<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20724

Description Mediator of RNA polymerase II transcription subunit 23 isoform 2
SequenceMALSMETQLQSIFEDVVKTEMIEEAFAGMFMDTPEDERTKLISCLGAFRQYWGTLPQESHDQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETSLLPPRMVCVALISSDSLEWERTQLWALTFKLIRKIIGGVDYKGVRDLLKAVLDKIQTIPTTVSSAIVQQLLAAREVVEYILDRNACLLPAYFAITEIRKLYPEGQLSHWLLGSLISDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPTTLRFPLRGMLPFDKDLFEPQTGLLRYVLEQPYSREMVCNMLGLNKQHKQRCPVLEEQLVDLVVYAMERSETEEHFDADVGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHSFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKTLGMSDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGSMRINLPGTNCMASGSVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSIALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIHGTWCKDILQTIMTFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMANENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGFRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVNDFVKENAPEHWLQSDWHNKHMSYHKKYPEKLYFEGLADQVNPPMQLQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRDRTNLKRKLVHAIMSSLKDNRTPGWCLSETYLKCGMNPREDNVWIPDDTYYCKLIGRLVDNILHYSDIEHPLNSVSPMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGKEVGNALLNVVLKSQPLVPRENITAWMNAIGLVITALPEPYWIVLHDRIVSVISSPALTSETEWAGYPFALLDFTACHQSYSEMNCSYVLALAHAVWHHSSIGQLSLIPKFLSETLKPVVQTEFQLLYVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDQHCQHLSYMDPICDFLYHIKYMYTGDSVKEQTPPHKCPAQTPR
Length1347
PositionTail
OrganismScophthalmus maximus (Turbot) (Psetta maxima)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Carangaria> Pleuronectiformes> Pleuronectoidei> Scophthalmidae> Scophthalmus.
Aromaticity0.10
Grand average of hydropathy-0.039
Instability index45.43
Isoelectric point6.77
Molecular weight154263.26
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20724
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.20|      36|     212|     172|     259|       1
---------------------------------------------------------------------------
  178-  218 (54.04/78.29)	NACL..LPAY.FAITEIRKLYP.....EGQLSHwlLGSLISdFVDsfRP
  964- 1007 (54.16/11.25)	NVCLrfLPVFdIVIHRFLELLPvskslETLLDH..LGGLYK.FHD..RP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.70|      20|     212|     899|     920|       3
---------------------------------------------------------------------------
  899-  920 (36.18/24.56)	PNDFRN...RVNDFvkENAPEHWLQ
 1106- 1128 (36.52/19.21)	PGPFPNcdwRFNEF..PNPAAHALH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.74|      10|      28|     139|     148|       5
---------------------------------------------------------------------------
  139-  148 (15.32/ 8.82)	RDLLKAVLDK
  168-  177 (16.41/ 9.92)	REVVEYILDR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      30|     345|     354|       6
---------------------------------------------------------------------------
  345-  354 (18.69/10.77)	IFFVLFQFAS
  378-  387 (19.45/11.54)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.49|      27|     527|     253|     279|      14
---------------------------------------------------------------------------
  253-  279 (48.72/28.76)	RFPLRGMLPFDKD.......LFEPQTGLLRYVLE
  284-  317 (39.77/22.16)	REMVCNMLGLNKQhkqrcpvLEEQLVDLVVYAME
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20724 with Med23 domain of Kingdom Metazoa
Unable to open file!