<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20750

Description Uncharacterized protein
SequenceMAINEDFLPVQDKQKDTLAVSKSPLAALRISPVPTAQDRDNRSERPTVTARTRRARKRNTLAATKRPNGPGFDFDVDIDEKALEAPPQLAQDHVAFDDGDEEVIRRPSVSNEEDGSAVKRLATFLIESGKAMNVRYNVVDPLDDEKESGTGASNKKPLQISRTTKTRKETVMAVLSLKYHWLIKCQEDYAHDQIKYPGVEGVYNPLQIIRNRAIRAKYHEPAPPLRYANLPLACNVFSSHKKSGGRPWKMLWGIELNELVNDDAWRSQHWKELKNPKGELWFPDSRPPPRSVISFDTPTKPPKANRLHDKLWNETADSDSRVSSRSKSPSAKSIGKNIKQKARRLYGSTSSGANSNSDLDNSSTDPSKSHESLSKQKQSSVSKSESDSNGVHVFQVPRNLGSSGSSEAQRSQNDLPKITVDTALNDDVDTKNSAQHVEDSSVNRSRMNLDDVQITPLHARSQSENFKPNVLASAIPHVDAKDRKLSQAYNHGQYMEQQVTLHESFMTTIFPRVVDSTSTRLESILNNNINVLLHDIVSVNDSELPAHEAFYTGFLSECKSLMHLMNDKYAVKIDNLLSATDRSMGEINTSLSLDMKKVNEQLDKVNQSLFGSLVTTSIGDRERDVTFTDGGNYKILYFILENAIVTVLRLTWLVVNIYKFFLAILKIIWKLTSILFGIDTNIYQVLENFQEVFDKAIIQDKSRESLAVENLTLESDALNIIRLCKDLLSITRSLRESWCLDTMKVRPEGGDSRASDEDVQRVFEEFNRLTEKISALEKS
Length779
PositionHead
Organism[Candida] haemulonis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Clavispora> Clavispora/Candida clade.
Aromaticity0.06
Grand average of hydropathy-0.603
Instability index50.82
Isoelectric point6.81
Molecular weight87701.58
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20750
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.30|      15|      31|     238|     252|       1
---------------------------------------------------------------------------
  238-  252 (30.99/17.62)	SSHKKSGGRPWKMLW
  267-  281 (30.31/17.09)	SQHWKELKNPKGELW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      86.20|      16|      35|     326|     341|       2
---------------------------------------------------------------------------
  300-  314 (18.35/ 7.70)	.KPPKANRLHDKLWNE
  326-  341 (26.99/14.66)	SKSPSAKSIGKNIKQK
  363-  377 (23.40/11.77)	STDPS.KSHESLSKQK
  382-  395 (17.47/ 7.00)	SKSES.DSNGVHVFQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.88|      17|      58|     343|     359|       3
---------------------------------------------------------------------------
  343-  359 (30.84/15.19)	RRLYGSTSSGAN.SNSDL
  398-  415 (26.03/11.89)	RNLGSSGSSEAQrSQNDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     161.29|      52|      58|     432|     489|       4
---------------------------------------------------------------------------
  432-  489 (82.14/59.51)	NSAQHVEDssvnrsRMNLDDVQITPLHAR...SQSE......NFKPNVLASAIPHVDAKDRKLSQAY
  490-  550 (79.15/46.33)	NHGQYMEQ......QVTLHESFMTTIFPRvvdSTSTrlesilNNNINVLLHDIVSVNDSELPAHEAF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.93|      12|      40|      13|      24|       5
---------------------------------------------------------------------------
   13-   24 (20.20/15.41)	KQKDTLAVSKSP
   56-   67 (20.74/16.05)	RKRNTLAATKRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.74|      26|      31|     560|     586|       6
---------------------------------------------------------------------------
  560-  586 (40.70/34.12)	SL.MHLMNDKYAvKIDNLL..SATDRSMGE
  592-  620 (33.03/21.99)	SLdMKKVNEQLD.KVNQSLfgSLVTTSIGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.97|      45|      47|     140|     186|       7
---------------------------------------------------------------------------
  140-  186 (75.14/53.09)	DPLDDE.KESGT.GASNkkPLQISRTTKTRKETVMAVLSLKYHWL.IKCQ
  188-  235 (70.83/44.23)	DYAHDQiKYPGVeGVYN..PLQIIRNRAIRAKYHEPAPPLRYANLpLACN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20750 with Med22 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LAVSKSPLAALRISPVPTAQDRDNRSERPTVTARTRRARKRNTLAATKRPNGPGFDFDVDIDEKALEAPPQLAQDHVAFDDGDEEVIRRPSVSNE
2) PKGELWFPDSRPPPRSVISFDTPTKPPKANRLHDKLWNETADSDSRVSSRSKSPSAKSIGKNIKQKARRLYGSTSSGANSNSDLDNSSTDPSKSHESLSKQKQSSVSKSESDSNGVHVFQVPRNLGSSGSSEAQRSQNDLPKITVDTALNDDVDTKNSAQHVEDSSVNRSRMNLDDVQITPLHARSQS
18
276
112
463










Molecular Recognition Features






MoRF SequenceStartStop




NANANA