<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP20687

Description Putative transcription elongation factor A protein 3 isoform 3
SequenceMTREEDLIRMAKKLDKMVSRNNMEGAMDLLTELKGFNMTLKLLQETRIGMSVNGIRKHCTDEEVIALAKVLIKDWKRLLDSGNSHAEKPAEGKNGLDSDKTAVSPNGSPCETQSRKDSSDSKPPPPKKPSLDVKKEKHRKESCDSKPTGQPVKRHSADTKPDRRESTDSKKSSSLPAKKLTGERRESHGSKTSQPGPPQRKPSFDSTERKGKLDAPKTPTTPTSPMSPSFSSAGGPLSPHLATGDSVRDKCIEMLAAALRTDNDFKDFPANCDGMAAEIEDHIYQEIKATDMKYKNRVRSRISNLKDPKNPGLRRNVLAGSIDLSRLASMSAEEMASDELKQLRNVLTQEAIREHQMAKTGGTSTDLLQCGKCKKRNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC
Length408
PositionUnknown
OrganismScophthalmus maximus (Turbot) (Psetta maxima)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Carangaria> Pleuronectiformes> Pleuronectoidei> Scophthalmidae> Scophthalmus.
Aromaticity0.03
Grand average of hydropathy-0.955
Instability index57.96
Isoelectric point9.28
Molecular weight45231.88
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
translation elongation factor activity	GO:0003746	IEA:UniProtKB-KW
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP20687
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     124.35|      22|      23|     115|     136|       1
---------------------------------------------------------------------------
   80-   99 (21.71/ 6.58)	..DSGNSHA..EKPAEGKNGLDS.D
  115-  136 (42.11/18.68)	RKDSSDSKP..PPPKKPSLDVKK.E
  139-  162 (35.81/14.94)	RKESCDSKPtgQPVKRHSADTKP.D
  163-  181 (24.73/ 8.37)	RRESTDSK......KSSSLPAKKlT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.19|      23|      26|     183|     206|       2
---------------------------------------------------------------------------
  183-  206 (39.67/23.75)	ERRES..HGSKT.SQPGPPQrKPSFDS
  207-  232 (33.52/15.51)	TERKGklDAPKTpTTPTSPM.SPSFSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.82|      13|      17|     237|     249|       4
---------------------------------------------------------------------------
  237-  249 (22.51/13.23)	LSPHLATGDSVRD
  255-  267 (21.31/12.19)	LAAALRTDNDFKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.06|      12|      25|     365|     376|       5
---------------------------------------------------------------------------
  365-  376 (22.67/12.39)	TDLLQCGKCKKR
  393-  404 (23.39/12.97)	TTFVLCNECGNR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP20687 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LLDSGNSHAEKPAEGKNGLDSDKTAVSPNGSPCETQSRKDSSDSKPPPPKKPSLDVKKEKHRKESCDSKPTGQPVKRHSADTKPDRRESTDSKKSSSLPAKKLTGERRESHGSKTSQPGPPQRKPSFDSTERKGKLDAPKTPTTPTSPMSPSFSSAGGPLSPHLATGDSVRD
78
249










Molecular Recognition Features






MoRF SequenceStartStop




NANANA