<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20721

Description Putative cyclin-dependent kinase 19-like
SequenceMKTYLWVKMDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGLERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFLEDPLPTTDVFAGCQIPYPKREFLNEDEPEEKTEKNQTQQHQQTTGQNQTQNQQQTTAQQAPSQQSSAQTNGTAGATGATAGGGLQHGQDQGPPNKKPRIGPSGASSGTGVLQSEYQHSGSRLGYQSNVQGSTQPQSTMGYSSSSQQSSQYTHQTHDNPQQPQQTSGDALGSPFLVGPHSVHYIIPTIDN
Length533
PositionKinase
OrganismScophthalmus maximus (Turbot) (Psetta maxima)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Carangaria> Pleuronectiformes> Pleuronectoidei> Scophthalmidae> Scophthalmus.
Aromaticity0.09
Grand average of hydropathy-0.684
Instability index48.32
Isoelectric point8.33
Molecular weight60384.53
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20721
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     122.96|      26|      98|     390|     415|       1
---------------------------------------------------------------------------
  390-  415 (43.56/23.15)	QNQTQNQQQTTAQQAPSQQSSAQTNG
  422-  441 (23.45/ 9.08)	ATAGGGLQHGQDQGPPNKKP......
  473-  491 (23.68/ 9.24)	QGSTQ.PQSTMGYSSSSQQS......
  492-  514 (32.26/15.24)	...SQYTHQTHDNPQQPQQTSGDALG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20721 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IPYPKREFLNEDEPEEKTEKNQTQQHQQTTGQNQTQNQQQTTAQQAPSQQSSAQTNGTAGATGATAGGGLQHGQDQGPPNKKPRIGPSGASSGTGVLQSEYQHSGSRLGYQSNVQGSTQPQSTMGYSSSSQQSSQYTHQTHDNPQQPQQTSGDALGSPFLVGPHSVHYIIPTIDN
359
533










Molecular Recognition Features






MoRF SequenceStartStop




1) GPPNKKPRIGP
435
445