<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20695

Description Putative mediator of RNA polymerase II transcription subunit 26-like
SequenceMTTVSATPQQMRDRLLRAIDSQSNICNMVAVMEVITGLEKYPITKEALEETRLGKLINDVRKKTKDEDLAKRAKKLLRNWQKLIEPGPAVAASALGSTNGSSHPCRTEASPPDISVSGKGVIDVKIRNDVHNTYSPKAEKSSSRKRRAELRESGVHLPEKISKMASYDISVSPPPTNGIAGSPDALPDQDVVPSPDRSRIENLDNDKINRIPVNAVKPRPSSPGVAKLPSTSSLIKVAVMQQQARLDEGGGGGGYYQAKSPRGVTTSPRSMKQDTVTKRSLVYAPKGPPVPSPSSRDSPLSSSQPVSSPAQASYAEKLPHSSHRSSMHWASSSEVPSHCPPQDASATLESPTASPSASLPPQNSELQRPTSEGAVAVSDDTDGSAAPNSEHKRRKYRSRDYSVNLDGQKIEDMTKPVRLKERRLTFDPVTGQIKHLVHKEPSQTEDFPIPDLSESRRRTESTVQQPAAPAPAPAPALVQVQVQIPAPAPGPSPNPFHQTNWKELSRNEIIQSYLNLQSNVLNSSGVQAPSAHFFMSEYLKREEQEIKESRKTHVLQADITVGDLPGVSREVTGEDLDRIHTQHWPGVNGCYDTMGTCKKKPCCRCCSFSKKKSYNVFLAQDHNSQVLKRDHIFPLVFPLNVMALTRTEAAAAWCGPVLRFLDDLAESREKRKTSLRPDHSSGLF
Length684
PositionUnknown
OrganismScophthalmus maximus (Turbot) (Psetta maxima)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Carangaria> Pleuronectiformes> Pleuronectoidei> Scophthalmidae> Scophthalmus.
Aromaticity0.04
Grand average of hydropathy-0.688
Instability index71.11
Isoelectric point9.23
Molecular weight74867.54
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20695
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     305.19|      52|      68|     273|     324|       1
---------------------------------------------------------------------------
   87-  144 (28.11/ 6.90)	....................GPAV.AAS........ALGST..NG.SSHPCrteASPPDISvsgkgvidvkirndvhntYSPKAEKSSSR
  152-  204 (43.09/14.42)	ES.GVhlpekISKMASYDISVSPPPTNG........IAGSPdaLP.DQDVV...PSPDR.S..................RIENLD.....
  205-  232 (37.33/11.53)	ND.KI......NRIPVNAVK....PRPS........S...................PGVA......................KLPSTS..
  273-  324 (93.06/39.47)	QD.TV.....TKRSLVYAPKGPPVPSPS........SRDSP..LS.SSQPV...SSPAQAS..................YAEKLPHSSHR
  342-  392 (54.52/20.15)	QDaSA.....TLESPTASPSASLPPQNS........ELQRP..TSeGAVAV...SDDTDGS..................AA...PNSEHK
  479-  532 (49.07/17.41)	QV.QV.....Q....IPAPAPGPSPNPFhqtnwkelSRNEI..IQ.SYLNL...QSNVLNS..................SGVQAP.SAH.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.63|      10|      18|     420|     429|       3
---------------------------------------------------------------------------
  420-  429 (18.28/ 8.36)	KERRLTFDPV
  454-  463 (15.34/ 6.01)	ESRRRTESTV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20695 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ISKMASYDISVSPPPTNGIAGSPDALPDQDVVPSPDRSRIENLDNDKINRIPVNAVKPRPSSPGVAKLPSTSSLIKVAVMQQQARLDEGGGGGGYYQAKSPRGVTTSPRSMKQDTVTKRSLVYAPKGPPVPSPSSRDSPLSSSQPVSSPAQASYAEKLPHSSHRSSMHWASSSEVPSHCPPQDASATLESPTASPSASLPPQNSELQRPTSEGAVAVSDDTDGSAAPNSEHKRRKYRSRDYSVNLDGQKIEDMTKPVRLKERRLTFDPVTGQIKHLVHKEPSQTEDFPIPDLSESRRRTESTVQQPAAPAPAPAPALVQVQVQIPAPAPGPSPNPFHQTNWK
2) KIRNDVHNTYSPKAEKSSSRKRRAELRESGVHL
161
125
502
157










Molecular Recognition Features






MoRF SequenceStartStop




NANANA