD 3) RFRRDV | 7 100 81 | 13 106 86 |
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