<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20738

Description Uncharacterized protein
SequenceMNNMPNAPMGGTWHSEQNPDERQKIISIVVQTLRDLQGSNFNEAAASKMAHDFEKYVFMKAPSRDDYLSAIKQKVHQMRGSVRNNSQGQNASNAQMGQRQQQPQQQQQQQQQQPPPFQAQAQAQAQAARAQQQQQQQQAQQQQSMGMGMNNDVSGQGMNFFPQNQMQMRNGMMPQQSPQQNHQQVPQAQINRPASQGMQQQNAPSQQQQSNAPAQQSAYPQQIQQLSAMIKNVPIPPVYLNKIPGLPPNVNTWARIYDLAQKKVIPPSSLPAIKEVHNAHLSIVMHQQQQRLAQRRMSNMNSGTGSGNAGAAAPANDQNTAQGNMNNMNSINSMNNMNGMNVNRQSQGSMNMQNQRMQQQQQQQAAFKNNNTNKAQGNQNNMQLPMGMQRPQQQQQQPQQNQQTPMMKQQQPQQQQAPGNQTNMGMANQNTGGQQQQAAGMKVPNFQITPQDMMDYQAEALAYLSRAQQDGKIPPNLDNNGKQSFIRKYIYHQKMTAWKNEQIKASKGSGGQMNMAQQQQQQQPQRTPQQSSMQMGNMNQGGFPQQQFQQQLNQQNQSQQSQQQPPSSHQAQQQPIGGMQQGMGQSQQSPMMGNLQQPNATPLMNQGPNQAMFSPVVQQKAPGQGPQANAAGLNAQQNQARRPQGVPPVTDEMKMKLKSLFDEVARGDSFQLKNHTMSLSDKDKLRVKELMVKINQQYTNVDHVLTYYYALTRDLGGTKKLIQMKFMTKNIIDNFQKGIYLAGPELLEKMVQHFQKYFDAVRKELTARRQQQQQQQPQAQKLESTSAQMSPAQQRPAMNQPSAQVPGQRPLSAMQPMQQGDQRFMAQNVPQNNQQNFGPPGMGQMPMTQNISPQQQHQQPPQQQAQQQAPPPSAQQHLANQRGPQQQQTQQQFARNATYGQLSQGQPDWSKAVNGPQRGANISPMPTAQSGTSPQLQTQTAPKTAAKGKKASTSGAAGRRKSTKAAGTMPTPGNSAPTPATLANAIKTPNSMPTPQVIQSTSNKGTPIDVSPNSDNKGANVMAKEPIVGDVFGANKVDSKLDKRRELSKSDPQQFFFAALSNLLETDKTESTNGTKAGVANGDHTKSPLSPNSAEWSCTVKPEAITSAFCQVDFIKDLTALEVLEECAKLVDRDAKKKEEEALNSKKREREEPDDIDLLFDESETKKVKTDDFDRFMYEPVEFDEWKQWLTGLQQTKV
Length1198
PositionTail
Organism[Candida] haemulonis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Clavispora> Clavispora/Candida clade.
Aromaticity0.05
Grand average of hydropathy-1.089
Instability index60.31
Isoelectric point9.74
Molecular weight133385.60
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20738
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.79|      20|      22|     849|     868|       2
---------------------------------------------------------------------------
  107-  128 (33.09/ 6.33)	QQQQQQQPPpfQAQAQAQAQAA
  853-  872 (40.69/10.08)	PQQQHQQPP..QQQAQQQAPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     273.89|      54|      55|     516|     570|       3
---------------------------------------------------------------------------
  409-  455 (59.84/12.67)	..QQQ...P.QQQQ.APGNQ...TNMGMAN.........QNTGG......QQQQAAGMKVPNFQIT..PQDMMD
  516-  570 (101.47/31.52)	AQQQQ...Q.QQPQ.RTPQQ...SSMQMGN.........MNQGGfPQQQFQQQLNQQNQSQQSQQQ..PPSSHQ
  571-  634 (59.40/12.49)	AQQQPiggM.QQGM.GQSQQ...SPM.MGNlqqpnatplMNQG..PNQAMFSPVVQQKAPGQGPQA..NAAGLN
  792-  844 (53.18/10.06)	AQQRP...AmNQPSaQVPGQrplSAMQ..P.........MQQG...DQRFMA....QNVPQNNQQNfgPPGMGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      74.30|      14|      15|     966|     979|       4
---------------------------------------------------------------------------
  966-  979 (28.54/15.94)	AGTMPTPGNSAPTP
  983-  995 (24.43/12.44)	ANAIKTP.NSMPTP
 1001- 1014 (21.33/ 9.80)	TSNKGTPIDVSPNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.99|      23|     293|      84|     106|       5
---------------------------------------------------------------------------
   84-  106 (45.13/12.39)	NNSQGQNASNAQMG.QRQQQPQQQ
  178-  200 (38.96/ 9.35)	PQQNHQQVPQAQIN.RPASQGMQQ
  377-  397 (35.90/ 7.84)	GNQNNMQLP...MGmQRPQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.41|      23|      29|     278|     302|       7
---------------------------------------------------------------------------
  278-  302 (38.28/23.97)	NAHLSivMHQQQQRLAQRRMSNMNS
  308-  330 (42.13/21.07)	NAGAA..APANDQNTAQGNMNNMNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.45|      13|      29|     231|     243|       8
---------------------------------------------------------------------------
  231-  243 (25.30/16.94)	KNVP.............IPPVYLNKI
  248-  273 (16.15/ 7.62)	PNVNtwariydlaqkkvIPPSSLPAI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.41|      30|      55|     874|     912|       9
---------------------------------------------------------------------------
  762-  791 (50.13/12.38)	RKELTARRQQQQQQQPQAQKLESTSAQMS...P
  875-  907 (49.28/23.38)	QQHLANQRGPQQQQTQQQFARNATYGQLSqgqP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.60|      18|      39|      22|      39|      14
---------------------------------------------------------------------------
   22-   39 (28.61/19.13)	RQKIISIVVQTLRDLQGS
   64-   81 (30.99/21.38)	RDDYLSAIKQKVHQMRGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.95|      10|     175|     220|     229|      17
---------------------------------------------------------------------------
  204-  213 (19.34/ 7.41)	PSQQQQSNAP
  220-  229 (18.61/ 6.78)	PQQIQQLSAM
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20738 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DKTESTNGTKAGVANGDHTKSPLSPNSAEWS
2) LQGSNFNEAAASKMAHDFEKYVFMKAPSRDDYLSAIKQKVHQMRGSVRNNSQGQNASNAQMGQRQQQPQQQQQQQQQQPPPFQAQAQAQAQAARAQQQQQQQQAQQQQSMGMGMNNDVSGQGMNFFPQNQMQMRNGMMPQQSPQQNHQQVPQAQINRPASQGMQQQNAPSQQQQSNAPAQQSAYPQQIQQLS
3) MNNMPNAPMGGTWHSEQNPDERQKIISIVVQT
4) RKELTARRQQQQQQQPQAQKLESTSAQMSPAQQRPAMNQPSAQVPGQRPLSAMQPMQQGDQRFMAQNVPQNNQQNFGPPGMGQMPMTQNISPQQQHQQPPQQQAQQQAPPPSAQQHLANQRGPQQQQTQQQFARNATYGQLSQGQPDWSKAVNGPQRGANISPMPTAQSGTSPQLQTQTAPKTAAKGKKASTSGAAGRRKSTKAAGTMPTPGNSAPTPATLANAIKTPNSMPTPQVIQSTSNKGTPIDVSPNSDNKGANVMAKEPIVG
5) TAWKNEQIKASKGSGGQMNMAQQQQQQQPQRTPQQSSMQMGNMNQGGFPQQQFQQQLNQQNQSQQSQQQPPSSHQAQQQPIGGMQQGMGQSQQSPMMGNLQQPNATPLMNQGPNQAMFSPVVQQKAPGQGPQANAAGLNAQQNQARRPQGVPPVTDEM
6) VIPPSSLPAIKEVHNAHLSIVMHQQQQRLAQRRMSNMNSGTGSGNAGAAAPANDQNTAQGNMNNMNSINSMNNMNGMNVNRQSQGSMNMQNQRMQQQQQQQAAFKNNNTNKAQGNQNNMQLPMGMQRPQQQQQQPQQNQQTPMMKQQQPQQQQAPGNQTNMGMANQNTGGQQQQAAGMKVPNFQITPQDMMDYQAEALAYLSRAQQDGKIPPNLDNNGKQSFIRKYIYHQ
1067
36
1
762
496
264
1097
227
32
1029
653
493










Molecular Recognition Features






MoRF SequenceStartStop




1) FDRFMYEPVEFDEW
2) SFIRKYIYHQK
1173
484
1186
494